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Select item 112969141.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 111598782.

Co‐overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial–mesenchymal transition

Ahmed S. Sultan, Hassan Brim, Zaki A. Sherif

Cancer Sci. 2008 Feb; 99(2): 272–279. Published online 2008 Feb 6. doi: 10.1111/j.1349-7006.2007.00685.x

PMCID:: PMC11159878

Abstract Article PDF–299K

Select item 110949503.

PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility

Nan Jing, Xinxing Du, Yu Liang, ZhenKeke Tao, Shijia Bao, Huixiang Xiao, Baijun Dong, Wei-Qiang Gao, Yu-Xiang Fang

J Exp Clin Cancer Res. 2024; 43: 144. Published online 2024 May 15. doi: 10.1186/s13046-024-03064-1

Correction in:: J Exp Clin Cancer Res. 2024; 43: 167.

PMCID:: PMC11094950

Abstract Article PDF–15M

Select item 110146624.

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia

Tobias Suske, Helena Sorger, Gabriele Manhart, Frank Ruge, Nicole Prutsch, Mark W. Zimmerman, Thomas Eder, Diaaeldin I. Abdallah, Barbara Maurer, Christina Wagner, Susann Schönefeldt, Katrin Spirk, Alexander Pichler, Tea Pemovska, Carmen Schweicker, Daniel Pölöske, Emina Hubanic, Dennis Jungherz, Tony Andreas Müller, Myint Myat Khine Aung, Anna Orlova, Ha Thi Thanh Pham, Kerstin Zimmel, Thomas Krausgruber, Christoph Bock, Mathias Müller, Maik Dahlhoff, Auke Boersma, Thomas Rülicke, Roman Fleck, Elvin Dominic de Araujo, Patrick Thomas Gunning, Tero Aittokallio, Satu Mustjoki, Takaomi Sanda, Sylvia Hartmann, Florian Grebien, Gregor Hoermann, Torsten Haferlach, Philipp Bernhard Staber, Heidi Anne Neubauer, Alfred Thomas Look, Marco Herling, Richard Moriggl

J Clin Invest. 2024 Apr 15; 134(8): e168536. Published online 2024 Apr 15. doi: 10.1172/JCI168536

PMCID:: PMC11014662

Abstract Article PDF–9.6M

Select item 108632915.

IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation

Jie Yang, Jiao Chen, Jingjie Chang, Xiaoyan Sun, Qingyun Wei, Xueting Cai, Peng Cao

Cell Commun Signal. 2024; 22: 116. Published online 2024 Feb 12. doi: 10.1186/s12964-023-01367-y

PMCID:: PMC10863291

Abstract Article PDF–4.9M

Select item 107689766.

A novel EGFR variant EGFRx maintains glioblastoma stem cells through STAT5

Wei Huang, Jing Li, Hongtao Zhu, Xuhui Qin, Chao Chen, Bing Wang, Jinxia Wei, Yanyang Song, Xia Lu, Zhongyu Li, Wenqing Xia, Aodi He, Lidong Cheng, Xingjiang Yu, Kai Shu, Wei Wang

Neuro Oncol. 2024 Jan; 26(1): 85–99. Published online 2023 Aug 24. doi: 10.1093/neuonc/noad153

PMCID:: PMC10768976

Abstract Article PDF–10M

Select item 102474337.

Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of Th9 cells to promote allergic inflammation

Aran Son, Francoise Meylan, Julio Gomez-Rodriguez, Zenia Kaul, McKella Sylvester, Guido H. Falduto, Estefania Vazquez, Tamara Haque, Moses M. Kitakule, Chujun Wang, Kalpana Manthiram, Chen-Feng Qi, Jun Cheng, Rama K. Gurram, Jinfang Zhu, Pamela Schwartzberg, Joshua D. Milner, Pamela A. Frischmeyer-Guerrerio, Daniella M. Schwartz

Nat Immunol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Nat Immunol. 2023 Jun; 24(6): 1036–1048. Published online 2023 Apr 27. doi: 10.1038/s41590-023-01501-5

PMCID:: PMC10247433

Abstract Article PDF–4.7M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99224689.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 989984710.

STAT5b: A master regulator of key biological pathways

Madison R. Smith, Lisa R. Forbes Satter, Alexander Vargas-Hernández

Front Immunol. 2022; 13: 1025373. Published online 2023 Jan 23. doi: 10.3389/fimmu.2022.1025373

PMCID:: PMC9899847

Abstract Article PDF–1.1M

Select item 970116411.

STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential

Meng Lin, Amy T. Ku, Jie Dong, Fei Yue, Weiyu Jiang, Ahmed Atef Ibrahim, Fanglue Peng, Chad J. Creighton, Chandandeep Nagi, Carolina Gutierrez, Jeffrey M. Rosen, Xiang H.-F. Zhang, Susan G. Hilsenbeck, Xi Chen, Yi-Chieh Nancy Du, Shixia Huang, Aiping Shi, Zhimin Fan, Yi Li

Oncogene. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Oncogene. 2022 Nov; 41(48): 5214–5222. Published online 2022 Oct 19. doi: 10.1038/s41388-022-02500-w

PMCID:: PMC9701164

Abstract Article PDF–991K

Select item 956977812.

Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases

Uijin Kim, Ha Youn Shin

Int J Mol Sci. 2022 Oct; 23(19): 11297. Published online 2022 Sep 25. doi: 10.3390/ijms231911297

PMCID:: PMC9569778

Abstract Article PDF–1.0M

Select item 943491713.

PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma

I. Garces de los Fayos Alonso, L. Zujo, I. Wiest, P. Kodajova, G. Timelthaler, S. Edtmayer, M. Zrimšek, S. Kollmann, C. Giordano, M. Kothmayer, H. A. Neubauer, S. Dey, M. Schlederer, B. S. Schmalzbauer, T. Limberger, C. Probst, O. Pusch, S. Högler, S. Tangermann, O. Merkel, A. I. Schiefer, C. Kornauth, N. Prutsch, M. Zimmerman, B. Abraham, J. Anagnostopoulos, L. Quintanilla-Martinez, S. Mathas, P. Wolf, D. Stoiber, P. B. Staber, G. Egger, W. Klapper, W. Woessmann, T. A. Look, P. Gunning, S. D. Turner, R. Moriggl, S. Lagger, L. Kenner

Mol Cancer. 2022; 21: 172. Published online 2022 Aug 31. doi: 10.1186/s12943-022-01640-7

PMCID:: PMC9434917

Abstract Article PDF–4.1M

Select item 938815714.

Early B cell factor 4 modulates FAS-mediated apoptosis and promotes cytotoxic function in human immune cells

Satoshi Kubo, Rhea Kataria, Yikun Yao, Justin Q. Gabrielski, Lixin Zheng, Tovah E. Markowitz, Waipan Chan, Jian Song, Arun K. Boddapati, Keita Saeki, Björn Häupl, Ann Y. Park, Yan H. Cheng, Jing Cui, Thomas Oellerich, Michael J. Lenardo

Proc Natl Acad Sci U S A. 2022 Aug 16; 119(33): e2208522119. Published online 2022 Aug 8. doi: 10.1073/pnas.2208522119

PMCID:: PMC9388157

Abstract Article PDF–2.2M

Select item 931703715.

miR-10 and Its Negative Correlation with Serum IL-35 Concentration and Positive Correlation with STAT5a Expression in Patients with Rheumatoid Arthritis

Agnieszka Paradowska-Gorycka, Anna Wajda, Ewa Rzeszotarska, Tomasz Kmiolek, Barbara Stypinska, Ewa Dudek, Katarzyna Romanowska-Prochnicka, Piotr Syrowka

Int J Mol Sci. 2022 Jul; 23(14): 7925. Published online 2022 Jul 18. doi: 10.3390/ijms23147925

PMCID:: PMC9317037

Abstract Article PDF–1.8M

Select item 907794516.

Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren’s syndrome

Magdalena Keindl, Richard Davies, Brith Bergum, Johan G. Brun, Daniel Hammenfors, Roland Jonsson, Valeriya Lyssenko, Silke Appel

Arthritis Res Ther. 2022; 24: 101. Published online 2022 May 7. doi: 10.1186/s13075-022-02769-y

PMCID:: PMC9077945

Abstract Article PDF–2.6M

Select item 882889517.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 857389218.

STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment

Emily A. Jesser, Nicholas J. Brady, Danielle N. Huggins, Patrice M. Witschen, Christine H. O’Connor, Kathryn L. Schwertfeger

Breast Cancer Res. 2021; 23: 104. Published online 2021 Nov 7. doi: 10.1186/s13058-021-01481-0

PMCID:: PMC8573892

Abstract Article PDF–2.3M

Select item 841860519.

Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma

Jiajun Xie, Zifeng Wang, Wenjun Fan, Youping Liu, Fang Liu, Xiangbo Wan, Meiling Liu, Xuan Wang, Deshun Zeng, Yan Wang, Bin He, Min Yan, Zijian Zhang, Mengjuan Zhang, Zhijie Hou, Chunli Wang, Zhijie Kang, Wenfeng Fang, Li Zhang, Eric W-F Lam, Xiang Guo, Jinsong Yan, Yixin Zeng, Mingyuan Chen, Quentin Liu

Signal Transduct Target Ther. 2021; 6: 333. Published online 2021 Sep 4. doi: 10.1038/s41392-021-00702-4

PMCID:: PMC8418605

Abstract Article PDF–7.5M

Select item 839040120.

Aberrantly low STAT3 and STAT5 responses are associated with poor outcome and an inflammatory gene expression signature in pediatric acute myeloid leukemia

P. Narayanan, T.-K. Man, R. B. Gerbing, R. Ries, A. M. Stevens, Y.-C. Wang, X. Long, A. S. Gamis, T. Cooper, S. Meshinchi, T. A. Alonzo, M. S. Redell

Clin Transl Oncol. 2021; 23(10): 2141–2154. Published online 2021 May 4. doi: 10.1007/s12094-021-02621-w

PMCID:: PMC8390401

Abstract Article PDF–1.0M

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