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Items: 1 to 20 of 80

1.
Mitochondrial energy state controls AMPK-mediated foraging behavior in C. elegans
Anežka Vodičková, Annika Müller-Eigner, Chidozie N. Okoye, Andrew P. Bischer, Jacob Horn, Shon A. Koren, Nada Ahmed Selim, Andrew P. Wojtovich
Sci Adv. 2024 Apr 19; 10(16): eadm8815. Published online 2024 Apr 17. doi: 10.1126/sciadv.adm8815
PMCID:
PMC11023558
AbstractArticlePDF–4.4M
2.
Cell non-autonomous control of autophagy and metabolism by glial cells
Melissa G. Metcalf, Samira Monshietehadi, Arushi Sahay, Jenni Durieux, Ashley E. Frakes, Martina Velichkovska, Cesar Mena, Amelia Farinas, Melissa Sanchez, Andrew Dillin
iScience. 2024 Apr 19; 27(4): 109354. Published online 2024 Feb 28. doi: 10.1016/j.isci.2024.109354
PMCID:
PMC10946330
AbstractArticlePDF–7.6M
3.
Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity
Yong Yu, Shihong M Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu, Bentian Jing, Qian Zhao, David M Sabatini, Monther Abu-Remaileh, Sung Yun Jung, Meng C Wang
eLife. 2024; 13: e85214. Published online 2024 Jan 19. doi: 10.7554/eLife.85214
PMCID:
PMC10876212
AbstractArticlePDF–5.9M
4.
Maternal aging increases offspring adult body size via transmission of donut-shaped mitochondria
Runshuai Zhang, Jinan Fang, Ting Qi, Shihao Zhu, Luxia Yao, Guicun Fang, Yunsheng Li, Xiao Zang, Weina Xu, Wanyu Hao, Shouye Liu, Dan Yang, Di Chen, Jian Yang, Xianjue Ma, Lianfeng Wu
Cell Res. 2023 Nov; 33(11): 821–834. Published online 2023 Jul 27. doi: 10.1038/s41422-023-00854-8
PMCID:
PMC10624822
AbstractArticlePDF–5.2M
5.
Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans
Elite Possik, Laura-Lee Klein, Perla Sanjab, Ruyuan Zhu, Laurence Côté, Ying Bai, Dongwei Zhang, Howard Sun, Anfal Al-Mass, Abel Oppong, Rasheed Ahmad, Alex Parker, S.R. Murthy Madiraju, Fahd Al-Mulla, Marc Prentki
Nat Commun. 2023; 14: 5214. Published online 2023 Aug 25. doi: 10.1038/s41467-023-40857-y
PMCID:
PMC10457390
AbstractArticlePDF–3.3M
6.
A transcriptional cofactor regulatory network for the C. elegans intestine
Brent B Horowitz, Shivani Nanda, Albertha J M Walhout
G3 (Bethesda) 2023 Jul; 13(7): jkad096. Published online 2023 Apr 29. doi: 10.1093/g3journal/jkad096
PMCID:
PMC10320766
AbstractArticlePDF–1.9M
7.
A proton-inhibited DEG/ENaC ion channel maintains neuronal ionstasis and promotes neuronal survival under stress
Dionysia Petratou, Martha Gjikolaj, Eva Kaulich, William Schafer, Nektarios Tavernarakis
iScience. 2023 Jul 21; 26(7): 107117. Published online 2023 Jun 14. doi: 10.1016/j.isci.2023.107117
PMCID:
PMC10320524
AbstractArticlePDF–8.3M
8.
Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity
Wenming Huang, Chun Kew, Stephanie de Alcantara Fernandes, Anna Löhrke, Lynn Han, Constantinos Demetriades, Adam Antebi
Nat Aging. 2022; 2(9): 796–808. Published online 2022 Sep 19. doi: 10.1038/s43587-022-00275-z
PMCID:
PMC10154236
AbstractArticlePDF–17M
9.
Germline stem cell integrity and quiescence are controlled by an AMPK-dependent neuronal trafficking pathway
Christopher Wong, Pratik Kadekar, Elena Jurczak, Richard Roy
PLoS Genet. 2023 Apr; 19(4): e1010716. Published online 2023 Apr 14. doi: 10.1371/journal.pgen.1010716
PMCID:
PMC10132661
AbstractArticlePDF–2.4M
10.
Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations
Merly C. Vogt, Oliver Hobert
Sci Adv. 2023 Apr; 9(14): eade1817. Published online 2023 Apr 7. doi: 10.1126/sciadv.ade1817
PMCID:
PMC10081852
AbstractArticlePDF–3.2M
11.
A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes
Gholamreza Fazeli, Roni Levin-Konigsberg, Michael C. Bassik, Christian Stigloher, Ann M. Wehman
Curr Biol. Author manuscript; available in PMC 2024 Feb 27.
Published in final edited form as: Curr Biol. 2023 Feb 27; 33(4): 607–621.e7. Published online 2023 Jan 17. doi: 10.1016/j.cub.2022.12.041
PMCID:
PMC9992095
AbstractArticlePDF–2.5M
12.
Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1‐imidazoline receptor
Dominic F. Bennett, Anita Goyala, Cyril Statzer, Charles W. Beckett, Alexander Tyshkovskiy, Vadim N. Gladyshev, Collin Y. Ewald, João Pedro de Magalhães
Aging Cell. 2023 Feb; 22(2): e13774. Published online 2023 Jan 20. doi: 10.1111/acel.13774
PMCID:
PMC9924948
AbstractArticlePDF–4.3M
13.
Intracellular lipid surveillance by small G protein geranylgeranylation
Abigail Watterson, Lexus Tatge, Naureen Wajahat, Sonja L. B. Arneaud, Rene Solano Fonseca, Shaghayegh T. Beheshti, Patrick Metang, Melina Mihelakis, Kielen R. Zuurbier, Chase D. Corley, Ishmael Dehghan, Jeffrey G. McDonald, Peter M. Douglas
Nature. Author manuscript; available in PMC 2023 Jan 30.
Published in final edited form as: Nature. 2022 May; 605(7911): 736–740. Published online 2022 May 18. doi: 10.1038/s41586-022-04729-7
PMCID:
PMC9885440
AbstractArticlePDF–4.2M
14.
A new AMPK isoform mediates glucose-restriction induced longevity non-cell autonomously by promoting membrane fluidity
Jin-Hyuck Jeong, Jun-Seok Han, Youngae Jung, Seung-Min Lee, So-Hyun Park, Mooncheol Park, Min-Gi Shin, Nami Kim, Mi Sun Kang, Seokho Kim, Kwang-Pyo Lee, Ki-Sun Kwon, Chun-A. Kim, Yong Ryoul Yang, Geum-Sook Hwang, Eun-Soo Kwon
Nat Commun. 2023; 14: 288. Published online 2023 Jan 18. doi: 10.1038/s41467-023-35952-z
PMCID:
PMC9849402
AbstractArticlePDF–2.5M
15.
Unscheduled epigenetic modifications cause genome instability and sterility through aberrant R-loops following starvation
Bing Sun, McLean Sherrin, Richard Roy
Nucleic Acids Res. 2023 Jan 11; 51(1): 84–98. Published online 2022 Dec 12. doi: 10.1093/nar/gkac1155
PMCID:
PMC9841415
AbstractArticlePDF–5.4M
16.
Isocitrate Dehydrogenase Alpha-1 Modulates Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans
Zhi-Han Lin, Shun-Ya Chang, Wen-Chi Shen, Yen-Hung Lin, Chiu-Lun Shen, Sin-Bo Liao, Yu-Chun Liu, Chang-Shi Chen, Tsui-Ting Ching, Horng-Dar Wang
Int J Mol Sci. 2023 Jan; 24(1): 612. Published online 2022 Dec 29. doi: 10.3390/ijms24010612
PMCID:
PMC9820670
AbstractArticlePDF–2.9M
17.
Stimulation of RAS-dependent ROS signaling extends longevity by modulating a developmental program of global gene expression
Robyn Branicky, Ying Wang, Arman Khaki, Ju-Ling Liu, Maximilian Kramer-Drauberg, Siegfried Hekimi
Sci Adv. 2022 Dec; 8(48): eadc9851. Published online 2022 Nov 30. doi: 10.1126/sciadv.adc9851
PMCID:
PMC9710873
AbstractArticlePDF–2.2M
18.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shating Long, Mingliang Zhang, Jin-Wei Feng, Xiaoyan Wei, Yan-Hui Liu, Baoding Zhang, Jianfeng Wu, Cixiong Zhang, Wenhua Lian, Teng Ma, Xiao Tian, Qi Qu, Yaxin Yu, Jinye Xiong, Dong-Tai Liu, Zhenhua Wu, Mingxia Zhu, Changchuan Xie, Yaying Wu, Zheni Xu, Chunyan Yang, Junjie Chen, Guohong Huang, Qingxia He, Xi Huang, Lei Zhang, Xiufeng Sun, Qingfeng Liu, Abdul Ghafoor, Fu Gui, Kaili Zheng, Wen Wang, Zhi-Chao Wang, Yong Yu, Qingliang Zhao, Shu-Yong Lin, Zhi-Xin Wang, Hai-Long Piao, Xianming Deng, Sheng-Cai Lin
Nat Metab. 2022; 4(10): 1369–1401. Published online 2022 Oct 10. doi: 10.1038/s42255-022-00640-7
PMCID:
PMC9584815
AbstractArticlePDF–9.0M
19.
Deregulation of Mitochondrial Calcium Handling Due to Presenilin Loss Disrupts Redox Homeostasis and Promotes Neuronal Dysfunction
Kerry C. Ryan, Jocelyn T. Laboy, Kenneth R. Norman
Antioxidants (Basel) 2022 Sep; 11(9): 1642. Published online 2022 Aug 24. doi: 10.3390/antiox11091642
PMCID:
PMC9495597
AbstractArticlePDF–2.2M
20.
Nutrient sensing pathways regulating adult reproductive diapause in C. elegans
Moriah Eustice, Daniel Konzman, Jeff M. Reece, Salil Ghosh, Jhullian Alston, Tyler Hansen, Andy Golden, Michelle R. Bond, Lara K. Abramowitz, John A. Hanover
PLoS One. 2022; 17(9): e0274076. Published online 2022 Sep 16. doi: 10.1371/journal.pone.0274076
PMCID:
PMC9480990
AbstractArticlePDF–2.1M

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