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Items: 1 to 20 of 130

1.
Prognostic impact of immunohistochemical biomarkers in diffuse large B‐cell lymphoma in the rituximab era
Ritsuko Seki, Koichi Ohshima, Tomoaki Fujisaki, Naokuni Uike, Fumio Kawano, Hisashi Gondo, Shigeyoshi Makino, Tetsuya Eto, Yukiyoshi Moriuchi, Fumihiro Taguchi, Tomohiko Kamimura, Hiroyuki Tsuda, Ryosuke Ogawa, Kazuya Shimoda, Kiyoshi Yamashita, Keiko Suzuki, Hitoshi Suzushima, Kunihiro Tsukazaki, Masakazu Higuchi, Atae Utsunomiya, Masahiro Iwahashi, Yutaka Imamura, Kazuo Tamura, Junji Suzumiya, Minoru Yoshida, Yasunobu Abe, Tadashi Matsumoto, Takashi Okamura
Cancer Sci. 2009 Oct; 100(10): 1842–1847. Published online 2009 Jul 1. doi: 10.1111/j.1349-7006.2009.01268.x
PMCID:
PMC11158565
AbstractArticlePDF–458K
2.
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency
IRF4 International Consortium
Sci Immunol. Author manuscript; available in PMC 2024 Jan 30.
Published in final edited form as: Sci Immunol. 2023 Jan 20; 8(79): eade7953. Published online 2023 Jan 20. doi: 10.1126/sciimmunol.ade7953
PMCID:
PMC10825898
AbstractArticlePDF–2.3M
3.
Transcriptional reprogramming by mutated IRF4 in lymphoma
Nikolai Schleussner, Pierre Cauchy, Vedran Franke, Maciej Giefing, Oriol Fornes, Naveen Vankadari, Salam A. Assi, Mariantonia Costanza, Marc A. Weniger, Altuna Akalin, Ioannis Anagnostopoulos, Thomas Bukur, Marco G. Casarotto, Frederik Damm, Oliver Daumke, Benjamin Edginton-White, J. Christof M. Gebhardt, Michael Grau, Stephan Grunwald, Martin-Leo Hansmann, Sylvia Hartmann, Lionel Huber, Eva Kärgel, Simone Lusatis, Daniel Noerenberg, Nadine Obier, Ulrich Pannicke, Anja Fischer, Anja Reisser, Andreas Rosenwald, Klaus Schwarz, Srinivasan Sundararaj, Andre Weilemann, Wiebke Winkler, Wendan Xu, Georg Lenz, Klaus Rajewsky, Wyeth W. Wasserman, Peter N. Cockerill, Claus Scheidereit, Reiner Siebert, Ralf Küppers, Rudolf Grosschedl, Martin Janz, Constanze Bonifer, Stephan Mathas
Nat Commun. 2023; 14: 6947. Published online 2023 Nov 7. doi: 10.1038/s41467-023-41954-8
PMCID:
PMC10630337
AbstractArticlePDF–4.9M
4.
Human inborn errors of immunity associated with IRF4
Romane Thouenon, Sven Kracker
Front Immunol. 2023; 14: 1236889. Published online 2023 Sep 22. doi: 10.3389/fimmu.2023.1236889
PMCID:
PMC10556498
AbstractArticlePDF–1.1M
5.
Emerging entities: high-grade/large B-cell lymphoma with 11q aberration, large B-cell lymphoma with IRF4 rearrangement, and new molecular subgroups in large B-cell lymphomas. A report of the 2022 EA4HP/SH lymphoma workshop
Leticia Quintanilla-Martinez, Camille Laurent, Lorinda Soma, Siok-Bian Ng, Fina Climent, Sarah L. Ondrejka, Alberto Zamo, Andrew Wotherspoon, Laurence de Leval, Stefan Dirnhofer, Lorenzo Leoncini
Virchows Arch. 2023; 483(3): 281–298. Published online 2023 Aug 9. doi: 10.1007/s00428-023-03590-x
PMCID:
PMC10541818
AbstractArticlePDF–3.9M
6.
