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Select item 111928391.

Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models

Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James AK Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth

Life Sci Alliance. 2024 Sep; 7(9): e202402853. Published online 2024 Jun 21. doi: 10.26508/lsa.202402853

PMCID:: PMC11192839

Abstract Article PDF–3.3M

Select item 111132682.

Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster

Analisa L. Taylor, Olga Dubuisson, Pritika Pandey, Elizabeth R. M. Zunica, Bolormaa Vandanmagsar, Wagner S. Dantas, Alyssa Johnson, Christopher L. Axelrod, John P. Kirwan

Aging Cell. 2024 May; 23(5): e14107. Published online 2024 Feb 11. doi: 10.1111/acel.14107

PMCID:: PMC11113268

Abstract Article PDF–655K

Select item 110264133.

Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila

Jenny Zhe Liao, Hyung-lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C. Marcogliese, Katherine Sew, Hugo J. Bellen, Esther M. Verheyen

Nat Commun. 2024; 15: 3326. Published online 2024 Apr 18. doi: 10.1038/s41467-024-47623-8

PMCID:: PMC11026413

Abstract Article PDF–18M

Select item 110149924.

Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model

Callum Dark, Nashia Ali, Sofya Golenkina, Vaibhav Dhyani, Ronnie Blazev, Benjamin L Parker, Kate T Murphy, Gordon S Lynch, Tarosi Senapati, S Sean Millard, Sarah M Judge, Andrew R Judge, Lopamudra Giri, Sarah M Russell, Louise Y Cheng

EMBO Rep. 2024 Apr; 25(4): 1835–1858. Published online 2024 Mar 1. doi: 10.1038/s44319-024-00102-z

PMCID:: PMC11014992

Abstract Article PDF–6.2M

Select item 110123515.

Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster

Viktor Vedelek, Ferenc Jankovics, János Zádori, Rita Sinka

Int J Mol Sci. 2024 Apr; 25(7): 3980. Published online 2024 Apr 3. doi: 10.3390/ijms25073980

PMCID:: PMC11012351

Abstract Article PDF–7.4M

Select item 110015866.

A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis

Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal

Nat Neurosci. 2024; 27(4): 666–678. Published online 2024 Feb 15. doi: 10.1038/s41593-023-01568-1

PMCID:: PMC11001586

Abstract Article PDF–5.6M

Select item 109904847.

Expanding the Drosophila toolkit for dual control of gene expression

Jonathan Zirin, Barbara Jusiak, Raphael Lopes, Benjamin Ewen-Campen, Justin A Bosch, Alexandria Risbeck, Corey Forman, Christians Villalta, Yanhui Hu, Norbert Perrimon

eLife. 2024; 12: RP94073. Published online 2024 Apr 3. doi: 10.7554/eLife.94073

PMCID:: PMC10990484

Abstract Article PDF–6.0M

Select item 108405148.

COPI-regulated mitochondria-ER contact site formation maintains axonal integrity

Daniel C. Maddison, Bilal Malik, Leonardo Amadio, Dana M. Bis-Brewer, Stephan Züchner, Owen M. Peters, Gaynor A. Smith

Cell Rep. 2023 Aug 29; 42(8): 112883. Published online 2023 Jul 26. doi: 10.1016/j.celrep.2023.112883

PMCID:: PMC10840514

Abstract Article

Select item 106655749.

Protein modification regulated autophagy in Bombyx mori and Drosophila melanogaster

Wenmei Wu, Luobin Lin, Yuntao Zhao, Huaqin Li, Rongxin Zhang

Front Physiol. 2023; 14: 1281555. Published online 2023 Nov 9. doi: 10.3389/fphys.2023.1281555

PMCID:: PMC10665574

Abstract Article PDF–1.1M

Select item 1064507910.

Structure and molecular basis of spermatid elongation in the Drosophila testis

Qiuru Huang, Xia Chen, Hao Yu, Li Ji, Yi Shi, Xinmeng Cheng, Hao Chen, Jun Yu

Open Biol. 2023 Nov; 13(11): 230136. Published online November 8, 2023. doi: 10.1098/rsob.230136

PMCID:: PMC10645079

Abstract Article PDF–1.0M

Select item 1061585711.

