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Items: 1 to 20 of 29

1.
Apical Shear Stress Enhanced Organic Cation Transport in Human OCT2/MATE1-Transfected Madin-Darby Canine Kidney Cells Involves Ciliary Sensing
Aishwarya Jayagopal, Paul R. Brakeman, Peter Soler, Nicholas Ferrell, William Fissell, Deanna L. Kroetz, Shuvo Roy
J Pharmacol Exp Ther. 2019 Jun; 369(3): 523–530. Published online 2019 Jun. doi: 10.1124/jpet.118.255026
PMCID:
PMC11047058
AbstractArticlePDF–1.1M
2.
The association study between changes in HbA1C with rs2250486 and rs67238751 genetic variants for SLC47A1 in newly diagnosed Iranian patients with type 2 diabetes mellitus: 6 months follow‐up study
Armina Semnani, Faranak Kazerouni, Saeid Kalbasi, Seyedeh Zahra Shahrokhi, Ali Rahimipour
Endocrinol Diabetes Metab. 2023 May; 6(3): e410. Published online 2023 Feb 14. doi: 10.1002/edm2.410
PMCID:
PMC10164423
AbstractArticlePDF–917K
3.
The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
Zhi Lin, Jiao Liu, Fei Long, Rui Kang, Guido Kroemer, Daolin Tang, Minghua Yang
Nat Commun. 2022; 13: 7965. Published online 2022 Dec 27. doi: 10.1038/s41467-022-35707-2
PMCID:
PMC9794750
AbstractArticlePDF–8.9M
4.
Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells
Xiaohong Zhang, Stephen H. Wright
Int J Mol Sci. 2022 Feb; 23(3): 1472. Published online 2022 Jan 27. doi: 10.3390/ijms23031472
PMCID:
PMC8836179
AbstractArticlePDF–2.2M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer
Mitsukuni Suenaga, Marta Schirripa, Shu Cao, Wu Zhang, Dongyun Yang, Vincenzo Dadduzio, Lisa Salvatore, Beatrice Borelli, Filippo Pietrantonio, Yan Ning, Satoshi Okazaki, Martin D. Berger, Yuji Miyamoto, Roel Gopez, Jr, Afsaneh Barzi, Toshiharu Yamaguchi, Fotios Loupakis, Heinz-Josef Lenz
Eur J Cancer. Author manuscript; available in PMC 2020 Sep 17.
Published in final edited form as: Eur J Cancer. 2017 Nov; 86: 197–206. Published online 2017 Oct 6. doi: 10.1016/j.ejca.2017.08.033
PMCID:
PMC7497848
AbstractArticlePDF–1019K
7.
Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K
Marta Kantauskaitė, Anna Hucke, Moritz Reike, Sara Ahmed Eltayeb, Chuyan Xiao, Vivien Barz, Giuliano Ciarimboli
Int J Mol Sci. 2020 Jul; 21(14): 5157. Published online 2020 Jul 21. doi: 10.3390/ijms21145157
PMCID:
PMC7404265
AbstractArticlePDF–2.8M
8.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling
Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Science. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812
PMCID:
PMC7206793
AbstractArticlePDF–2.2M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO)
A. Gessner, J. König, M. F. Fromm
Sci Rep. 2018; 8: 6659. Published online 2018 Apr 27. doi: 10.1038/s41598-018-25139-8
PMCID:
PMC5923289
AbstractArticlePDF–1.4M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients
S Harrach, C Schmidt-Lauber, T Pap, H Pavenstädt, E Schlatter, E Schmidt, W E Berdel, U Schulze, B Edemir, S Jeromin, T Haferlach, G Ciarimboli, J Bertrand
Blood Cancer J. 2016 Sep; 6(9): e470. Published online 2016 Sep 16. doi: 10.1038/bcj.2016.79
PMCID:
PMC5056971
AbstractArticlePDF–574K
13.
Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients
Chen-Yue Qian, Yi Zheng, Ying Wang, Juan Chen, Jun-Yan Liu, Hong-Hao Zhou, Ji-Ye Yin, Zhao-Qian Liu
Chin J Cancer. 2016; 35(1): 85. Published online 2016 Sep 2. doi: 10.1186/s40880-016-0145-8
PMCID:
PMC5010769
AbstractArticlePDF–1.6M
14.
Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1
Lucy J. Martínez-Guerrero, Mark Morales, Sean Ekins, Stephen H. Wright
Mol Pharmacol. 2016 Sep; 90(3): 254–264. Published online 2016 Sep. doi: 10.1124/mol.116.105056
PMCID:
PMC4998666
AbstractArticlePDF–1.5M
15.
The multidrug transporter MATE1 sequesters OCs within an intracellular compartment that has no influence on OC secretion in renal proximal tubules
L. J. Martínez-Guerrero, K. K. Evans, W. H. Dantzler, S. H. Wright
Am J Physiol Renal Physiol. 2016 Jan 1; 310(1): F57–F67. Published online 2015 Nov 4. doi: 10.1152/ajprenal.00318.2015
PMCID:
PMC4675803
AbstractArticle
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
OCT2 and MATE1 Provide Bi-directional Agmatine Transport
Tate N. Winter, William F. Elmquist, Carolyn A. Fairbanks
Mol Pharm. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: Mol Pharm. 2011 Feb 7; 8(1): 133–142. Published online 2010 Dec 3. doi: 10.1021/mp100180a
PMCID:
PMC4589871
AbstractArticlePDF–1.2M
18.
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
Ligong Chen, Yan Shu, Xiaomin Liang, Eugene C. Chen, Sook Wah Yee, Arik A. Zur, Shuanglian Li, Lu Xu, Kayvan R. Keshari, Michael J. Lin, Huan-Chieh Chien, Youcai Zhang, Kari M. Morrissey, Jason Liu, Jonathan Ostrem, Noah S. Younger, John Kurhanewicz, Kevan M. Shokat, Kaveh Ashrafi, Kathleen M. Giacomini
Proc Natl Acad Sci U S A. 2014 Jul 8; 111(27): 9983–9988. Published online 2014 Jun 24. doi: 10.1073/pnas.1314939111
PMCID:
PMC4103324
AbstractArticlePDF–1.0M
19.
The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin
Sophie L. Stocker, Kari M. Morrissey, Sook Wah Yee, Richard A. Castro, Lu Xu, Amber Dahlin, Andrea H. Ramirez, Dan M. Roden, Russ A. Wilke, Cathy A. McCarty, Robert L. Davis, Claire M. Brett, Kathleen M. Giacomini
Clin Pharmacol Ther. Author manuscript; available in PMC 2014 Feb 1.
Published in final edited form as: Clin Pharmacol Ther. 2013 Feb; 93(2): 186–194. Published online 2012 Oct 17. doi: 10.1038/clpt.2012.210
PMCID:
PMC3671611
AbstractArticlePDF–2.7M
20.
Twelve Transmembrane Helices Form the Functional Core of Mammalian MATE1 (Multidrug and Toxin Extruder 1) Protein
Xiaohong Zhang, Xiao He, Joseph Baker, Florence Tama, Geoffrey Chang, Stephen H. Wright
J Biol Chem. 2012 Aug 10; 287(33): 27971–27982. Published online 2012 Jun 21. doi: 10.1074/jbc.M112.386979
PMCID:
PMC3431635
AbstractArticlePDF–4.6M

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