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Select item 111593901.

Novel centrosome protein, TCC52, is a cancer‐testis antigen

Sichen Li, Xiaohua Hu, Shuang Cui, Dacheng He

Cancer Sci. 2008 Nov; 99(11): 2274–2279. Published online 2008 Oct 14. doi: 10.1111/j.1349-7006.2008.00937.x

PMCID:: PMC11159390

Abstract Article PDF–288K

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 99296313.

Recognition of the CCT5 di‐Glu degron by CRL4^DCAF12 is dependent on TRiC assembly

Carlos Pla‐Prats, Simone Cavadini, Georg Kempf, Nicolas H Thomä

EMBO J. 2023 Feb; 42(4): e112253. Published online 2023 Jan 30. doi: 10.15252/embj.2022112253

PMCID:: PMC9929631

Abstract Article PDF–4.3M

Select item 92316234.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90163206.

A Hypoxia-Induced SCF^FBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis

Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou

Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373

PMCID:: PMC9016320

Abstract Article PDF–3.0M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81610148.

CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation

Tomas Lidak, Nikol Baloghova, Vladimir Korinek, Radislav Sedlacek, Jana Balounova, Petr Kasparek, Lukas Cermak

Int J Mol Sci. 2021 May; 22(10): 5394. Published online 2021 May 20. doi: 10.3390/ijms22105394

PMCID:: PMC8161014

Abstract Article PDF–7.9M

Select item 73220679.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 693867410.

CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleus

Yong Suk Cho, Shuang Li, Xiaohui Wang, Jian Zhu, Shu Zhuo, Yuhong Han, Tao Yue, Yingzi Yang, Jin Jiang

Genes Dev. 2020 Jan 1; 34(1-2): 53–71. doi: 10.1101/gad.333146.119

PMCID:: PMC6938674

Abstract Article PDF–30M

Select item 660700711.

Regulation of MAGE‐A3/6 by the CRL4‐DCAF12 ubiquitin ligase and nutrient availability

Ramya Ravichandran, Kiran Kodali, Junmin Peng, Patrick Ryan Potts

EMBO Rep. 2019 Jul; 20(7): e47352. Published online 2019 May 24. doi: 10.15252/embr.201847352

PMCID:: PMC6607007

Abstract Article PDF–2.7M

Select item 600388112.

The Eukaryotic Proteome is Shaped by E3 Ubiquitin Ligases Targeting C-terminal Degrons

Itay Koren, Richard T. Timms, Tomasz Kula, Qikai Xu, Mamie Z. Li, Stephen J. Elledge

Cell. Author manuscript; available in PMC 2019 Jun 14.

Published in final edited form as: Cell. 2018 Jun 14; 173(7): 1622–1635.e14. Published online 2018 May 17. doi: 10.1016/j.cell.2018.04.028

PMCID:: PMC6003881

Abstract Article PDF–933K

Select item 561217313.

The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex

Meraj H. Khan, Siiri I. Salomaa, Guillaume Jacquemet, Umar Butt, Mitro Miihkinen, Takahiro Deguchi, Elena Kremneva, Pekka Lappalainen, Martin J. Humphries, Jeroen Pouwels

J Cell Sci. 2017 Sep 15; 130(18): 3094–3107. doi: 10.1242/jcs.200329

Correction in:: J Cell Sci. 2023 Oct 1; 136(19): jcs261581.

PMCID:: PMC5612173

Abstract Article

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 300858616.

Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics

Eric J. Bennett, John Rush, Steven P. Gygi, J. Wade Harper

Cell. Author manuscript; available in PMC 2011 Dec 10.

Published in final edited form as: Cell. 2010 Dec 10; 143(6): 951–965. doi: 10.1016/j.cell.2010.11.017

PMCID:: PMC3008586

Abstract Article PDF–3.0M

Select item 298946117.

Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins

James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters

Science. Author manuscript; available in PMC 2010 Nov 22.

Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348

PMCID:: PMC2989461

Abstract Article PDF–2.2M

Select item 282328818.

A Promiscuous α-Helical Motif Anchors Viral Hijackers and Substrate Receptors to the CUL4-DDB1 Ubiquitin Ligase Machinery

Ti Li, Eva I. Robert, Pieter C. van Breugel, Michel Strubin, Ning Zheng

Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Nat Struct Mol Biol. 2010 Jan; 17(1): 105. Published online 2009 Dec 6. doi: 10.1038/nsmb.1719

PMCID:: PMC2823288

Abstract Article PDF–1.3M

Select item 272093319.

An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases

Michael Hans Olma, Marcia Roy, Thierry Le Bihan, Izabela Sumara, Sarah Maerki, Brett Larsen, Manfredo Quadroni, Matthias Peter, Mike Tyers, Lionel Pintard

J Cell Sci. 2009 Apr 1; 122(7): 1035–1044. Published online 2009 Mar 18. doi: 10.1242/jcs.043539

PMCID:: PMC2720933

Abstract Article

Select item 268304720.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

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