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Items: 1 to 20 of 74

1.
DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells
Sanni Alve, Silvia Gramolelli, Joonas Jukonen, Susanna Juteau, Anne Pink, Atte A. Manninen, Satu Hänninen, Elisa Monto, Madeleine H. Lackman, Olli Carpén, Pipsa Saharinen, Sinem Karaman, Kari Vaahtomeri, Päivi M. Ojala
JCI Insight. 2024 Jan 9; 9(1): e171821. Published online 2024 Jan 9. doi: 10.1172/jci.insight.171821
PMCID:
PMC10906450
AbstractArticlePDF–9.8M
2.
Palmitic acid in type 2 diabetes mellitus promotes atherosclerotic plaque vulnerability via macrophage Dll4 signaling
Xiqiang Wang, Ling Zhu, Jing Liu, Yanpeng Ma, Chuan Qiu, Chengfeng Liu, Yangchao Gong, Ya Yuwen, Gongchang Guan, Yong Zhang, Shuo Pan, Junkui Wang, Zhongwei Liu
Nat Commun. 2024; 15: 1281. Published online 2024 Feb 12. doi: 10.1038/s41467-024-45582-8
PMCID:
PMC10861578
AbstractArticlePDF–4.5M
3.
Expressions and Prognostic Values of Notch3 and DLL4 in Human Breast Cancer
Lin Wang, Ge Cao, Wei Li, Xiao-Wen Chen, Shi-Shuang Xiong, Ya-Nan Mu, Jin-Fang Jiang, Lan Yang, De-Rui Zhang, Yu-Wen Cao
Technol Cancer Res Treat. 2023; 22: 15330338221118984. Published online 2023 Feb 6. doi: 10.1177/15330338221118984
PMCID:
PMC9903027
AbstractArticlePDF–1.6M
4.
NOTCH1 AND DLL4 ARE INVOLVED IN THE HUMAN TUBERCULOSIS PROGRESSION AND IMMUNE RESPONSE ACTIVATION
Ricardo C. Castro, Fabiana A. Zambuzi, Caroline Fontanari, Fabiana R. de Morais, Valdes R. Bollela, Steven L. Kunkel, Matthew A. Schaller, Fabiani G. Frantz
Tuberculosis (Edinb) Author manuscript; available in PMC 2022 Nov 7.
Published in final edited form as: Tuberculosis (Edinb). 2020 Sep; 124: 101980. Published online 2020 Aug 8. doi: 10.1016/j.tube.2020.101980
PMCID:
PMC9639860
AbstractArticlePDF–1.3M
5.
Probing Notch1-Dll4 signaling in regulating osteogenic differentiation of human mesenchymal stem cells using single cell nanobiosensor
Yuwen Zhao, Rui Yang, Zoe Bousraou, Kiarra Richardson, Shue Wang
Sci Rep. 2022; 12: 10315. Published online 2022 Jun 20. doi: 10.1038/s41598-022-14437-x
PMCID:
PMC9209437
AbstractArticlePDF–4.8M
6.
DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system
Ashton C. Trotman-Grant, Mahmood Mohtashami, Joshua De Sousa Casal, Elisa C. Martinez, Dylan Lee, Sintia Teichman, Patrick M. Brauer, Jianxun Han, Michele K. Anderson, Juan Carlos Zúñiga-Pflücker
Nat Commun. 2021; 12: 5023. Published online 2021 Aug 18. doi: 10.1038/s41467-021-25245-8
PMCID:
PMC8373879
AbstractArticlePDF–1.8M
7.
Correlation of serum delta-like ligand-4 level with the severity of diabetic retinopathy
Yan Zhu, Jingcheng Hu, Xuan Du, Qionglei Fang, Yingyi Zhou, Ke Chen
BMC Endocr Disord. 2021; 21: 157. Published online 2021 Aug 6. doi: 10.1186/s12902-021-00814-6
PMCID:
PMC8344193
AbstractArticlePDF–642K
8.
O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells
Shuiliang Yu, Weihuan Wang, Marwah Albakri, Xiaoxing Yu, Gurnoor Majihail, Seunghwan Lim, Rachel K Lopilato, Atsuko Ito, John Letterio, Robert S Haltiwanger, Lan Zhou
Glycobiology. 2021 May; 31(5): 582–592. Published online 2020 Dec 22. doi: 10.1093/glycob/cwaa113
PMCID:
PMC8176772
AbstractArticlePDF–1.0M
9.
Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung
Sheng Xia, Heather L. Menden, Nick Townley, Sherry M. Mabry, Jeffrey Johnston, Michael F. Nyp, Daniel P. Heruth, Thomas Korfhagen, Venkatesh Sampath
JCI Insight. 2021 Apr 8; 6(7): e134170. Published online 2021 Apr 8. doi: 10.1172/jci.insight.134170
PMCID:
PMC8119184
AbstractArticlePDF–13M
10.
Dll4/Notch1 signalling pathway is required in collective invasion of salivary adenoid cystic carcinoma
Ke Wang, Hua-Yang Fan, Xing Pang, Mei Zhang, Xiang-Hua Yu, Jia-Shun Wu, Bing-Jun Chen, Jian Jiang, Xin-Hua Liang, Ya-Ling Tang
Oncol Rep. 2021 Mar; 45(3): 1011–1022. Published online 2021 Jan 18. doi: 10.3892/or.2021.7939
Correction in:
Oncol Rep. 2022 Mar; 47(3): 57.
