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Select item 103751861.

From Phenomenon to Essence: A Newly Involved lncRNA Kcnq1ot1 Protective Mechanism of Bone Marrow Mesenchymal Stromal Cells in Liver Cirrhosis

Hanjing Zhangdi, Yanan Jiang, Yang Gao, Shuang Li, Ruiling Xu, Jing Shao, Jingyang Liu, Ying Hu, Xu Zhang, Xiaoyu Zhang, Lei Zhao, Jihan Qi, Xinyu Geng, Shizhu Jin

Adv Sci (Weinh) 2023 Jul; 10(21): 2206758. Published online 2023 Jun 6. doi: 10.1002/advs.202206758

PMCID:: PMC10375186

Abstract Article PDF–8.2M

Select item 99113972.

Long non-coding RNA KCNQ1OT1 alleviates postmenopausal osteoporosis by modulating miR-421-3p/mTOR axis

Ziyu Wang, Hengshuo Zhang, Qinghui Li, Lu Zhang, Lu Chen, Hongliang Wang, Yunzhen Chen

Sci Rep. 2023; 13: 2333. Published online 2023 Feb 9. doi: 10.1038/s41598-023-29546-4

PMCID:: PMC9911397

Abstract Article PDF–18M

Select item 89179133.

Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1

Andrya J. Durr, Quincy A. Hathaway, Amina Kunovac, Andrew D. Taylor, Mark V. Pinti, Saira Rizwan, Danielle L. Shepherd, Chris C. Cook, Garrett K. Fink, John M. Hollander

Am J Physiol Cell Physiol. 2022 Mar 1; 322(3): C482–C495. Published online 2022 Feb 2. doi: 10.1152/ajpcell.00446.2021

PMCID:: PMC8917913

Abstract Article

Select item 77239924.

LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis

Xiao-Hua Yu, Wen-Yi Deng, Jiao-Jiao Chen, Xiao-Dan Xu, Xian-Xia Liu, Lei Chen, Meng-Wen Shi, Qi-Xian Liu, Min Tao, Kun Ren

Cell Death Dis. 2020 Dec; 11(12): 1043. Published online 2020 Dec 9. doi: 10.1038/s41419-020-03263-6

PMCID:: PMC7723992

Abstract Article PDF–4.8M

Select item 66889595.

LncRNA-induced spread of Polycomb controlled by genome architecture, RNA abundance, and CpG island DNA

Megan D. Schertzer, Keean C.A. Braceros, Joshua Starmer, Rachel E. Cherney, David M. Lee, Gabriela Salazar, Megan Justice, Steven R. Bischoff, Dale O. Cowley, Pablo Ariel, Mark J. Zylka, Jill M. Dowen, Terry Magnuson, J. Mauro Calabrese

Mol Cell. Author manuscript; available in PMC 2020 Aug 8.

Published in final edited form as: Mol Cell. 2019 Aug 8; 75(3): 523–537.e10. Published online 2019 Jun 27. doi: 10.1016/j.molcel.2019.05.028

PMCID:: PMC6688959

Abstract Article PDF–3.3M

Select item 65161676.

KCNQ1OT1 promotes autophagy by regulating miR‐200a/FOXO3/ATG7 pathway in cerebral ischemic stroke

Shijia Yu, Mingjun Yu, Xin He, Lulu Wen, Zhongqi Bu, Juan Feng

Aging Cell. 2019 Jun; 18(3): e12940. Published online 2019 Apr 3. doi: 10.1111/acel.12940

PMCID:: PMC6516167

Abstract Article PDF–1.5M

Select item 64518867.

miR-126 regulates glycogen trophoblast proliferation and DNA methylation in the murine placenta

Abhijeet Sharma, Lauretta A. Lacko, Lissenya B. Argueta, Michael D. Glendinning, Heidi Stuhlmann

Dev Biol. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Dev Biol. 2019 May 1; 449(1): 21–34. Published online 2019 Feb 14. doi: 10.1016/j.ydbio.2019.01.019

PMCID:: PMC6451886

Abstract Article PDF–2.5M

Select item 63344728.

The long non-coding RNA Kcnq1ot1 controls maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region

Oriella Andresini, Marianna Nicoletta Rossi, Francesca Matteini, Stefano Petrai, Tiziana Santini, Rossella Maione

Epigenetics Chromatin. 2019; 12: 8. Published online 2019 Jan 16. doi: 10.1186/s13072-019-0253-1

PMCID:: PMC6334472

Abstract Article PDF–1.5M

Select item 63224149.

The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting

Chen-Cheng Lee, Shih-Huan Peng, Li Shen, Chung-Fan Lee, Ting-Huei Du, Ming-Lun Kang, Guo-Liang Xu, Anup K. Upadhyay, Xiaodong Cheng, Yu-Ting Yan, Yi Zhang, Li-Jung Juan

Mol Cell. Author manuscript; available in PMC 2019 Jan 7.

Published in final edited form as: Mol Cell. 2017 Oct 5; 68(1): 89–103.e7. Published online 2017 Sep 21. doi: 10.1016/j.molcel.2017.08.025

PMCID:: PMC6322414

Abstract Article PDF–2.6M

Select item 615522310.

Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy

Fan Yang, Ying Qin, Jie Lv, Yueqiu Wang, Hui Che, Xi Chen, Yanan Jiang, Anqi Li, Xi Sun, Er Yue, Long Ren, Yang Li, Yunlong Bai, Lihong Wang

Cell Death Dis. 2018 Oct; 9(10): 1000. Published online 2018 Sep 24. doi: 10.1038/s41419-018-1029-4

PMCID:: PMC6155223

Abstract Article PDF–5.1M

Select item 610503311.

Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage

Aaron B. Bogutz, Rosemary Oh-McGinnis, Karen J. Jacob, Rita Ho-Lau, Ting Gu, Marina Gertsenstein, Andras Nagy, Louis Lefebvre

PLoS Genet. 2018 Aug; 14(8): e1007587. Published online 2018 Aug 10. doi: 10.1371/journal.pgen.1007587

PMCID:: PMC6105033

Abstract Article PDF–16M

Select item 605202012.

Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

Saqib S. Sachani, Lauren S. Landschoot, Liyue Zhang, Carlee R. White, William A. MacDonald, Michael C. Golding, Mellissa R. W. Mann

Nat Commun. 2018; 9: 2795. Published online 2018 Jul 18. doi: 10.1038/s41467-018-05208-2

PMCID:: PMC6052020

Abstract Article PDF–2.1M

Select item 545083613.

Blocked transcription through KvDMR1 results in absence of methylation and gene silencing resembling Beckwith-Wiedemann syndrome

Vir B. Singh, Sirinapa Sribenja, Kayla E. Wilson, Kristopher M. Attwood, Joanna C. Hillman, Shilpa Pathak, Michael J. Higgins

Development. 2017 May 15; 144(10): 1820–1830. doi: 10.1242/dev.145136

PMCID:: PMC5450836

Abstract Article

Select item 450023614.

Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c

Shun-ichiro Asahara, Hiroaki Etoh, Hiroyuki Inoue, Kyoko Teruyama, Yuki Shibutani, Yuka Ihara, Yukina Kawada, Alberto Bartolome, Naoko Hashimoto, Tomokazu Matsuda, Maki Koyanagi-Kimura, Ayumi Kanno, Yushi Hirota, Tetsuya Hosooka, Kazuaki Nagashima, Wataru Nishimura, Hiroshi Inoue, Michihiro Matsumoto, Michael J. Higgins, Kazuki Yasuda, Nobuya Inagaki, Susumu Seino, Masato Kasuga, Yoshiaki Kido

Proc Natl Acad Sci U S A. 2015 Jul 7; 112(27): 8332–8337. Published online 2015 Jun 22. doi: 10.1073/pnas.1422104112

PMCID:: PMC4500236

Abstract Article PDF–1.1M

Select item 433337915.

Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain

Bryant M. Schultz, Gwendolyn A. Gallicio, Matteo Cesaroni, Lena N. Lupey, Nora Engel

Nucleic Acids Res. 2015 Jan 30; 43(2): 745–759. Published online 2014 Dec 24. doi: 10.1093/nar/gku1324

PMCID:: PMC4333379

Abstract Article PDF–2.3M

Select item 407640316.

In Vitro Culture Increases the Frequency of Stochastic Epigenetic Errors at Imprinted Genes in Placental Tissues from Mouse Concepti Produced Through Assisted Reproductive Technologies

Eric de Waal, Winifred Mak, Sondra Calhoun, Paula Stein, Teri Ord, Christopher Krapp, Christos Coutifaris, Richard M. Schultz, Marisa S. Bartolomei

Biol Reprod. 2014 Feb; 90(2): 22. Published online 2013 Dec 11. doi: 10.1095/biolreprod.113.114785

PMCID:: PMC4076403

Abstract Article PDF–2.2M

Select item 396496417.

The Vertebrate Genome Annotation browser 10 years on

Jennifer L. Harrow, Charles A. Steward, Adam Frankish, James G. Gilbert, Jose M. Gonzalez, Jane E. Loveland, Jonathan Mudge, Dan Sheppard, Mark Thomas, Stephen Trevanion, Laurens G. Wilming

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D771–D779. Published online 2013 Dec 6. doi: 10.1093/nar/gkt1241

PMCID:: PMC3964964

Abstract Article PDF–11M

Select item 388278718.

Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus

He Zhang, Michael J. Zeitz, Hong Wang, Beibei Niu, Shengfang Ge, Wei Li, Jiuwei Cui, Guanjun Wang, Guanxiang Qian, Michael J. Higgins, Xianqun Fan, Andrew R. Hoffman, Ji-Fan Hu

J Cell Biol. 2014 Jan 6; 204(1): 61–75. doi: 10.1083/jcb.201304152

PMCID:: PMC3882787

Abstract Article PDF–3.6M

Select item 381708019.

The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region

Louis Lefebvre, Lynn Mar, Aaron Bogutz, Rosemary Oh-McGinnis, Mohammad Mandegar, Jana Paderova, Marina Gertsenstein, Jeremy A. Squire, Andras Nagy

Hum Mol Genet. Author manuscript; available in PMC 2013 Nov 4.

Published in final edited form as: Hum Mol Genet. 2009 Nov 15; 18(22): 4255–4267. Published online 2009 Aug 14. doi: 10.1093/hmg/ddp379

PMCID:: PMC3817080

Abstract Article PDF–1.6M

Select item 351647420.

Differentiation-Driven Nucleolar Association of the Mouse Imprinted Kcnq1 Locus

Andrew M. Fedoriw, J. Mauro Calabrese, Weipeng Mu, Della Yee, Terry Magnuson

G3 (Bethesda) 2012 Dec; 2(12): 1521–1528. Published online 2012 Dec 1. doi: 10.1534/g3.112.004226

PMCID:: PMC3516474

Abstract Article PDF–1.3M

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