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Select item 110607181.

Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission

Renbo Mao, Jianjun Yu, Bowen Deng, Xihuimin Dai, Yuyao Du, Sujie Du, Wenxia Zhang, Yi Rao

eLife. 2024; 12: RP91927. Published online 2024 Apr 30. doi: 10.7554/eLife.91927

PMCID:: PMC11060718

Abstract Article PDF–4.3M

Select item 107640092.

Nicotinic acetylcholine receptor signaling maintains epithelial barrier integrity

Nadja S Katheder, Kristen C Browder, Diana Chang, Ann De Maziere, Pekka Kujala, Suzanne van Dijk, Judith Klumperman, Tzu-Chiao Lu, Hongjie Li, Zijuan Lai, Dewakar Sangaraju, Heinrich Jasper

eLife. 2023; 12: e86381. Published online 2023 Dec 8. doi: 10.7554/eLife.86381

PMCID:: PMC10764009

Abstract Article PDF–13M

Select item 102550493.

Control of Synaptic Levels of Nicotinic Acetylcholine Receptor by the Sequestering Subunit Dα5 and Secreted Scaffold Protein Hig

Minoru Nakayama, Osamu Nishimura, Yuhi Nishimura, Miwa Kitaichi, Shigehiro Kuraku, Masaki Sone, Chihiro Hama

J Neurosci. 2023 May 31; 43(22): 3989–4004. doi: 10.1523/JNEUROSCI.2243-21.2023

PMCID:: PMC10255049

Abstract Article PDF–7.4M

Select item 99343674.

Functional impact of subunit composition and compensation on Drosophila melanogaster nicotinic receptors–targets of neonicotinoids

Yuma Komori, Koichi Takayama, Naoki Okamoto, Masaki Kamiya, Wataru Koizumi, Makoto Ihara, Daitaro Misawa, Kotaro Kamiya, Yuto Yoshinari, Kazuki Seike, Shu Kondo, Hiromu Tanimoto, Ryusuke Niwa, David B. Sattelle, Kazuhiko Matsuda

PLoS Genet. 2023 Feb; 19(2): e1010522. Published online 2023 Feb 16. doi: 10.1371/journal.pgen.1010522

PMCID:: PMC9934367

Abstract Article PDF–3.7M

Select item 96356445.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 92396806.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 91100307.

Drosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins

Dagmara Korona, Benedict Dirnberger, Carlo NG Giachello, Rayner ML Queiroz, Rebeka Popovic, Karin H Müller, David-Paul Minde, Michael J Deery, Glynnis Johnson, Lucy C Firth, Fergus G Earley, Steven Russell, Kathryn S Lilley

eLife. 2022; 11: e74322. Published online 2022 May 16. doi: 10.7554/eLife.74322

PMCID:: PMC9110030

Abstract Article PDF–11M

Select item 88031718.

Nicotinic acetylcholine receptor modulator insecticides act on diverse receptor subtypes with distinct subunit compositions

Wanjun Lu, Zhihan Liu, Xinyu Fan, Xinzhong Zhang, Xiaomu Qiao, Jia Huang

PLoS Genet. 2022 Jan; 18(1): e1009920. Published online 2022 Jan 19. doi: 10.1371/journal.pgen.1009920

PMCID:: PMC8803171

Abstract Article PDF–1.9M

Select item 85056789.

Constructing and Tuning Excitatory Cholinergic Synapses: The Multifaceted Functions of Nicotinic Acetylcholine Receptors in Drosophila Neural Development and Physiology

Justin S. Rosenthal, Quan Yuan

Front Cell Neurosci. 2021; 15: 720560. Published online 2021 Sep 28. doi: 10.3389/fncel.2021.720560

PMCID:: PMC8505678

Abstract Article PDF–3.1M

Select item 820202110.

