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Items: 1 to 20 of 120

1.
mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms
Yusuf Ali, Celso E Gomez-Sanchez, Maria Plonczynski, Aniko Naray-Fejes-Toth, Geza Fejes-Toth, Elise P Gomez-Sanchez
Endocrinology. 2024 Apr; 165(4): bqae015. Published online 2024 Feb 7. doi: 10.1210/endocr/bqae015
PMCID:
PMC10887451
AbstractArticle
2.
IL-4 activates ULK1/Atg9a/Rab9 in asthma, NLRP3 inflammasomes, and Golgi fragmentation by increasing autophagy flux and mitochondrial oxidative stress
Chang Xu, Yilan Song, Wanting Liu, Ruobai Liu, Qiaoyun Bai, Liangchang Li, Chongyang Wang, Guanghai Yan
Redox Biol. 2024 May; 71: 103090. Published online 2024 Feb 15. doi: 10.1016/j.redox.2024.103090
PMCID:
PMC10878789
AbstractArticlePDF–20M
3.
Endurance Exercise Training Mitigates Diastolic Dysfunction in Diabetic Mice Independent of Phosphorylation of Ulk1 at S555
Yuntian Guan, Mei Zhang, Christie Lacy, Soham Shah, Frederick H. Epstein, Zhen Yan
Int J Mol Sci. 2024 Jan; 25(1): 633. Published online 2024 Jan 3. doi: 10.3390/ijms25010633
PMCID:
PMC10779281
AbstractArticlePDF–2.9M
4.
Phosphorylation of phase‐separated p62 bodies by ULK1 activates a redox‐independent stress response
Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu‐Hirota, Ritsuko Arai, Elena Ryzhii, Manabu Abe, Tomoaki Koga, Hozumi Motohashi, Mitsuyoshi Nakao, Kenji Sakimura, Arata Horii, Satoshi Waguri, Yoshinobu Ichimura, Nobuo N Noda, Masaaki Komatsu
EMBO J. 2023 Jul; 42(14): e113349. Published online 2023 Jun 12. doi: 10.15252/embj.2022113349
PMCID:
PMC10350833
AbstractArticlePDF–4.4M
5.
Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart
Jihoon Nah, Akihiro Shirakabe, Risa Mukai, Peiyong Zhai, Eun Ah Sung, Andreas Ivessa, Wataru Mizushima, Yasuki Nakada, Toshiro Saito, Chengchen Hu, Yong Keun Jung, Junichi Sadoshima
Cardiovasc Res. 2022 Aug; 118(12): 2638–2651. Published online 2022 Jan 9. doi: 10.1093/cvr/cvac003
PMCID:
PMC10144728
AbstractArticlePDF–2.0M
6.
Activation of eIF4E‐binding‐protein‐1 rescues mTORC1‐induced sarcopenia by expanding lysosomal degradation capacity
Elisa M. Crombie, Seonyoung Kim, Stuart Adamson, Han Dong, Tzu‐Chiao Lu, Yiju Wu, Yajun Wu, Yotam Levy, Nolan Stimple, Wing Moon R. Lam, Hwee Weng D. Hey, Dominic J. Withers, Ao‐Lin Hsu, Boon Huat Bay, Julien Ochala, Shih‐Yin Tsai
J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 198–213. Published online 2022 Nov 17. doi: 10.1002/jcsm.13121
PMCID:
PMC9891956
AbstractArticlePDF–4.2M
7.
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA
Laura S. Kremer, Lyuba V. Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F. Chinnery, Nils-Göran Larsson
PLoS Genet. 2023 Jan; 19(1): e1010573. Published online 2023 Jan 6. doi: 10.1371/journal.pgen.1010573
PMCID:
PMC9851501
AbstractArticlePDF–1.4M
8.
Autophagy protein ULK1 interacts with and regulates SARM1 during axonal injury
Harry M. C. Choi, Yun Li, Delwin Suraj, Ru-Ching Hsia, Chinmoy Sarkar, Junfang Wu, Marta M. Lipinski
Proc Natl Acad Sci U S A. 2022 Nov 22; 119(47): e2203824119. Published online 2022 Nov 14. doi: 10.1073/pnas.2203824119
PMCID:
PMC9704737
AbstractArticlePDF–4.5M
9.
Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function
Matthew P. Harris, Quan J. Zhang, Cole T. Cochran, Jessica Ponce, Sean Alexander, Ana Kronemberger, Jordan D. Fuqua, Yuan Zhang, Ranan Fattal, Tyler Harper, Matthew L. Murry, Chad E. Grueter, E. Dale Abel, Vitor A. Lira
Autophagy. 2022; 18(9): 2161–2177. Published online 2022 Feb 1. doi: 10.1080/15548627.2021.2022289
PMCID:
PMC9466614
AbstractArticlePDF–6.8M
10.
TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen
EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777
PMCID:
PMC9289709
AbstractArticlePDF–2.3M
11.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
12.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
13.
The combination of nuclear receptor NR1D1 and ULK1 promotes mitophagy in adipocytes to ameliorate obesity
Bo Yu, Jin-Bao Pan, Fei-Yue Yu
Adipocyte. 2022; 11(1): 202–212. Published online 2022 Apr 11. doi: 10.1080/21623945.2022.2060719
PMCID:
PMC9009922
AbstractArticlePDF–1.7M
14.
Deletion of Ulk1 inhibits neointima formation by enhancing KAT2A/GCN5-mediated acetylation of TUBA/α-tubulin in vivo
Changhan Ouyang, Jian Li, Xiaoxu Zheng, Jing Mu, Gloria Torres, Qilong Wang, Ming-Hui Zou, Zhonglin Xie
Autophagy. 2021; 17(12): 4305–4322. Published online 2021 May 14. doi: 10.1080/15548627.2021.1911018
PMCID:
PMC8726707
AbstractArticlePDF–8.5M
15.
ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3
Yufeng Zhang, Sheng Zhang, Yi Wang, Zhiqiang Yang, Zhe Chen, Nengqiao Wen, Min Yang, Zan Huang, Yuanlong Xie, Lin Cai
Oxid Med Cell Longev. 2021; 2021: 2896674. Published online 2021 Nov 15. doi: 10.1155/2021/2896674
PMCID:
PMC8608530
AbstractArticlePDF–4.3M
16.
STING protects against cardiac dysfunction and remodelling by blocking autophagy
Rui Xiong, Ning Li, Lei Chen, Wei Wang, Bo Wang, Wenyang Jiang, Qing Geng
Cell Commun Signal. 2021; 19: 109. Published online 2021 Nov 8. doi: 10.1186/s12964-021-00793-0
PMCID:
PMC8576910
AbstractArticlePDF–4.2M
17.
Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle
Joshua C. Drake, Rebecca J. Wilson, Di Cui, Yuntian Guan, Mondira Kundu, Mei Zhang, Zhen Yan
Front Physiol. 2021; 12: 732308. Published online 2021 Sep 30. doi: 10.3389/fphys.2021.732308
PMCID:
PMC8514673
AbstractArticlePDF–990K
18.
Porcine Hemagglutinating Encephalomyelitis Virus Triggers Neural Autophagy Independently of ULK1
Zi Li, Feng Gao, Yungang Lan, Jiyu Guan, Jing Zhang, Huijun Lu, Kui Zhao, Wenqi He
J Virol. 2021 Oct; 95(19): e00851-21. Prepublished online 2021 Jul 21. Published online 2021 Sep 9. doi: 10.1128/JVI.00851-21
PMCID:
PMC8428410
AbstractArticlePDF–3.6M
19.
Phosphorylation of ULK1 serine 746 dictates ATG5-independent autophagy
Xin Wen, Daniel J. Klionsky
Autophagy. 2020; 16(9): 1557–1558. Published online 2020 Jun 16. doi: 10.1080/15548627.2020.1780844
PMCID:
PMC8386595
AbstractArticlePDF–205K
20.
The regulatory effect of acetylation of HMGN2 and H3K27 on pyocyanin‐induced autophagy in macrophages by affecting Ulk1 transcription
Yu Du, Hongjun Guo, Lijuan Guo, Junming Miao, Hongyu Ren, Keyun Liu, Laibin Ren, Jinchen He, Xiaoying Wang, Junli Chen, Jingyu Li, Yi Wang, Ji Wang, Ning Huang
J Cell Mol Med. 2021 Aug; 25(15): 7524–7537. Published online 2021 Jul 18. doi: 10.1111/jcmm.16788
PMCID:
PMC8335688
AbstractArticlePDF–1.8M

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