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Items: 1 to 20 of 46

1.
Maintenance of proteostasis by Drosophila Rer1 is essential for competitive cell survival and Myc-driven overgrowth
Pranab Kumar Paul, Shruti Umarvaish, Shivani Bajaj, Rishana Farin S., Hrudya Mohan, Wim Annaert, Varun Chaudhary
PLoS Genet. 2024 Feb; 20(2): e1011171. Published online 2024 Feb 26. doi: 10.1371/journal.pgen.1011171
PMCID:
PMC10919865
AbstractArticlePDF–9.8M
2.
The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response
Rima Naït-Saïdi, Aymeric Chartier, Emmanuelle Abgueguen, Philippe Guédat, Martine Simonelig
Open Biol. 2023 Apr; 13(4): 230008. Published online April 12, 2023. doi: 10.1098/rsob.230008
PMCID:
PMC10090878
AbstractArticlePDF–1.6M
3.
New Drosophila models to uncover the intrinsic and extrinsic factors that mediate the toxicity of the human prion protein
Ryan R. Myers, Jonatan Sanchez-Garcia, Daniel C. Leving, Richard G. Melvin, Pedro Fernandez-Funez
Dis Model Mech. 2022 Apr 1; 15(4): dmm049184. Published online 2022 May 4. doi: 10.1242/dmm.049184
PMCID:
PMC9093039
AbstractArticle
4.
The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function
Marianthi Kiparaki, Chaitali Khan, Virginia Folgado-Marco, Jacky Chuen, Panagiotis Moulos, Nicholas E Baker
eLife. 2022; 11: e71705. Published online 2022 Feb 18. doi: 10.7554/eLife.71705
PMCID:
PMC8933008
AbstractArticlePDF–17M
5.
Xrp1 and Irbp18 trigger a feed-forward loop of proteotoxic stress to induce the loser status
Paul F. Langton, Michael E. Baumgartner, Remi Logeay, Eugenia Piddini
PLoS Genet. 2021 Dec; 17(12): e1009946. Published online 2021 Dec 16. doi: 10.1371/journal.pgen.1009946
PMCID:
PMC8675655
AbstractArticlePDF–4.4M
6.
Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes
Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis
G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349
PMCID:
PMC8664486
AbstractArticlePDF–3.1M
7.
The transcription factor Xrp1 is required for PERK-mediated antioxidant gene induction in Drosophila
Brian Brown, Sahana Mitra, Finnegan D Roach, Deepika Vasudevan, Hyung Don Ryoo
eLife. 2021; 10: e74047. Published online 2021 Oct 4. doi: 10.7554/eLife.74047
PMCID:
PMC8514241
AbstractArticlePDF–13M
8.
Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth
Gongping Sun, Xun Austin Ding, Yewubdar Argaw, Xiaoran Guo, Denise J. Montell
Nat Commun. 2020; 11: 5726. Published online 2020 Nov 12. doi: 10.1038/s41467-020-19068-2
PMCID:
PMC7664998
AbstractArticlePDF–6.8M
9.
Proteotoxic stress is a driver of the loser status and of cell competition
Michael E. Baumgartner, Michael P. Dinan, Paul F. Langton, Iwo Kucinski, Eugenia Piddini
Nat Cell Biol. Author manuscript; available in PMC 2021 Jul 25.
Published in final edited form as: Nat Cell Biol. 2021 Feb 1; 23(2): 136–146. Published online 2021 Jan 25. doi: 10.1038/s41556-020-00627-0
PMCID:
PMC7116823
AbstractArticlePDF–9.3M
10.
Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition
Carles Recasens-Alvarez, Cyrille Alexandre, Joanna Kirkpatrick, Hisashi Nojima, David J. Huels, Ambrosius P. Snijders, Jean-Paul Vincent
Nat Cell Biol. Author manuscript; available in PMC 2021 Jul 25.
Published in final edited form as: Nat Cell Biol. 2021 Feb 1; 23(2): 127–135. Published online 2021 Jan 25. doi: 10.1038/s41556-020-00626-1
PMCID:
PMC7116740
AbstractArticlePDF–6.0M
11.
CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans
Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang
Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119
PMCID:
PMC6961578
AbstractArticlePDF–3.6M
12.
Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis
Richard G Melvin, Nicole Lamichane, Essi Havula, Krista Kokki, Charles Soeder, Corbin D Jones, Ville Hietakangas
eLife. 2018; 7: e40841. Published online 2018 Nov 27. doi: 10.7554/eLife.40841
PMCID:
PMC6301794
AbstractArticlePDF–4.8M
13.
A regulatory response to ribosomal protein mutations controls translation, growth, and cell competition
Chang-Hyun Lee, Marianthi Kiparaki, Jorge Blanco, Virginia Folgado, Zhejun Ji, Amit Kumar, Gerard Rimesso, Nicholas. E. Baker
Dev Cell. Author manuscript; available in PMC 2019 Aug 20.
Published in final edited form as: Dev Cell. 2018 Aug 20; 46(4): 456–469.e4. Published online 2018 Aug 2. doi: 10.1016/j.devcel.2018.07.003
Correction in:
Dev Cell. 2018 Sep 24; 46(6): 807.
PMCID:
PMC6261318
AbstractArticlePDF–2.9M
14.
The integrated stress response regulates BMP signalling through effects on translation
Elke Malzer, Caia S. Dominicus, Joseph E. Chambers, Jennifer A. Dickens, Souradip Mookerjee, Stefan J. Marciniak
BMC Biol. 2018; 16: 34. Published online 2018 Apr 3. doi: 10.1186/s12915-018-0503-x
PMCID:
PMC5881181
AbstractArticlePDF–3.7M
15.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
AbstractArticlePDF–3.2M
16.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
AbstractArticlePDF–4.0M
17.
Small chaperons and autophagy protected neurons from necrotic cell death
Ye Lei, Kai Liu, Lin Hou, Lianggong Ding, Yuhong Li, Lei Liu
Sci Rep. 2017; 7: 5650. Published online 2017 Jul 18. doi: 10.1038/s41598-017-05995-6
PMCID:
PMC5515951
AbstractArticlePDF–2.8M
18.
Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation
Taiichi Tsuyama, Asako Tsubouchi, Tadao Usui, Hiromi Imamura, Tadashi Uemura
J Cell Biol. 2017 Mar 6; 216(3): 815–834. doi: 10.1083/jcb.201604065
PMCID:
PMC5346966
AbstractArticlePDF–3.3M
19.
mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster
Gildas Lepennetier, Francesco Catania
G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231
PMCID:
PMC4889658
AbstractArticlePDF–1.5M
20.
The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model
Y Demay, J Perochon, S Szuplewski, B Mignotte, S Gaumer
Cell Death Dis. 2014 Oct; 5(10): e1452. Published online 2014 Oct 9. doi: 10.1038/cddis.2014.403
PMCID:
PMC4649510
AbstractArticlePDF–4.0M

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