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Select item 112294171.

Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation

Yahui Lan, Kelly M. Banks, Heng Pan, Nipun Verma, Gary R. Dixon, Ting Zhou, Bo Ding, Olivier Elemento, Shuibing Chen, Danwei Huangfu, Todd Evans

Cell Rep. Author manuscript; available in PMC 2024 Jul 8.

Published in final edited form as: Cell Rep. 2021 Dec 7; 37(10): 110095. doi: 10.1016/j.celrep.2021.110095

PMCID:: PMC11229417

Abstract Article PDF–3.1M

Select item 109332672.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 109136963.

TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy

Ji Ren, Xiuying Chen, Jing Li, Yuxin Zan, Shan Wang, Yujie Tan, Yan Ding

Epigenetics. 2024; 19(1): 2323751. Published online 2024 Mar 3. doi: 10.1080/15592294.2024.2323751

PMCID:: PMC10913696

Abstract Article PDF–5.9M

Select item 107663444.

Crosstalk between RNA m⁶A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells

Tongyu Sun, Yueyuan Xu, Yu Xiang, Jianhong Ou, Erik J Soderblom, Yarui Diao

Nat Genet. Author manuscript; available in PMC 2024 Jan 4.

Published in final edited form as: Nat Genet. 2023 Aug; 55(8): 1324–1335. Published online 2023 Jul 20. doi: 10.1038/s41588-023-01452-5

PMCID:: PMC10766344

Abstract Article PDF–3.8M

Select item 105302065.

Role of TET1-mediated epigenetic modulation in Alzheimer’s disease

Matthew J. Armstrong, Yulin Jin, Selina M. Vattathil, Yanting Huang, Jason P. Schroeder, David A. Bennet, Zhaohui S. Qin, Thomas S. Wingo, Peng Jin

Neurobiol Dis. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Neurobiol Dis. 2023 Sep; 185: 106257. Published online 2023 Aug 8. doi: 10.1016/j.nbd.2023.106257

PMCID:: PMC10530206

Abstract Article PDF–1.9M

Select item 103995306.

Functional polymorphisms of the TET1 gene increase the risk of neuroblastoma in Chinese children

Jiaming Chang, Lei Lin, Chunlei Zhou, Xinxin Zhang, Tianyou Yang, Haiyan Wu, Yan Zou, Jing He

J Cell Mol Med. 2023 Aug; 27(15): 2239–2248. Published online 2023 Jun 22. doi: 10.1111/jcmm.17820

PMCID:: PMC10399530

Abstract Article PDF–1.6M

Select item 103346457.

MiR-183-5p promotes migration and invasion of prostate cancer by targeting TET1

Yuehua Feng, Kai Wang, Minchao Qin, Qianfeng Zhuang, Zhen Chen

BMC Urol. 2023; 23: 116. Published online 2023 Jul 10. doi: 10.1186/s12894-023-01286-7

PMCID:: PMC10334645

Abstract Article PDF–1.8M

Select item 101819358.

Hypoxia switches TET1 from being tumor-suppressive to oncogenic

Qi Yang, Hui Dang, Jiaxin Liu, Xingye Wang, Jingyuan Wang, Xinhui Lan, Meiju Ji, Mingzhao Xing, Peng Hou

Oncogene. 2023; 42(20): 1634–1648. Published online 2023 Apr 5. doi: 10.1038/s41388-023-02659-w

PMCID:: PMC10181935

Abstract Article PDF–5.3M

Select item 97696989.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 966515410.

MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia

Anastasia E. Hains, Sakshi Uppal, John Z. Cao, Helen R. Salwen, Mark A. Applebaum, Susan L. Cohn, Lucy A. Godley

Epigenetics. 2022; 17(13): 2056–2074. Published online 2022 Aug 8. doi: 10.1080/15592294.2022.2106078

PMCID:: PMC9665154

Abstract Article PDF–3.3M

Select item 953239511.

Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer

Xiaolong Tang, Yahang Liang, Guorui Sun, Qingsi He, Zhenyu Hou, Xingzhi Jiang, Peng Gao, Hui Qu

Cell Death Dis. 2022 Oct; 13(10): 848. Published online 2022 Oct 4. doi: 10.1038/s41419-022-05299-2

PMCID:: PMC9532395

Abstract Article PDF–8.2M

Select item 944012212.

Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation

María Arroyo, Florian D. Hastert, Andreas Zhadan, Florian Schelter, Susanne Zimbelmann, Cathia Rausch, Anne K. Ludwig, Thomas Carell, M. Cristina Cardoso

Nat Commun. 2022; 13: 5173. Published online 2022 Sep 2. doi: 10.1038/s41467-022-32799-8

Correction in:: Nat Commun. 2023; 14: 369.

PMCID:: PMC9440122

Abstract Article PDF–9.3M

Select item 935722513.

YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis

Bo-Kuan Wu, Szu-Chieh Mei, Elizabeth H. Chen, Yonggang Zheng, Duojia Pan

Nat Genet. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Nat Genet. 2022 Aug; 54(8): 1202–1213. Published online 2022 Jul 14. doi: 10.1038/s41588-022-01119-7

PMCID:: PMC9357225

Abstract Article PDF–9.1M

Select item 926314414.

TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiation

Jianfang Li, Xinwei Wu, Jie Ke, Minjung Lee, Qingping Lan, Jia Li, Jianxiu Yu, Yun Huang, De-Qiang Sun, Ruiyu Xie

Nat Commun. 2022; 13: 3907. Published online 2022 Jul 7. doi: 10.1038/s41467-022-31611-x

PMCID:: PMC9263144

Abstract Article PDF–4.8M

Select item 914048415.

Single-Cell RNA-Seq Analysis Reveals Lung Epithelial Cell Type-Specific Responses to HDM and Regulation by Tet1

Tao Zhu, Anthony P. Brown, Lucy P. Cai, Gerald Quon, Hong Ji

Genes (Basel) 2022 May; 13(5): 880. Published online 2022 May 14. doi: 10.3390/genes13050880

PMCID:: PMC9140484

Abstract Article PDF–2.7M

Select item 911973616.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 899185117.

TET1 mutations as a predictive biomarker for immune checkpoint inhibitors in colon adenocarcinoma

Tianzhu Qiu, Xiaoxuan Wang, Furong Du, Xiangjing Hu, Fujun Sun, Chao Song, Jie Zhao

World J Surg Oncol. 2022; 20: 115. Published online 2022 Apr 8. doi: 10.1186/s12957-022-02581-7

PMCID:: PMC8991851

Abstract Article PDF–2.1M

Select item 897404318.

A novel epigenetic marker, Ten-eleven translocation family member 2 (TET2), is identified in the intractable epileptic brain and regulates ATP binding cassette subfamily B member 1 (ABCB1) in the blood–brain barrier

Fan-Cheng Kong, Li-Qin Lang, Jie Hu, Xia-Ling Zhang, Ming-Kang Zhong, Chun-Lai Ma

Bioengineered. 2022; 13(3): 6638–6649. Published online 2022 Mar 2. doi: 10.1080/21655979.2022.2045838

PMCID:: PMC8974043

Abstract Article PDF–1.3M

Select item 894490619.

FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation

Haibo Yang, Yumin Wang, Yufei Xiang, Tribhuwan Yadav, Jian Ouyang, Laiyee Phoon, Xueping Zhu, Yi Shi, Lee Zou, Li Lan

Proc Natl Acad Sci U S A. 2022 Mar 22; 119(12): e2116251119. Published online 2022 Mar 15. doi: 10.1073/pnas.2116251119

PMCID:: PMC8944906

Abstract Article PDF–2.6M

Select item 876331720.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

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