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Select item 111181771.

The First Defined Null Allele of the Notch Regulator, a Suppressor of Deltex: Uncovering Its Novel Roles in Drosophila melanogaster Oogenesis

Marian B. Wilkin, Rory Whiteford, Tanveer Akbar, Samira Hosseini-Alghaderi, Raluca Revici, Ann-Marie Carbery, Martin Baron

Biomolecules. 2024 May; 14(5): 522. Published online 2024 Apr 26. doi: 10.3390/biom14050522

PMCID:: PMC11118177

Abstract Article PDF–22M

Select item 109457072.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 108684003.

Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains

Hideyuki Shimizu, Samira Hosseini-Alghaderi, Simon A. Woodcock, Martin Baron

J Cell Biol. 2024 May 6; 223(5): e202211041. Published online 2024 Feb 15. doi: 10.1083/jcb.202211041

PMCID:: PMC10868400

Abstract Article PDF–5.9M

Select item 103988944.

The E3 ligase Poe promotes Pericentrin degradation

Brian J. Galletta, Ramya Varadarajan, Carey J. Fagerstrom, Bing Yang, Karen Plevock Haase, Katherine McJunkin, Nasser M. Rusan

Mol Biol Cell. 2023 Aug 1; 34(9): br15. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-11-0534

PMCID:: PMC10398894

Abstract Article PDF–4.7M

Select item 101057365.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 91015076.

Endocytosis at the Crossroad of Polarity and Signaling Regulation: Learning from Drosophila melanogaster and Beyond

Fani Papagiannouli

Int J Mol Sci. 2022 May; 23(9): 4684. Published online 2022 Apr 23. doi: 10.3390/ijms23094684

PMCID:: PMC9101507

Abstract Article PDF–3.6M

Select item 89616087.

E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans

Raluca Revici, Samira Hosseini-Alghaderi, Fabienne Haslam, Rory Whiteford, Martin Baron

Biomolecules. 2022 Feb; 12(2): 224. Published online 2022 Jan 27. doi: 10.3390/biom12020224

PMCID:: PMC8961608

Abstract Article PDF–2.0M

Select item 89086868.

Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway

Björn Schnute, Hideyuki Shimizu, Marvin Lyga, Martin Baron, Thomas Klein

BMC Biol. 2022; 20: 65. Published online 2022 Mar 10. doi: 10.1186/s12915-022-01245-y

PMCID:: PMC8908686

Abstract Article PDF–10M

Select item 87036579.

Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination

Qing Zhang, Jin Jiang

Int J Mol Sci. 2021 Dec; 22(24): 13338. Published online 2021 Dec 11. doi: 10.3390/ijms222413338

PMCID:: PMC8703657

Abstract Article PDF–1.5M

Select item 866448610.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 861025411.

The ZO-1 protein Polychaetoid as an upstream regulator of the Hippo pathway in Drosophila

Qingliang Sang, Gang Wang, David B. Morton, Hui Wu, Baotong Xie

PLoS Genet. 2021 Nov; 17(11): e1009894. Published online 2021 Nov 8. doi: 10.1371/journal.pgen.1009894

PMCID:: PMC8610254

Abstract Article PDF–3.5M

Select item 846605812.

The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation

Judith Hounjet, Marc Vooijs

Biomolecules. 2021 Sep; 11(9): 1369. Published online 2021 Sep 16. doi: 10.3390/biom11091369

PMCID:: PMC8466058

Abstract Article PDF–2.2M

Select item 789552613.

Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription

Sherzod A Tokamov, Ting Su, Anne Ullyot, Richard G Fehon

eLife. 2021; 10: e62326. Published online 2021 Feb 8. doi: 10.7554/eLife.62326

PMCID:: PMC7895526

Abstract Article PDF–10M

Select item 775459714.

Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery

Miriam Baeumers, Kristina Ruhnau, Thomas Breuer, Hendrik Pannen, Bastian Goerlich, Anna Kniebel, Sebastian Haensch, Stefanie Weidtkamp-Peters, Lutz Schmitt, Thomas Klein

BMC Biol. 2020; 18: 200. Published online 2020 Dec 22. doi: 10.1186/s12915-020-00933-x