PMC Links for GEO Profiles (Select 32549797) - PMC

Select item 109923031.

COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade

Kyle Hansen, Sandeep Kumar, Kathryn Logronio, Sarah Whelan, Samir Qurashi, Hsin-Yuan Cheng, Andrew Drake, Margaret Tang, Patrick Wall, David Bernados, Ling Leung, Eran Ophir, Zoya Alteber, Gady Cojocaru, Moran Galperin, Masha Frenkel, Mark White, John Hunter, Spencer C. Liang, Maya F. Kotturi

Cancer Immunol Immunother. 2021 Dec; 70(12): 3525–3540. Published online 2021 Apr 26. doi: 10.1007/s00262-021-02921-8

PMCID:: PMC10992303

Abstract Article PDF–2.4M

Select item 88421652.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 86341993.

PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia

Jessica Li, Sarah Whelan, Maya F. Kotturi, Deborah Meyran, Criselle D’Souza, Kyle Hansen, Spencer Liang, John Hunter, Joseph A. Trapani, Paul J. Neeson

Haematologica. 2021 Dec 1; 106(12): 3115–3124. Published online 2020 Nov 5. doi: 10.3324/haematol.2020.258574

PMCID:: PMC8634199

Abstract Article PDF–1.4M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78514445.

Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy

Hyung-seung Jin, Yoon Park

BMB Rep. 2021 Jan 31; 54(1): 2–11. Published online 2021 Jan 31. doi: 10.5483/BMBRep.2021.54.1.229

PMCID:: PMC7851444

Abstract Article PDF–1.2M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70017347.

PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8⁺ T-cell Function

Sarah Whelan, Eran Ophir, Maya F. Kotturi, Ofer Levy, Sudipto Ganguly, Ling Leung, Ilan Vaknin, Sandeep Kumar, Liat Dassa, Kyle Hansen, David Bernados, Benjamin Murter, Abha Soni, Janis M. Taube, Amanda Nickles Fader, Tian-Li Wang, Ie-Ming Shih, Mark White, Drew M. Pardoll, Spencer C. Liang

Cancer Immunol Res. Author manuscript; available in PMC 2020 Feb 5.

Published in final edited form as: Cancer Immunol Res. 2019 Feb; 7(2): 257–268. Published online 2019 Jan 18. doi: 10.1158/2326-6066.CIR-18-0442

PMCID:: PMC7001734

Abstract Article PDF–3.0M

Select item 64975698.

Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy

Changlong Liu, Carolyn E. Banister, Phillip J. Buckhaults

Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Res. 2019 May 1; 79(9): 2392–2403. Published online 2019 Mar 12. doi: 10.1158/0008-5472.CAN-18-3024

PMCID:: PMC6497569

Abstract Article PDF–2.2M

Select item 57092209.

Blockade of CD112R and TIGIT signaling sensitizes human natural killer cell functions

Feng Xu, Alexander Sunderland, Yue Zhou, Richard D. Schulick, Barish H. Edil, Yuwen Zhu

Cancer Immunol Immunother. 2017 Oct; 66(10): 1367–1375. Published online 2017 Jun 16. doi: 10.1007/s00262-017-2031-x

PMCID:: PMC5709220

Abstract Article PDF–2.5M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 474909111.

Identification of CD112R as a novel checkpoint for human T cells

Yuwen Zhu, Alessandro Paniccia, Alexander C. Schulick, Wei Chen, Michelle R. Koenig, Joshua T. Byers, Sheng Yao, Shaun Bevers, Barish H. Edil

J Exp Med. 2016 Feb 8; 213(2): 167–176. doi: 10.1084/jem.20150785

PMCID:: PMC4749091

Abstract Article PDF–2.0M

Select item 464794112.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461721113.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 13924115.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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