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Select item 112878851.

Targeting TXNIP in endothelial progenitors mitigates IL-8-induced neutrophil recruitment under metabolic stress

Julia Jolibois, Alison Domingues, Divina El Hamaoui, Raphaël Awaida, Mathilde Berger-de-Gaillardo, Daniel Guérin, David M Smadja, Perrine Marquet-DeRougé, Isabelle Margaill, Elisa Rossi, Valérie Nivet-Antoine

Stem Cell Res Ther. 2024; 15: 225. Published online 2024 Jul 29. doi: 10.1186/s13287-024-03850-w

PMCID:: PMC11287885

Abstract Article PDF–5.2M

Select item 112566992.

Increased level of TXNIP and nuclear translocation of TXN is associated with end stage renal disease and development of multiplex renal tumours

Tamas Beothe, Janos Docs, Gyula Kovacs, Lehel Peterfi

BMC Nephrol. 2024; 25: 227. Published online 2024 Jul 17. doi: 10.1186/s12882-024-03653-4

PMCID:: PMC11256699

Abstract Article PDF–1.6M

Select item 111593473.

Involvement of thioredoxin‐binding protein 2 in the antitumor activity of CD437

Saori Matsuoka, Hiroyuki Tsuchiya, Tomohiko Sakabe, Yumi Watanabe, Yoshiko Hoshikawa, Akihiro Kurimasa, Hiroaki Itamochi, Tasuku Harada, Naoki Terakawa, Hiroshi Masutani, Junji Yodoi, Goshi Shiota

Cancer Sci. 2008 Dec; 99(12): 2485–2490. Published online 2008 Nov 19. doi: 10.1111/j.1349-7006.2008.00979.x

PMCID:: PMC11159347

Abstract Article PDF–237K

Select item 110180244.

TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease

Yunxia Du, Ming Wu, Shan Song, Yawei Bian, Yonghong Shi

Ren Fail. 2024; 46(1): 2338933. Published online 2024 Apr 14. doi: 10.1080/0886022X.2024.2338933

PMCID:: PMC11018024

Abstract Article PDF–9.6M

Select item 109470815.

Thioredoxin-Interacting Protein (TXNIP) Associated NLRP3 Inflammasome Activation in Human Alzheimer’s Disease Brain

Lexiao Li, Saifudeen Ismael, Sanaz Nasoohi, Kazuko Sakata, Francesca-Fang Liao, Michael P. McDonald, Tauheed Ishrat

J Alzheimers Dis. Author manuscript; available in PMC 2024 Mar 18.

Published in final edited form as: J Alzheimers Dis. 2019; 68(1): 255–265. doi: 10.3233/JAD-180814

PMCID:: PMC10947081

Abstract Article PDF–1.1M

Select item 109457076.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 108982047.

KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling

Yuan Chen, Lifeng Sun, Haiyan Liu, Jiamei Li, Lu Guo, Zhiyi Wang

Immun Inflamm Dis. 2024 Feb; 12(2): e1199. Published online 2024 Feb 27. doi: 10.1002/iid3.1199

PMCID:: PMC10898204

Abstract Article PDF–1.8M

Select item 108774468.

DNA Methylation of TXNIP Independently Associated with Inflammation and Diabetes Mellitus in Twins

Yijin Xiang, Zeyuan Wang, Qin Hui, Marta Gwinn, Viola Vaccarino, Yan V. Sun

Twin Res Hum Genet. Author manuscript; available in PMC 2024 Feb 20.

Published in final edited form as: Twin Res Hum Genet. 2021 Oct; 24(5): 273–280. Published online 2021 Nov 2. doi: 10.1017/thg.2021.42

PMCID:: PMC10877446

Abstract Article PDF–455K

Select item 107580969.

TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production

Eunhye Jung, Eun Bok Baek, Eun-Ju Hong, Jee Hyun Kang, Suyoung Park, Sehee Park, Eui-Ju Hong, Young-Eun Cho, Je-Won Ko, Young-Suk Won, Hyo-Jung Kwon

Int J Biol Sci. 2024; 20(2): 606–620. Published online 2024 Jan 1. doi: 10.7150/ijbs.90781

PMCID:: PMC10758096

Abstract Article PDF–8.8M

Select item 1070390210.

The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control

Jinhai Deng, Teng Pan, Zaoqu Liu, Caitlin McCarthy, Jose M. Vicencio, Lulu Cao, Giovanna Alfano, Ali Abdulnabi Suwaidan, Mingzhu Yin, Richard Beatson, Tony Ng

Br J Cancer. 2023 Dec 7; 129(12): 1877–1892. Published online 2023 Oct 4. doi: 10.1038/s41416-023-02442-4

PMCID:: PMC10703902

Abstract Article PDF–1.8M

Select item 1055300611.

USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein

Songchang Shi, Xiaobin Pan, Minyong Chen, Lihui Zhang, Shujuan Zhang, Xincai Wang, Songjing Shi, Zhixin Chen, Wei Lin, Yi Jiang

Hepatol Commun. 2023 Aug; 7(8): e0193. Published online 2023 Aug 3. doi: 10.1097/HC9.0000000000000193

PMCID:: PMC10553006

Abstract Article PDF–1.7M

Select item 1019686112.

TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer’s diseases

Junhyung Kim, Jaejoon Lim, Ik Dong Yoo, Samel Park, Jong-Seok Moon

Redox Biol. 2023 Jul; 63: 102735. Published online 2023 May 6. doi: 10.1016/j.redox.2023.102735

PMCID:: PMC10196861

Abstract Article PDF–13M

Select item 1017968413.

The Role of Txnip in Mediating Low-Magnesium-Driven Endothelial Dysfunction

Laura Locatelli, Giorgia Fedele, Jeanette A. Maier

Int J Mol Sci. 2023 May; 24(9): 8351. Published online 2023 May 6. doi: 10.3390/ijms24098351

PMCID:: PMC10179684

Abstract Article PDF–3.6M

Select item 1008464514.

High TXNIP expression accelerates the migration and invasion of the GDM placenta trophoblast

Rina Sa, Jing Ma, Jie Yang, Dong Fang Li, Jie Du, Jian Chao Jia, Zhi Ying Li, Na Huang, Lamusi A, Rula Sha, Gal Nai, Bayar Hexig, Ji Qing Meng, Lan Yu

BMC Pregnancy Childbirth. 2023; 23: 235. Published online 2023 Apr 10. doi: 10.1186/s12884-023-05524-6

PMCID:: PMC10084645

Abstract Article PDF–2.4M

Select item 998652015.

Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin

Susan J. Qualls-Histed, Casey P. Nielsen, Jason A. MacGurn

iScience. 2023 Mar 17; 26(3): 106150. Published online 2023 Feb 6. doi: 10.1016/j.isci.2023.106150

PMCID:: PMC9986520

Abstract Article PDF–9.6M

Select item 996862816.

Physiological and Pathophysiological Roles of Thioredoxin Interacting Protein: A Perspective on Redox Inflammation and Metabolism

Sezin Dagdeviren, Richard T. Lee, Ning Wu

Antioxid Redox Signal. February 2023; 38(4): 442–460. Published online 2023 Feb 14. doi: 10.1089/ars.2022.0022

PMCID:: PMC9968628

Abstract Article PDF–718K

Select item 995328717.

Various Expressions of PIK3C2A and TXNIP Genes and Their Potential Role as Independent Risk Factors for Chronic Stable Angina and Acute Coronary Syndrome

Shimaa E. Soliman, Mai A. H. Abouelenin, Neven I. Samy, Marwa M. Omar, Abeer A. Alrefai

Biomolecules. 2023 Feb; 13(2): 302. Published online 2023 Feb 6. doi: 10.3390/biom13020302

PMCID:: PMC9953287

Abstract Article PDF–1.4M

Select item 992625018.

Thioredoxin-interacting protein is essential for memory T cell formation via the regulation of the redox metabolism

Kota Kokubo, Kiyoshi Hirahara, Masahiro Kiuchi, Kaori Tsuji, Yuki Shimada, Yuri Sonobe, Rie Shinmi, Takahisa Hishiya, Chiaki Iwamura, Atsushi Onodera, Toshinori Nakayama

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2218345120. Published online 2023 Jan 3. doi: 10.1073/pnas.2218345120

PMCID:: PMC9926250

Abstract Article PDF–3.3M

Select item 989053219.

Novel lncRNA‐prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease

Yi Song, Feng Guo, Yan‐yan Zhao, Xiao‐jun Ma, Li‐na Wu, Ji‐feng Yu, Hong‐fei Ji, Ming‐wei Shao, Feng‐juan Huang, Lin Zhao, Xun‐jie Fan, Ya‐nan Xu, Qing‐zhu Wang, Gui‐jun Qin

Cell Prolif. 2023 Feb; 56(2): e13349. Published online 2022 Oct 31. doi: 10.1111/cpr.13349

PMCID:: PMC9890532

Abstract Article PDF–28M

Select item 982904320.

TXNIP Suppresses the Osteochondrogenic Switch of Vascular Smooth Muscle Cells in Atherosclerosis

Sang-Ho Woo, Dongsoo Kyung, Seung Hyun Lee, Kyu Seong Park, Minkyu Kim, Kibyeong Kim, Hyo-Jung Kwon, Young-Suk Won, Inpyo Choi, Young-Jun Park, Du-Min Go, Jeong-Seop Oh, Won Kee Yoon, Seung Sam Paik, Ji Hyeon Kim, Yong-Hwan Kim, Jae-Hoon Choi, Dae-Yong Kim

Circ Res. 2023 Jan 6; 132(1): 52–71. Published online 2022 Dec 1. doi: 10.1161/CIRCRESAHA.122.321538