A neomorphic mutation in the interferon activation domain of IRF4 causes a dominant primary immunodeficiency
Romane Thouenon, Loïc Chentout, Nidia Moreno-Corona, Lucie Poggi, Emilia Puig Lombardi, Benedicte Hoareau, Yohann Schmitt, Chantal Lagresle-Peyrou, Jacinta Bustamante, Isabelle André, Marina Cavazzana, Anne Durandy, Jean-Laurent Casanova, Lionel Galicier, Jehane Fadlallah, Alain Fischer, Sven Kracker
J Exp Med. 2023 Jun 5; 220(6): e20221292. Published online 2023 Mar 14. doi: 10.1084/jem.20221292
PMCID:
PMC10037104
AbstractArticlePDF–6.4M
7.
Prevalence of IRF4 rearrangement in large B-cell lymphomas of the Waldeyer’s ring in adults
Sebastian Streich, Leonie Frauenfeld, Franziska Otto, Barbara Mankel, Irina Bonzheim, Falko Fend, Leticia Quintanilla-Martinez
Virchows Arch. 2023; 482(3): 551–560. Published online 2023 Feb 22. doi: 10.1007/s00428-023-03516-7
PMCID:
PMC10033557
AbstractArticlePDF–1.8M
8.
IRF4 as a novel target involved in malignant transformation of oral submucous fibrosis into oral squamous cell carcinoma
Li Meng, Yucheng Jiang, Jiawen You, Panpan Zhao, Weiguang Liu, Na Zhao, Zhichun Yu, Junqing Ma
Sci Rep. 2023; 13: 2775. Published online 2023 Feb 16. doi: 10.1038/s41598-023-29936-8
PMCID:
PMC9935854
AbstractArticlePDF–11M
9.
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity
Dennis Das Gupta, Christoph Paul, Nadine Samel, Maria Bieringer, Daniel Staudenraus, Federico Marini, Hartmann Raifer, Lisa Menke, Lea Hansal, Bärbel Camara, Edith Roth, Patrick Daum, Michael Wanzel, Marco Mernberger, Andrea Nist, Uta-Maria Bauer, Frederik Helmprobst, Malte Buchholz, Katrin Roth, Lorenz Bastian, Alina M. Hartmann, Claudia Baldus, Koichi Ikuta, Andreas Neubauer, Andreas Burchert, Hans-Martin Jäck, Matthias Klein, Tobias Bopp, Thorsten Stiewe, Axel Pagenstecher, Michael Lohoff
Cell Death Differ. 2022 Nov; 29(11): 2163–2176. Published online 2022 Apr 22. doi: 10.1038/s41418-022-01005-z
PMCID:
PMC9613660
AbstractArticlePDF–5.8M
10.
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells
Jillian A. Bristol, Joshua Brand, Makoto Ohashi, Mark R. Eichelberg, Alejandro Casco, Scott E. Nelson, Mitchell Hayes, James C. Romero-Masters, Dana C. Baiu, Jenny E. Gumperz, Eric C. Johannsen, Huy Q. Dinh, Shannon C. Kenney
PLoS Pathog. 2022 Apr; 18(4): e1010453. Published online 2022 Apr 26. doi: 10.1371/journal.ppat.1010453
PMCID:
PMC9041801
AbstractArticlePDF–6.4M
11.
Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements
Leonie Frauenfeld, Natalia Castrejon-de-Anta, Joan Enric Ramis-Zaldivar, Sebastian Streich, Julia Salmerón-Villalobos, Franziska Otto, Annika Katharina Mayer, Julia Steinhilber, Magda Pinyol, Barbara Mankel, Colleen Ramsower, Irina Bonzheim, Falko Fend, Lisa M. Rimsza, Itziar Salaverria, Elias Campo, Olga Balagué, Leticia Quintanilla-Martinez
Blood Adv. 2022 Apr 12; 6(7): 2361–2372. Published online 2022 Apr 7. doi: 10.1182/bloodadvances.2021006034
PMCID:
PMC9006278
AbstractArticlePDF–2.9M
12.