PMCID:
PMC7859997
AbstractArticlePDF–1001K
11.
Synergistic antitumor activity of a DLL4/VEGF bispecific therapeutic antibody in combination with irinotecan in gastric cancer
Da-Hyun Kim, Seul Lee, Hyeok Gu Kang, Hyun-Woo Park, Han-Woong Lee, Dongin Kim, Dong-Hoon Yoem, Jin-Hyung Ahn, Eunsin Ha, Weon-Kyoo You, Sang Hoon Lee, Seok-Jun Kim, Kyung-Hee Chun
BMB Rep. 2020 Oct 31; 53(10): 533–538. Published online 2020 Oct 31. doi: 10.5483/BMBRep.2020.53.10.103
PMCID:
PMC7607148
AbstractArticlePDF–2.3M
12.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
13.
RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain
Esther Bridges, Helen Sheldon, Esther Kleibeuker, Evelyn Ramberger, Christos Zois, Alun Barnard, Ulrike Harjes, Ji-Liang Li, Massimo Masiero, Robert MacLaren, Adrian Harris
Angiogenesis. 2020; 23(3): 493–513. Published online 2020 Jun 6. doi: 10.1007/s10456-020-09726-w
PMCID:
PMC7311507
AbstractArticlePDF–3.5M
14.
Long non-coding RNA UCA1 promotes malignant phenotypes of renal cancer cells by modulating the miR-182-5p/DLL4 axis as a ceRNA
Wei Wang, Wentao Hu, Ya Wang, Yong An, Lei Song, Panfeng Shang, Zhongjin Yue
Mol Cancer. 2020; 19: 18. Published online 2020 Jan 29. doi: 10.1186/s12943-020-1132-x
Correction in:
Mol Cancer. 2022; 21: 3.
PMCID:
PMC6988374
AbstractArticlePDF–4.3M
15.
Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy
Elisabeth Silkenstedt, Fabian Arenas, Berta Colom-Sanmartí, Sílvia Xargay-Torrent, Morihiro Higashi, Ariadna Giró, Vanina Rodriguez, Patricia Fuentes, Walter E. Aulitzky, Heiko van der Kuip, Sílvia Beà, Maria L. Toribio, Elias Campo, Mònica López-Guerra, Dolors Colomer
J Exp Clin Cancer Res. 2019; 38: 446. Published online 2019 Nov 1. doi: 10.1186/s13046-019-1458-7
PMCID:
PMC6825347
AbstractArticlePDF–2.4M
16.
DLL4 and Jagged1 are Angiogenic Targets of Orphan Nuclear Receptor TR3/Nur77
Jin Peng, Shengqiang Zhao, Yan Li, Gengming Niu, Chen Chen, Taiyang Ye, Dezheng Zhao, Huiyan Zeng
Microvasc Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Microvasc Res. 2019 Jul; 124: 67–75. Published online 2019 Mar 28. doi: 10.1016/j.mvr.2019.03.006
PMCID:
PMC6474785
AbstractArticlePDF–1.2M
17.
Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes
Xiaowei Zheng, Sampath Narayanan, Vivekananda Gupta Sunkari, Sofie Eliasson, Ileana Ruxandra Botusan, Jacob Grünler, Anca Irinel Catrina, Freddy Radtke, Cheng Xu, Allan Zhao, Neda Rajamand Ekberg, Urban Lendahl, Sergiu-Bogdan Catrina
Proc Natl Acad Sci U S A. 2019 Apr 2; 116(14): 6985–6994. Published online 2019 Mar 18. doi: 10.1073/pnas.1900351116
PMCID:
PMC6452711
AbstractArticlePDF–2.3M
18.
A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool
Marta G. Del Barrio, Raquel Taveira-Marques, Yuko Muroyama, Dong-In Yuk, Shengguo Li, Mary Wines-Samuelson, Jie Shen, Hazel K. Smith, Mengqing Xiang, David Rowitch, William D. Richardson
Development. Author manuscript; available in PMC 2019 Jan 11.
Published in final edited form as: Development. 2007 Oct; 134(19): 3427–3436. Published online 2007 Aug 29. doi: 10.1242/dev.005868
PMCID:
PMC6329449
AbstractArticlePDF–4.1M
19.
Delta-like ligand 4 in hepatocellular carcinoma intrinsically promotes tumour growth and suppresses hepatitis B virus replication
Areerat Kunanopparat, Jiraphorn Issara-Amphorn, Asada Leelahavanichkul, Anapat Sanpavat, Suthiluk Patumraj, Pisit Tangkijvanich, Tanapat Palaga, Nattiya Hirankarn
World J Gastroenterol. 2018 Sep 14; 24(34): 3861–3870. Published online 2018 Sep 14. doi: 10.3748/wjg.v24.i34.3861
PMCID:
PMC6141339
AbstractArticlePDF–1.9M
20.
Spatial patterning of the Notch ligand Dll4 controls endothelial sprouting in vitro
L. A. Tiemeijer, J-P. Frimat, O. M. J. A. Stassen, C. V. C. Bouten, C. M. Sahlgren
Sci Rep. 2018; 8: 6392. Published online 2018 Apr 23. doi: 10.1038/s41598-018-24646-y
PMCID:
PMC5913301
AbstractArticlePDF–3.2M

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