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Items: 1 to 20 of 80

1.
JMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells
Ruifeng Pei, Le Zhao, Yiren Ding, Zhan Su, Deqiang Li, Shuo Zhu, Lu Xu, Wei Zhao, Wuyuan Zhou
J Transl Med. 2023; 21: 752. Published online 2023 Oct 25. doi: 10.1186/s12967-023-04394-y
PMCID:
PMC10599021
AbstractArticlePDF–3.0M
2.
JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis
Siyuan Chen, Manni Wang, Tianqi Lu, Yu Liu, Weiqi Hong, Xuemei He, Yuan Cheng, Jian Liu, Yuquan Wei, Xiawei Wei
Oncogene. 2023; 42(37): 2737–2750. Published online 2023 Aug 11. doi: 10.1038/s41388-023-02781-9
PMCID:
PMC10491492
AbstractArticlePDF–4.9M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer
Bianca Cioni, Silvia Ratti, Annamaria Piva, Irene Tripodi, Matteo Milani, Francesca Menichetti, Tiziana Langella, Laura Botti, Loris De Cecco, Claudia Chiodoni, Daniele Lecis, Mario P. Colombo
Mol Cancer Res. 2023 Jun 1; 21(6): 614–627. Published online 2023 Mar 3. doi: 10.1158/1541-7786.MCR-22-0370
PMCID:
PMC10233359
AbstractArticlePDF–12M
5.
Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer’s disease
Julie P. Merchant, Kuixi Zhu, Marc Y. R. Henrion, Syed S. A. Zaidi, Branden Lau, Sara Moein, Melissa L. Alamprese, Richard V. Pearse, II, David A. Bennett, Nilüfer Ertekin-Taner, Tracy L. Young-Pearse, Rui Chang
Commun Biol. 2023; 6: 503. Published online 2023 May 15. doi: 10.1038/s42003-023-04791-5
PMCID:
PMC10185548
AbstractArticlePDF–7.1M
6.
Fibronectin and JMJD6 Signature in Circulating Placental Extracellular Vesicles for the Detection of Preeclampsia
Sruthi Alahari, Jonathan Ausman, Tyler Porter, Chanho Park, Ante B V Pettersson, Miira M Klemetti, Jianhong Zhang, Martin Post, Isabella Caniggia
Endocrinology. 2023 Apr; 164(4): bqad013. Published online 2023 Jan 23. doi: 10.1210/endocr/bqad013
PMCID:
PMC9939344
AbstractArticle
7.
JMJD6 orchestrates a transcriptional program in favor of endocrine resistance in ER+ breast cancer cells
Partha Das, Aritra Gupta, Kartiki V. Desai
Front Endocrinol (Lausanne) 2022; 13: 1028616. Published online 2022 Nov 7. doi: 10.3389/fendo.2022.1028616
PMCID:
PMC9678079
AbstractArticlePDF–3.6M
8.
FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ
Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li
Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831
PMCID:
PMC9491713
AbstractArticlePDF–12M
9.
An Oncogenic JMJD6-DGAT1 Axis Tunes Epigenetic Regulation of Lipid Droplet Formation in Clear Cell Renal Cell Carcinoma
Jin Zhou, Jeremy M. Simon, Chengheng Liao, Cheng Zhang, Lianxin Hu, Giada Zurlo, Xijuan Liu, Cheng Fan, Austin Hepperla, Liwei Jia, Vanina Toffessi Tcheuyap, Hua Zhong, Roy Elias, Jin Ye, W. Mike Henne, Payal Kapur, Deepak Nijhawan, James Brugarolas, Qing Zhang
Mol Cell. Author manuscript; available in PMC 2023 Aug 18.
Published in final edited form as: Mol Cell. 2022 Aug 18; 82(16): 3030–3044.e8. Published online 2022 Jun 27. doi: 10.1016/j.molcel.2022.06.003
PMCID:
PMC9391320
AbstractArticlePDF–3.0M
10.
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6
Matthew E. Cockman, Yoichiro Sugimoto, Hamish B. Pegg, Norma Masson, Eidarus Salah, Anthony Tumber, Helen R. Flynn, Joanna M. Kirkpatrick, Christopher J. Schofield, Peter J. Ratcliffe
Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32): e2201483119. Published online 2022 Aug 5. doi: 10.1073/pnas.2201483119
PMCID:
PMC9371714
AbstractArticlePDF–1.9M
11.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
14.
Role of the Epigenetic Modifier JMJD6 in Tumor Development and Regulation of Immune Response
Kai Wang, Chao Yang, Haibin Li, Xiaoyan Liu, Meiling Zheng, Zixue Xuan, Zhiqiang Mei, Haiyong Wang
Front Immunol. 2022; 13: 859893. Published online 2022 Mar 14. doi: 10.3389/fimmu.2022.859893
PMCID:
PMC8963961
AbstractArticlePDF–7.4M
15.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
16.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
17.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
18.
Computational and Mass Spectrometry-Based Approach Identify Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in JMJD6
Tianqi Gong, Lujie Yang, Fenglin Shen, Hao Chen, Ziyue Pan, Quanqing Zhang, Yan Jiang, Fan Zhong, Pengyuan Yang, Yang Zhang
Molecules. 2021 Aug; 26(15): 4653. Published online 2021 Jul 31. doi: 10.3390/molecules26154653
PMCID:
PMC8347302
AbstractArticlePDF–1.9M
19.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
20.
JMJD6 is a druggable oxygenase that regulates AR-V7 expression in prostate cancer
Alec Paschalis, Jonathan Welti, Antje J. Neeb, Wei Yuan, Ines Figueiredo, Rita Pereira, Ana Ferreira, Ruth Riisnaes, Daniel Nava Rodrigues, Juan M. Jiménez-Vacas, Soojin Kim, Takuma Uo, Patrizio Di Micco, Anthony Tumber, Saiful Islam, Marc A. Moesser, Martine Abboud, Akane Kawamura, Bora Gurel, Rossitza Christova, Veronica S. Gil, Lorenzo Buroni, Mateus Crespo, Susana Miranda, Maryou B Lambros, Suzanne Carreira, Nina Tunariu, Andrea Alimonti, SU2C/PCF International Prostate Cancer Dream Team, Bissan Al-Lazikani, Christopher J. Schofield, Stephen R. Plymate, Adam Sharp, Johann S. de Bono
Cancer Res. Author manuscript; available in PMC 2021 Aug 15.
Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 1087–1100. doi: 10.1158/0008-5472.CAN-20-1807
PMCID:
PMC8025710
AbstractArticlePDF–2.1M

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