PMC Links for GEO Profiles (Select 33125046) - PMC

Tetsuhiro Ueda, Toshihide Takeuchi, Nobuhiro Fujikake, Mari Suzuki, Eiko N. Minakawa, Morio Ueyama, Yuzo Fujino, Nobuyuki Kimura, Seiichi Nagano, Akio Yokoseki, Osamu Onodera, Hideki Mochizuki, Toshiki Mizuno, Keiji Wada, Yoshitaka Nagai

Acta Neuropathol Commun. 2024; 12: 20. Published online 2024 Feb 4. doi: 10.1186/s40478-024-01729-8

PMCID:: PMC10840176

Abstract Article PDF–2.9M

Select item 107809545.

TDP-43 impairs sleep in Drosophila through Ataxin-2–dependent metabolic disturbance

Alexandra E. Perlegos, Jaclyn Durkin, Samuel J. Belfer, Anyara Rodriguez, Oksana Shcherbakova, Kristen Park, Jenny Luong, Nancy M. Bonini, Matthew S. Kayser

Sci Adv. 2024 Jan 12; 10(2): eadj4457. Published online 2024 Jan 10. doi: 10.1126/sciadv.adj4457

PMCID:: PMC10780954

Abstract Article PDF–2.1M

Select item 105882186.

Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits

R. Keating Godfrey, Eric Alsop, Reed T. Bjork, Brijesh S. Chauhan, Hillary C. Ruvalcaba, Jerry Antone, Lauren M. Gittings, Allison F. Michael, Christi Williams, Grace Hala’ufia, Alexander D. Blythe, Megan Hall, Rita Sattler, Kendall Van Keuren-Jensen, Daniela C. Zarnescu

Acta Neuropathol Commun. 2023; 11: 168. Published online 2023 Oct 20. doi: 10.1186/s40478-023-01656-0

PMCID:: PMC10588218

Abstract Article PDF–30M

Select item 105538327.

TDP-43 pathology in Drosophila induces glial-cell type specific toxicity that can be ameliorated by knock-down of SF2/SRSF1

Sarah Krupp, Isabel Hubbard, Oliver Tam, Gale M. Hammell, Josh Dubnau

PLoS Genet. 2023 Sep; 19(9): e1010973. Published online 2023 Sep 25. doi: 10.1371/journal.pgen.1010973

PMCID:: PMC10553832

Abstract Article PDF–3.0M

Select item 105338678.

Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

Marta Marzullo, Giulia Romano, Claudia Pellacani, Federico Riccardi, Laura Ciapponi, Fabian Feiguin

Cell Death Discov. 2023; 9: 357. Published online 2023 Sep 27. doi: 10.1038/s41420-023-01643-3

PMCID:: PMC10533867

Abstract Article PDF–2.2M

Select item 105237619.

Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

Marina L. Garcia-Vaquero, Marjorie Heim, Barbara Flix, Marcelo Pereira, Lucile Palin, Tânia M. Marques, Francisco R. Pinto, Javier de Las Rivas, Aaron Voigt, Florence Besse, Margarida Gama-Carvalho

BMC Genomics. 2023; 24: 576. Published online 2023 Sep 27. doi: 10.1186/s12864-023-09562-4

PMCID:: PMC10523761

Abstract Article PDF–3.2M

Select item 1039167510.

The tardigrade Dsup protein enhances radioresistance in Drosophila melanogaster and acts as an unspecific repressor of transcription

Mikhail Zarubin, Talyana Azorskaya, Olga Kuldoshina, Sergey Alekseev, Semen Mitrofanov, Elena Kravchenko

iScience. 2023 Jul 21; 26(7): 106998. Published online 2023 May 29. doi: 10.1016/j.isci.2023.106998

PMCID:: PMC10391675

Abstract Article PDF–3.0M

Select item 1023277511.

Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies

Stefania Santarelli, Chiara Londero, Alessia Soldano, Carlotta Candelaresi, Leonardo Todeschini, Luisa Vernizzi, Paola Bellosta

Front Neurosci. 2023; 17: 1082047. Published online 2023 May 18. doi: 10.3389/fnins.2023.1082047

PMCID:: PMC10232775

Abstract Article PDF–2.4M

Select item 1017543312.

C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD

Pedro Ervilha Pereira, Nika Schuermans, Antoon Meylemans, Pontus LeBlanc, Lauren Versluys, Katie E. Copley, Jack D. Rubien, Christopher Altheimer, Myra Peetermans, Elke Debackere, Olivier Vanakker, Sandra Janssens, Jonathan Baets, Kristof Verhoeven, Martin Lammens, Sofie Symoens, Boel De Paepe, Sami J. Barmada, James Shorter, Jan L. De Bleecker, Elke Bogaert, Bart Dermaut

Acta Neuropathol. 2023; 145(6): 793–814. Published online 2023 Mar 31. doi: 10.1007/s00401-023-02565-1

PMCID:: PMC10175433

Abstract Article PDF–6.1M

Select item 1012192313.

Repetitive elements in aging and neurodegeneration

Katie E. Copley, James Shorter

Trends Genet. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Trends Genet. 2023 May; 39(5): 381–400. Published online 2023 Mar 17. doi: 10.1016/j.tig.2023.02.008

PMCID:: PMC10121923

Abstract Article PDF–935K

Select item 1010573614.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0