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Items: 1 to 20 of 84

1.
Ataxia‐telangiectasia‐mutated dependent phosphorylation of Artemis in response to DNA damage
Ling Chen, Tomohiro Morio, Yoshiyuki Minegishi, Shin‐Ichiro Nakada, Masayuki Nagasawa, Kenshi Komatsu, Luciana Chessa, Anna Villa, Daniele Lecis, Domenico Delia, Shuki Mizutani
Cancer Sci. 2005 Feb; 96(2): 134–141. Published online 2005 Feb 21. doi: 10.1111/j.1349-7006.2005.00019.x
PMCID:
PMC11158676
AbstractArticlePDF–271K
2.
Dynamics of the Artemis and DNA-PKcs Complex in the Repair of Double-Strand Breaks
Go Watanabe, Michael R. Lieber
J Mol Biol. Author manuscript; available in PMC 2023 Dec 15.
Published in final edited form as: J Mol Biol. 2022 Dec 15; 434(23): 167858. Published online 2022 Oct 19. doi: 10.1016/j.jmb.2022.167858
PMCID:
PMC9940633
AbstractArticlePDF–1023K
3.
Lentiviral Gene Therapy for Artemis-Deficient SCID
Morton J. Cowan, Jason Yu, Janelle Facchino, Carol Fraser-Browne, Ukina Sanford, Misako Kawahara, Jasmeen Dara, Janel Long-Boyle, Jess Oh, Wendy Chan, Shivali Chag, Lori Broderick, Deepak Chellapandian, Hélène Decaluwe, Catherine Golski, Diana Hu, Caroline Y. Kuo, Holly K. Miller, Aleksandra Petrovic, Robert Currier, Joan F. Hilton, Divya Punwani, Christopher C. Dvorak, Harry L. Malech, R. Scott McIvor, Jennifer M. Puck
N Engl J Med. Author manuscript; available in PMC 2023 Jan 29.
Published in final edited form as: N Engl J Med. 2022 Dec 22; 387(25): 2344–2355. doi: 10.1056/NEJMoa2206575
PMCID:
PMC9884487
AbstractArticlePDF–1.2M
4.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
5.
Structural analysis of the basal state of the Artemis:DNA-PKcs complex
Go Watanabe, Michael R Lieber, Dewight R Williams
Nucleic Acids Res. 2022 Jul 22; 50(13): 7697–7720. Published online 2022 Jul 8. doi: 10.1093/nar/gkac564
PMCID:
PMC9303282
AbstractArticlePDF–16M
6.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
7.
Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening
Antonella Falconieri, Giovanni Minervini, Federica Quaglia, Geppo Sartori, Silvio C. E. Tosatto
Cancers (Basel) 2022 Feb; 14(4): 1009. Published online 2022 Feb 17. doi: 10.3390/cancers14041009
PMCID:
PMC8869832
AbstractArticlePDF–1.1M
8.
Staring at the Naked Goddess: Unraveling the Structure and Reactivity of Artemis Endonuclease Interacting with a DNA Double Strand
Cécilia Hognon, Antonio Monari
Molecules. 2021 Jul; 26(13): 3986. Published online 2021 Jun 29. doi: 10.3390/molecules26133986
PMCID:
PMC8271620
AbstractArticlePDF–2.3M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
Artemis‐dependent DNA double‐strand break formation at stalled replication forks
Junya Unno, Masatoshi Takagi, Jinhua Piao, Masataka Sugimoto, Fumiko Honda, Daisuke Maeda, Mitsuko Masutani, Tohru Kiyono, Fumiaki Watanabe, Tomohiro Morio, Hirobumi Teraoka, Shuki Mizutani
Cancer Sci. 2013 Jun; 104(6): 703–710. Published online 2013 Apr 15. doi: 10.1111/cas.12144
PMCID:
PMC7657233
AbstractArticlePDF–1.6M
11.
Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model
Jennings Luu, Les Kallestad, Thanh Hoang, Dominik Lewandowski, Zhiqian Dong, Seth Blackshaw, Krzysztof Palczewski
Hum Mol Genet. 2020 Aug 29; 29(15): 2611–2624. Published online 2020 Jul 21. doi: 10.1093/hmg/ddaa158
PMCID:
PMC7471509
AbstractArticlePDF–2.5M
12.
Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features
Md Fazlul Karim, Shanshan Liu, Adrian R. Laciak, Leah Volk, Mary Koszelak-Rosenblum, Michael R. Lieber, Mousheng Wu, Rory Curtis, Nian N. Huang, Grant Carr, Guangyu Zhu
J Biol Chem. 2020 Aug 28; 295(35): 12368–12377. Published online 2020 Jun 23. doi: 10.1074/jbc.RA120.014136
PMCID:
PMC7458816
AbstractArticlePDF–2.6M
13.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair
Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen
Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794
PMCID:
PMC7050103
AbstractArticlePDF–1.8M
16.
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets
Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge
Mol Cell. Author manuscript; available in PMC 2019 Dec 4.
Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008
PMCID:
PMC6892393
AbstractArticlePDF–1.7M
17.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
18.
Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma
Yu Zheng, Baihui Li, Jian Wang, Yanjuan Xiong, Kaiyuan Wang, Ying Qi, Houfang Sun, Lei Wu, Lili Yang
Clin Epigenetics. 2018; 10: 129. Published online 2018 Oct 22. doi: 10.1186/s13148-018-0562-4
PMCID:
PMC6198372
AbstractArticlePDF–3.1M
19.
TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining
Ajinkya S Kawale, Konstantin Akopiants, Kristoffer Valerie, Brian Ruis, Eric A Hendrickson, Shar-yin N Huang, Yves Pommier, Lawrence F Povirk
Nucleic Acids Res. 2018 Sep 28; 46(17): 8926–8939. Published online 2018 Aug 3. doi: 10.1093/nar/gky694
PMCID:
PMC6158748
AbstractArticlePDF–3.2M
20.
DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development
Yin‐Li Zhang, Long‐Wen Zhao, Jue Zhang, Rongrong Le, Shu‐Yan Ji, Chuan Chen, Yawei Gao, Dali Li, Shaorong Gao, Heng‐Yu Fan
EMBO J. 2018 Sep 14; 37(18): e98981. Published online 2018 Aug 14. doi: 10.15252/embj.201898981
PMCID:
PMC6138440
AbstractArticlePDF–3.2M

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