The molecular basis for the development of adult T‐cell leukemia/lymphoma in patients with an IRF4K59R mutation
Srinivasan Sundararaj, Sandali Seneviratne, Simon J Williams, Anselm Enders, Marco G. Casarotto
Protein Sci. 2022 Apr; 31(4): 787–796. Published online 2022 Feb 15. doi: 10.1002/pro.4260
PMCID:
PMC8927869
AbstractArticlePDF–2.1M
13.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
14.
Impact of hypoxia on the pathogenesis and therapy resistance in multiple myeloma
Sho Ikeda, Hiroyuki Tagawa
Cancer Sci. 2021 Oct; 112(10): 3995–4004. Published online 2021 Aug 9. doi: 10.1111/cas.15087
PMCID:
PMC8486179
AbstractArticlePDF–510K
15.
Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms
Tongwu Zhang, Jiyeon Choi, Ramile Dilshat, Berglind Ósk Einarsdóttir, Michael A. Kovacs, Mai Xu, Michael Malasky, Salma Chowdhury, Kristine Jones, D. Timothy Bishop, Alisa M. Goldstein, Mark M. Iles, Maria Teresa Landi, Matthew H. Law, Jianxin Shi, Eiríkur Steingrímsson, Kevin M. Brown
Am J Hum Genet. 2021 Sep 2; 108(9): 1631–1646. Published online 2021 Jul 21. doi: 10.1016/j.ajhg.2021.06.018
PMCID:
PMC8456160
AbstractArticlePDF–3.9M
16.
Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4
Alessandro Agnarelli, Kamel El Omari, Ramona Duman, Armin Wagner, Erika J. Mancini
Acta Crystallogr F Struct Biol Commun. 2021 Jul 1; 77(Pt 7): 202–207. Published online 2021 Jun 29. doi: 10.1107/S2053230X21006506
PMCID:
PMC8248823
AbstractArticlePDF–795K
17.
Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells
Ashni A. Vora, Phoebe K. Mondala, Caitlin Costello, A. Robert MacLeod, Leslie A. Crews
STAR Protoc. 2021 Jun 18; 2(2): 100565. Published online 2021 May 27. doi: 10.1016/j.xpro.2021.100565
PMCID:
PMC8176358
AbstractArticlePDF–3.5M
18.
Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting miR-1228-3p/IRF4 Axis
Zhi-Min Deng, Fang-Fang Dai, Quan Zhou, Yan-Xiang Cheng
BMC Cancer. 2021; 21: 583. Published online 2021 May 21. doi: 10.1186/s12885-021-08331-4
PMCID:
PMC8140416
AbstractArticlePDF–2.7M
19.
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients
Carole Le Coz, David N. Nguyen, Chun Su, Brian E. Nolan, Amanda V. Albrecht, Suela Xhani, Di Sun, Benjamin Demaree, Piyush Pillarisetti, Caroline Khanna, Francis Wright, Peixin Amy Chen, Samuel Yoon, Amy L. Stiegler, Kelly Maurer, James P. Garifallou, Amy Rymaszewski, Steven H. Kroft, Timothy S. Olson, Alix E. Seif, Gerald Wertheim, Struan F.A. Grant, Linda T. Vo, Jennifer M. Puck, Kathleen E. Sullivan, John M. Routes, Viktoria Zakharova, Anna Shcherbina, Anna Mukhina, Natasha L. Rudy, Anna C.E. Hurst, T. Prescott Atkinson, Titus J. Boggon, Hakon Hakonarson, Adam R. Abate, Joud Hajjar, Sarah K. Nicholas, James R. Lupski, James Verbsky, Ivan K. Chinn, Michael V. Gonzalez, Andrew D. Wells, Alex Marson, Gregory M.K. Poon, Neil Romberg
J Exp Med. 2021 Jul 5; 218(7): e20201750. Published online 2021 May 5. doi: 10.1084/jem.20201750
PMCID:
PMC8105723
AbstractArticlePDF–5.9M
20.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M

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