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Select item 102089581.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 99611292.

Glucose 6-P Dehydrogenase Overexpression Improves Aging-Induced Endothelial Dysfunction in Aorta from Mice: Role of Arginase II

Eva Serna, Maria D Mauricio, Teresa San-Miguel, Sol Guerra-Ojeda, David Verdú, Alicia Valls, Coralie Arc-Chagnaud, Adrián De la Rosa, José Viña

Int J Mol Sci. 2023 Feb; 24(4): 3622. Published online 2023 Feb 11. doi: 10.3390/ijms24043622

PMCID:: PMC9961129

Abstract Article PDF–2.8M

Select item 96038603.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 92670664.

G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle

Aiwen Jiang, Hongyun Guo, Xiaoyu Jiang, Jingli Tao, Wangjun Wu, Honglin Liu

Int J Mol Sci. 2022 Jul; 23(13): 7425. Published online 2022 Jul 4. doi: 10.3390/ijms23137425

PMCID:: PMC9267066

Abstract Article PDF–5.5M

Select item 83866845.

G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of Plasmodium berghei Infection

Haoan Yi, Weiyang Jiang, Fang Yang, Fan Li, Yirong Li, Wenjing Zhu, Qing Li, Syed Hassam Fakhar, Yaming Cao, Lan Luo, Wen Zhang, Yongshu He

Front Immunol. 2021; 12: 719189. Published online 2021 Aug 11. doi: 10.3389/fimmu.2021.719189

PMCID:: PMC8386684

Abstract Article PDF–16M

Select item 82381566.

Glucose-6-phosphate dehydrogenase deficiency contributes to metabolic abnormality and pulmonary hypertension

Mathews Valuparampil Varghese, Joel James, Olga Rafikova, Ruslan Rafikov

Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1; 320(4): L508–L521. Published online 2021 Jan 27. doi: 10.1152/ajplung.00165.2020

PMCID:: PMC8238156

Abstract Article

Select item 79887617.

G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases

Vidhi Dhagia, Atsushi Kitagawa, Christina Jacob, Connie Zheng, Angelo D’Alessandro, John G. Edwards, Petra Rocic, Rakhee Gupte, Sachin A. Gupte

Am J Physiol Heart Circ Physiol. 2021 Mar 1; 320(3): H999–H1016. Published online 2021 Jan 8. doi: 10.1152/ajpheart.00488.2020

PMCID:: PMC7988761

Abstract Article

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78555069.

NF-κB inducing kinase maintains T cell metabolic fitness in antitumor immunity

Meidi Gu, Xiaofei Zhou, Jee Hyung Sohn, Lele Zhu, Zuliang Jie, Jin-Young Yang, Xiaofeng Zheng, Xiaoping Xie, Jie Yang, Yaoyao Shi, Hans D Brightbill, Jae Bum Kim, Jing Wang, Xuhong Cheng, Shao-Cong Sun

Nat Immunol. Author manuscript; available in PMC 2021 Jul 4.

Published in final edited form as: Nat Immunol. 2021 Feb; 22(2): 193–204. Published online 2021 Jan 4. doi: 10.1038/s41590-020-00829-6

Correction in:: Nat Immunol. 2021 Feb 11

PMCID:: PMC7855506

Abstract Article PDF–3.2M

Select item 747443710.

Glucose-6-phosphate dehydrogenase increases Ca²⁺ currents by interacting with Ca_v1.2 and reducing intrinsic inactivation of the L-type calcium channel

Rakhee Gupte, Vidhi Dhagia, Petra Rocic, Rikuo Ochi, Sachin A. Gupte

Am J Physiol Heart Circ Physiol. 2020 Jul 1; 319(1): H144–H158. Published online 2020 May 22. doi: 10.1152/ajpheart.00727.2019

PMCID:: PMC7474437

Abstract Article

Select item 741599111.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 719148612.

Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation

Sachindra Raj Joshi, Atsushi Kitagawa, Christina Jacob, Ryota Hashimoto, Vidhi Dhagia, Amrit Ramesh, Connie Zheng, Hui Zhang, Allan Jordan, Ian Waddell, Jane Leopold, Cheng-Jun Hu, Ivan F. McMurtry, Angelo D’Alessandro, Kurt R. Stenmark, Sachin A. Gupte

Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1; 318(4): L773–L786. Published online 2020 Mar 11. doi: 10.1152/ajplung.00001.2020

PMCID:: PMC7191486

Abstract Article

Select item 705268013.

Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension

Ryota Hashimoto, Gregg M. Lanier, Vidhi Dhagia, Sachindra R. Joshi, Allan Jordan, Ian Waddell, Rubin Tuder, Kurt R. Stenmark, Michael S. Wolin, Ivan F. McMurtry, Sachin A. Gupte

Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1; 318(2): L386–L401. Published online 2020 Jan 8. doi: 10.1152/ajplung.00327.2019

PMCID:: PMC7052680

Abstract Article

Select item 667406814.

Neuroprotection by Transgenic Expression of Glucose-6-Phosphate Dehydrogenase in Dopaminergic Nigrostriatal Neurons of Mice

Rebeca Mejías, Javier Villadiego, C. Oscar Pintado, Pablo J. Vime, Lin Gao, Juan J. Toledo-Aral, Miriam Echevarría, José López-Barneo

J Neurosci. 2006 Apr 26; 26(17): 4500–4508. doi: 10.1523/JNEUROSCI.0122-06.2006

PMCID:: PMC6674068

Abstract Article PDF–1.0M

Select item 660240715.

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma

Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe

Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050

PMCID:: PMC6602407

Abstract Article PDF–3.5M

Select item 629804016.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 626277717.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 624418318.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 623213719.

REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice

Cristina Gontan, Hegias Mira-Bontenbal, Aristea Magaraki, Catherine Dupont, Tahsin Stefan Barakat, Eveline Rentmeester, Jeroen Demmers, Joost Gribnau

Nat Commun. 2018; 9: 4752. Published online 2018 Nov 12. doi: 10.1038/s41467-018-07060-w

PMCID:: PMC6232137

Abstract Article PDF–5.2M

Select item 609753320.

Endotoxemia down-regulates bone marrow lymphopoiesis but stimulates myelopoiesis: the effect of G6PD deficiency

Rachna Chandra, Erika Villanueva, Eleonora Feketova, George W. Machiedo, György Haskó, Edwin A. Deitch, Zoltán Spolarics

J Leukoc Biol. Author manuscript; available in PMC 2018 Aug 17.

Published in final edited form as: J Leukoc Biol. 2008 Jun; 83(6): 1541–1550. Published online 2008 Mar 19. doi: 10.1189/jlb.1207838

PMCID:: PMC6097533

Abstract Article PDF–1.5M

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