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Items: 1 to 20 of 88

1.
Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress
Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini
Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1
PMCID:
PMC10891154
AbstractArticlePDF–2.6M
2.
Severe anemia caused by dominant mutations in Krüppel-like factor 1 (KLF1)
Klaudia Kulczynska-Figurny, James J. Bieker, Miroslawa Siatecka
Mutat Res Rev Mutat Res. Author manuscript; available in PMC 2023 May 20.
Published in final edited form as: Mutat Res Rev Mutat Res. 2020 Oct-Dec; 786: 108336. Published online 2020 Oct 9. doi: 10.1016/j.mrrev.2020.108336
PMCID:
PMC10199782
AbstractArticlePDF–960K
3.
EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release
Kaustav Mukherjee, James J. Bieker
Cell Rep. Author manuscript; available in PMC 2023 Jan 26.
Published in final edited form as: Cell Rep. 2022 Dec 20; 41(12): 111830. doi: 10.1016/j.celrep.2022.111830
PMCID:
PMC9879271
AbstractArticlePDF–4.0M
4.
Zkscan3 affects erythroblast development by regulating the transcriptional activity of GATA1 and KLF1 in mice
Zixuan Li, Binjie Sheng, Tingting Zhang, Tian Wang, Dan Chen, Gangli An, Xingbing Wang, Huimin Meng, Lin Yang
J Mol Histol. 2022; 53(2): 423–436. Published online 2021 Dec 23. doi: 10.1007/s10735-021-10052-8
PMCID:
PMC9117376
AbstractArticlePDF–4.3M
5.
A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis
Chun-Hao Hung, Tung-Liang Lee, Anna Yu-Szu Huang, Kang-Chung Yang, Yu-Chiau Shyu, Shau-Ching Wen, Mu-Jie Lu, Shinsheng Yuan, Che-Kun James Shen
Int J Mol Sci. 2021 Aug; 22(15): 8024. Published online 2021 Jul 27. doi: 10.3390/ijms22158024
PMCID:
PMC8347936
AbstractArticlePDF–4.4M
6.
EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis
Kaustav Mukherjee, Li Xue, Antanas Planutis, Merlin Nithya Gnanapragasam, Andrew Chess, James J Bieker
eLife. 2021; 10: e61070. Published online 2021 Feb 11. doi: 10.7554/eLife.61070
PMCID:
PMC7932694
AbstractArticlePDF–6.4M
7.
Negative Regulation of the Differentiation of Flk2− CD34− LSK Hematopoietic Stem Cells by EKLF/KLF1
Chun-Hao Hung, Keh-Yang Wang, Yae-Huei Liou, Jing-Ping Wang, Anna Yu-Szu Huang, Tung-Liang Lee, Si-Tse Jiang, Nah-Shih Liao, Yu-Chiau Shyu, Che-Kun James Shen
Int J Mol Sci. 2020 Nov; 21(22): 8448. Published online 2020 Nov 10. doi: 10.3390/ijms21228448
PMCID:
PMC7697791
AbstractArticlePDF–2.7M
8.
POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression
Bjorg Gudmundsdottir, Kristbjorn O. Gudmundsson, Kimberly D. Klarmann, Satyendra K. Singh, Lei Sun, Shweta Singh, Yang Du, Vincenzo Coppola, Luke Stockwin, Nhu Nguyen, Lino Tessarollo, Leifur Thorsteinsson, Olafur E. Sigurjonsson, Sveinn Gudmundsson, Thorunn Rafnar, John F. Tisdale, Jonathan R. Keller
Cell Rep. Author manuscript; available in PMC 2020 Jun 18.
Published in final edited form as: Cell Rep. 2018 Jun 12; 23(11): 3236–3248. doi: 10.1016/j.celrep.2018.05.043
PMCID:
PMC7301966
AbstractArticlePDF–2.2M
9.
Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver
Tomoaki Ueda, Takafumi Yokota, Daisuke Okuzaki, Yoshihiro Uno, Tomoji Mashimo, Yoshiaki Kubota, Takao Sudo, Tomohiko Ishibashi, Yasuhiro Shingai, Yukiko Doi, Takayuki Ozawa, Ritsuko Nakai, Akira Tanimura, Michiko Ichii, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
Stem Cell Reports. 2019 Dec 10; 13(6): 992–1005. Published online 2019 Dec 5. doi: 10.1016/j.stemcr.2019.11.002
PMCID:
PMC6915804
AbstractArticlePDF–2.5M
10.
mTORC1 activity is essential for erythropoiesis and B cell lineage commitment
Natasha Malik, Karen M. Dunn, Jennifer Cassels, Jodie Hay, Christopher Estell, Owen J. Sansom, Alison M. Michie
Sci Rep. 2019; 9: 16917. Published online 2019 Nov 15. doi: 10.1038/s41598-019-53141-1
PMCID:
PMC6858379
AbstractArticlePDF–4.8M
11.
Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors
Melissa D. Ilsley, Stephen Huang, Graham W. Magor, Michael J. Landsberg, Kevin R. Gillinder, Andrew C. Perkins
BMC Genomics. 2019; 20: 417. Published online 2019 May 24. doi: 10.1186/s12864-019-5805-z
PMCID:
PMC6534859
AbstractArticlePDF–5.4M
12.
The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation
Ileana Cantú, Harmen J. G. van de Werken, Nynke Gillemans, Ralph Stadhouders, Steven Heshusius, Alex Maas, Fatemehsadat Esteghamat, Zeliha Ozgur, Wilfred F. J. van IJcken, Frank Grosveld, Marieke von Lindern, Sjaak Philipsen, Thamar B. van Dijk
PLoS One. 2019; 14(3): e0208659. Published online 2019 Mar 28. doi: 10.1371/journal.pone.0208659
PMCID:
PMC6438607
AbstractArticlePDF–2.7M
13.
Mutation in Erythroid Specific Transcription Factor KLF1 Causes Hereditary Spherocytosis in the Nan Hemolytic Anemia Mouse Model
Daniel P. Heruth, Troy Hawkins, Derek P. Logsdon, Margaret I. Gibson, Inna V. Sokolovsky, Ndona N. Nsumu, Stephanie L. Major, Barbara Fegley, Gerald M. Woods, Karen B. Lewing, Kathleen A. Neville, Kenneth Cornetta, Kenneth R. Peterson, Robert A. White
Genomics. Author manuscript; available in PMC 2019 Feb 26.
Published in final edited form as: Genomics. 2010 Nov; 96(5): 303–307. Published online 2010 Aug 5. doi: 10.1016/j.ygeno.2010.07.009
PMCID:
PMC6390478
AbstractArticlePDF–1.0M
14.
TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis
Diwash Acharya, Bernadette Nera, Zachary J. Milstone, Lauren Bourke, Yeonsoo Yoon, Jaime A. Rivera-Pérez, Chinmay M. Trivedi, Thomas G. Fazzio
Sci Rep. 2018; 8: 14908. Published online 2018 Oct 8. doi: 10.1038/s41598-018-33213-4
PMCID:
PMC6175934
AbstractArticlePDF–4.4M
15.
Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis
Danitza Nébor, Joel H. Graber, Steven L. Ciciotte, Raymond F. Robledo, Julien Papoin, Emily Hartman, Kevin R. Gillinder, Andrew C. Perkins, James J. Bieker, Lionel Blanc, Luanne L. Peters
Sci Rep. 2018; 8: 12793. Published online 2018 Aug 24. doi: 10.1038/s41598-018-30839-2
PMCID:
PMC6109071
AbstractArticlePDF–5.4M
16.
Deficiency in interferon type 1 receptor improves definitive erythropoiesis in Klf1 null mice
Maria Francesca Manchinu, Carla Brancia, Cristian Antonio Caria, Ester Musu, Susanna Porcu, Michela Simbula, Isadora Asunis, Lucia Perseu, Maria Serafina Ristaldi
Cell Death Differ. 2018 Mar; 25(3): 589–599. Published online 2017 Dec 11. doi: 10.1038/s41418-017-0003-5
PMCID:
PMC5864211
AbstractArticlePDF–6.8M
17.
Krüppel-like factors compete for promoters and enhancers to fine-tune transcription
Melissa D. Ilsley, Kevin R. Gillinder, Graham W. Magor, Stephen Huang, Timothy L. Bailey, Merlin Crossley, Andrew C. Perkins
Nucleic Acids Res. 2017 Jun 20; 45(11): 6572–6588. Published online 2017 May 24. doi: 10.1093/nar/gkx441
PMCID:
PMC5499887
AbstractArticlePDF–7.1M
18.
Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch
Laura J. Norton, Samantha Hallal, Elizabeth S. Stout, Alister P. W. Funnell, Richard C. M. Pearson, Merlin Crossley, Kate G. R. Quinlan
Sci Rep. 2017; 7: 3137. Published online 2017 Jun 9. doi: 10.1038/s41598-017-03289-5
PMCID:
PMC5466599
AbstractArticlePDF–4.7M
19.
Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia
Hiroki Higashiyama, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru, Yukio Saijoh, Masami Kanai-Azuma, Yoshiakira Kanai
Development. 2017 May 15; 144(10): 1906–1917. doi: 10.1242/dev.147512
PMCID:
PMC5450840
AbstractArticle
20.
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability
Kevin R. Gillinder, Melissa D. Ilsley, Danitza Nébor, Ravi Sachidanandam, Mathieu Lajoie, Graham W. Magor, Michael R. Tallack, Timothy Bailey, Michael J. Landsberg, Joel P. Mackay, Michael W. Parker, Luke A. Miles, Joel H. Graber, Luanne L. Peters, James J. Bieker, Andrew C. Perkins
Nucleic Acids Res. 2017 Feb 17; 45(3): 1130–1143. Published online 2016 Nov 24. doi: 10.1093/nar/gkw1014
PMCID:
PMC5388391
AbstractArticlePDF–4.3M

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