Temporal regulation of nicotinic acetylcholine receptor subunits supports central cholinergic synapse development in Drosophila

Justin S. Rosenthal, Jun Yin, Jingce Lei, Anupama Sathyamurthy, Jacob Short, Caixia Long, Emma Spillman, Chengyu Sheng, Quan Yuan

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2004685118. Published online 2021 May 31. doi: 10.1073/pnas.2004685118

PMCID:: PMC8202021

Abstract Article PDF–2.4M

Select item 809693211.

The Power of Drosophila melanogaster for Modeling Neonicotinoid Effects on Pollinators and Identifying Novel Mechanisms

Kiah Tasman, Sean A. Rands, James J. L. Hodge

Front Physiol. 2021; 12: 659440. Published online 2021 Apr 21. doi: 10.3389/fphys.2021.659440

PMCID:: PMC8096932

Abstract Article PDF–317K

Select item 795845612.

Drosophila clock cells use multiple mechanisms to transmit time-of-day signals in the brain

Annika F. Barber, Shi Yi Fong, Anna Kolesnik, Michael Fetchko, Amita Sehgal

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2019826118. Published online 2021 Mar 3. doi: 10.1073/pnas.2019826118

PMCID:: PMC7958456

Abstract Article PDF–1.4M

Select item 786728313.

In Silico Studies of Lamiaceae Diterpenes with Bioinsecticide Potential against Aphis gossypii and Drosophila melanogaster

Gabriela Cristina Soares Rodrigues, Mayara dos Santos Maia, Andreza Barbosa Silva Cavalcanti, Natália Ferreira de Sousa, Marcus Tullius Scotti, Luciana Scotti

Molecules. 2021 Feb; 26(3): 766. Published online 2021 Feb 2. doi: 10.3390/molecules26030766

PMCID:: PMC7867283

Abstract Article PDF–8.8M

Select item 782035614.

Neonicotinoids disrupt memory, circadian behaviour and sleep

Kiah Tasman, Sergio Hidalgo, Bangfu Zhu, Sean A. Rands, James J. L. Hodge

Sci Rep. 2021; 11: 2061. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81548-2

PMCID:: PMC7820356

Abstract Article PDF–4.1M

Select item 759125815.

Neuronal octopamine signaling regulates mating-induced germline stem cell increase in female Drosophila melanogaster

Yuto Yoshinari, Tomotsune Ameku, Shu Kondo, Hiromu Tanimoto, Takayuki Kuraishi, Yuko Shimada-Niwa, Ryusuke Niwa

eLife. 2020; 9: e57101. Published online 2020 Oct 20. doi: 10.7554/eLife.57101

PMCID:: PMC7591258

Abstract Article PDF–1.8M

Select item 756827516.

Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in Drosophila

Felipe Martelli, Zuo Zhongyuan, Julia Wang, Ching-On Wong, Nicholas E. Karagas, Ute Roessner, Thusitha Rupasinghe, Kartik Venkatachalam, Trent Perry, Hugo J. Bellen, Philip Batterham

Proc Natl Acad Sci U S A. 2020 Oct 13; 117(41): 25840–25850. Published online 2020 Sep 28. doi: 10.1073/pnas.2011828117

PMCID:: PMC7568275

Abstract Article PDF–2.0M

Select item 749866517.

Better Sleep at Night: How Light Influences Sleep in Drosophila

Gabriella M. Mazzotta, Milena Damulewicz, Paola Cusumano

Front Physiol. 2020; 11: 997. Published online 2020 Sep 4. doi: 10.3389/fphys.2020.00997

PMCID:: PMC7498665

Abstract Article PDF–1.4M

Select item 736829418.

Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions

Makoto Ihara, Shogo Furutani, Sho Shigetou, Shota Shimada, Kunihiro Niki, Yuma Komori, Masaki Kamiya, Wataru Koizumi, Leo Magara, Mai Hikida, Akira Noguchi, Daiki Okuhara, Yuto Yoshinari, Shu Kondo, Hiromu Tanimoto, Ryusuke Niwa, David B. Sattelle, Kazuhiko Matsuda

Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16283–16291. Published online 2020 Jul 1. doi: 10.1073/pnas.2003667117