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Items: 1 to 20 of 65

1.
NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation
Mina Noura, Sakura Tomita, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa
Cancer Med. 2024 Jul; 13(13): e7445. Published online 2024 Jun 28. doi: 10.1002/cam4.7445
PMCID:
PMC11212001
ArticlePDF–6.4M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
3.
Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP
Zeynep Cakir, Samuel J. Lord, Yuan Zhou, Gwendolyn M. Jang, Benjamin J. Polacco, Manon Eckhardt, David Jimenez-Morales, Billy W. Newton, Adam L. Orr, Jeffrey R. Johnson, Alexandre da Cruz, R. Dyche Mullins, Nevan J. Krogan, Robert W. Mahley, Danielle L. Swaney
Mol Cell Proteomics. 2023 May; 22(5): 100541. Published online 2023 Apr 4. doi: 10.1016/j.mcpro.2023.100541
PMCID:
PMC10196575
ArticlePDF–4.5M
4.
D-Aspartate Depletion Perturbs Steroidogenesis and Spermatogenesis in Mice
Alessandra Santillo, Sara Falvo, Massimo Venditti, Anna Di Maio, Gabriella Chieffi Baccari, Francesco Errico, Alessandro Usiello, Sergio Minucci, Maria Maddalena Di Fiore
Biomolecules. 2023 Apr; 13(4): 621. Published online 2023 Mar 30. doi: 10.3390/biom13040621
PMCID:
PMC10136051
ArticlePDF–4.1M
5.
The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML
Emily B. Heikamp, Jill A. Henrich, Florian Perner, Eric M. Wong, Charles Hatton, Yanhe Wen, Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah J. Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M. McGeehan, Edward A. Kolb, Alex Kentsis, Scott A. Armstrong
Blood. 2022 Feb 10; 139(6): 894–906. doi: 10.1182/blood.2021012806
PMCID:
PMC8832476
Article
6.
P2RY12-Inhibitors Reduce Cancer-Associated Thrombosis and Tumor Growth in Pancreatic Cancers
Ana Luisa Palacios-Acedo, Soraya Mezouar, Diane Mège, Lydie Crescence, Christophe Dubois, Laurence Panicot-Dubois
Front Oncol. 2021; 11: 704945. Published online 2021 Sep 13. doi: 10.3389/fonc.2021.704945
PMCID:
PMC8475274
ArticlePDF–14M
7.
Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet
Daixi Jiang, Jianbin Zhang, Shuangzhe Lin, Yuqin Wang, Yuanwen Chen, Jiangao Fan
Front Cell Dev Biol. 2021; 9: 628143. Published online 2021 May 20. doi: 10.3389/fcell.2021.628143
PMCID:
PMC8172602
ArticlePDF–12M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
9.
TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS
Darlene A. Monlish, Zev J. Greenberg, Sima T. Bhatt, Kathryn M. Leonard, Molly P. Romine, Qian Dong, Lauren Bendesky, Eric J. Duncavage, Jeffrey A. Magee, Laura G. Schuettpelz
Exp Hematol. Author manuscript; available in PMC 2020 Nov 18.
Published in final edited form as: Exp Hematol. 2020 Aug; 88: 42–55. Published online 2020 Jul 8. doi: 10.1016/j.exphem.2020.07.001
PMCID:
PMC7673652
ArticlePDF–2.1M
10.
Brief Report: Loss of p15Ink4b Accelerates Development of Myeloid Neoplasms in Nup98-HoxD13 Transgenic Mice
Rita Humeniuk, Richard Koller, Juraj Bies, Peter Aplan, Linda Wolff
Stem Cells. Author manuscript; available in PMC 2020 Nov 4.
Published in final edited form as: Stem Cells. 2014 May; 32(5): 1361–1366. doi: 10.1002/stem.1635
PMCID:
PMC7640373
ArticlePDF–1.0M
11.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
ArticlePDF–2.0M
12.
Prolyl endopeptidase gene disruption attenuates high fat diet-induced nonalcoholic fatty liver disease in mice by improving hepatic steatosis and inflammation
Dai-Xi Jiang, Jian-Bin Zhang, Meng-Ting Li, Shuang-Zhe Lin, Yu-Qin Wang, Yuan-Wen Chen, Jian-Gao Fan
Ann Transl Med. 2020 Mar; 8(5): 218. doi: 10.21037/atm.2020.01.14
PMCID:
PMC7154388
ArticlePDF–14M
13.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
ArticlePDF–1.6M
14.
RAE1 promotes BMAL1 shuttling and regulates degradation and activity of CLOCK: BMAL1 heterodimer
Xulei Zheng, Xu Zhao, Yingying Zhang, Hao Tan, Bojun Qiu, Tengjiao Ma, Jiarong Zeng, Dachang Tao, Yunqiang Liu, Yilu Lu, Yongxin Ma
Cell Death Dis. 2019 Feb; 10(2): 62. Published online 2019 Jan 25. doi: 10.1038/s41419-019-1346-2
PMCID:
PMC6347605
ArticlePDF–3.9M
15.
Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo
Reinis Svarcbahs, Ulrika H. Julku, Susanna Norrbacka, Timo T. Myöhänen
Sci Rep. 2018; 8: 1552. Published online 2018 Jan 24. doi: 10.1038/s41598-018-19823-y
PMCID:
PMC5784134
ArticlePDF–7.2M
16.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
ArticlePDF–31M
17.
NUP98-Fusion Proteins Interact With the NSL and MLL1 Complexes To Drive Leukemogenesis
Haiming Xu, Daria G Valerio, Meghan E Eisold, Amit Sinha, Richard P Koche, Wenhuo Hu, Chun-Wei Chen, S Haihua Chu, Gerard L Brien, Christopher Y. Park, James J. Hsieh, Patricia Ernst, Scott A Armstrong
Cancer Cell. Author manuscript; available in PMC 2017 Dec 12.
Published in final edited form as: Cancer Cell. 2016 Dec 12; 30(6): 863–878. Published online 2016 Nov 23. doi: 10.1016/j.ccell.2016.10.019
PMCID:
PMC5501282
ArticlePDF–1.9M
18.
Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes
Tomasz Szul, Preston E. Bratcher, Kyle B. Fraser, Michele Kong, Rabindra Tirouvanziam, Sarah Ingersoll, Elizabeth Sztul, Sunil Rangarajan, J. Edwin Blalock, Xin Xu, Amit Gaggar
Am J Respir Cell Mol Biol. 2016 Mar; 54(3): 359–369. doi: 10.1165/rcmb.2015-0108OC
PMCID:
PMC5455678
ArticlePDF–1.7M
19.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
ArticlePDF–1.4M
20.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
ArticlePDF–3.0M

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