A Comprehensive Approach to Sample Preparation for Electron Microscopy and the Assessment of Mitochondrial Morphology in Tissue and Cultured Cells

Antentor Hinton, Jr, Prasanna Katti, Trace A. Christensen, Margaret Mungai, Jianqiang Shao, Liang Zhang, Sergey Trushin, Ahmad Alghanem, Adam Jaspersen, Rachel E. Geroux, Kit Neikirk, Michelle Biete, Edgar Garza Lopez, Bryanna Shao, Zer Vue, Larry Vang, Heather K. Beasley, Andrea G. Marshall, Dominique Stephens, Steven Damo, Jessica Ponce, Christopher K. E. Bleck, Innes Hicsasmaz, Sandra A. Murray, Ranthony A. C. Edmonds, Andres Dajles, Young Do Koo, Serif Bacevac, Jeffrey L. Salisbury, Renata O. Pereira, Brian Glancy, Eugenia Trushina, E. Dale Abel

Adv Biol (Weinh) Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Adv Biol (Weinh). 2023 Oct; 7(10): e2200202. Published online 2023 May 4. doi: 10.1002/adbi.202200202

PMCID:: PMC10615857

Abstract Article PDF–4.8M

Select item 1057242212.

PolyQ-Expansion Causes Mitochondria Fragmentation Independent of Huntingtin and Is Distinct from Traumatic Brain Injury (TBI)/Mechanical Stress-Mediated Fragmentation Which Results from Cell Death

Kelsey Swinter, Dania Salah, Rasika Rathnayake, Shermali Gunawardena

Cells. 2023 Oct; 12(19): 2406. Published online 2023 Oct 5. doi: 10.3390/cells12192406

PMCID:: PMC10572422

Abstract Article PDF–12M

Select item 1050201313.

Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster

Kristina Corthals, Vilma Andersson, Allison Churcher, Johan Reimegård, Anders Enjin

Sci Rep. 2023; 13: 15202. Published online 2023 Sep 14. doi: 10.1038/s41598-023-42506-2

PMCID:: PMC10502013

Abstract Article PDF–5.5M

Select item 1044453814.

A Novel Interaction between MFN2/Marf and MARK4/PAR-1 Is Implicated in Synaptic Defects and Mitochondrial Dysfunction

Yeongmi Cheon, Sunggyu Yoon, Jae-Hyuk Lee, Kiyoung Kim, Hyung-Jun Kim, Sung Wook Hong, Ye-Rang Yun, Jiwon Shim, Sung-Hak Kim, Bingwei Lu, Mihye Lee, Seongsoo Lee

eNeuro. 2023 Aug; 10(8): ENEURO.0409-22.2023. Prepublished online 2023 Aug 7. Published online 2023 Aug 14. doi: 10.1523/ENEURO.0409-22.2023

PMCID:: PMC10444538

Abstract Article PDF–2.9M

Select item 1036172115.

Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity

Katja Birker, Shuchao Ge, Natalie J Kirkland, Jeanne L Theis, James Marchant, Zachary C Fogarty, Maria A Missinato, Sreehari Kalvakuri, Paul Grossfeld, Adam J Engler, Karen Ocorr, Timothy J Nelson, Alexandre R Colas, Timothy M Olson, Georg Vogler, Rolf Bodmer

eLife. 2023; 12: e83385. Published online 2023 Jul 5. doi: 10.7554/eLife.83385

PMCID:: PMC10361721

Abstract Article PDF–11M

Select item 1024744816.

“Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1”

Y Nemtsova, BL Steinert, KA Wharton

Mol Cell Neurosci. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Mol Cell Neurosci. 2023 Jun; 125: 103834. Published online 2023 Mar 1. doi: 10.1016/j.mcn.2023.103834

PMCID:: PMC10247448

Abstract Article PDF–2.3M

Select item 1016254517.

Bendless is essential for PINK1-Park mediated Mitofusin degradation under mitochondrial stress caused by loss of LRPPRC

Rajit Narayanan Cheramangalam, Tarana Anand, Priyanka Pandey, Deepa Balasubramanian, Reshmi Varghese, Neha Singhal, Sonal Nagarkar Jaiswal, Manish Jaiswal

PLoS Genet. 2023 Apr; 19(4): e1010493. Published online 2023 Apr 25. doi: 10.1371/journal.pgen.1010493

PMCID:: PMC10162545

Abstract Article PDF–7.7M

Select item 1015096318.

Insights from Drosophila on Aβ- and tau-induced mitochondrial dysfunction: mechanisms and tools

Vanlalrinchhani Varte, Jeremy W. Munkelwitz, Diego E. Rincon-Limas

Front Neurosci. 2023; 17: 1184080. Published online 2023 Apr 17. doi: 10.3389/fnins.2023.1184080

PMCID:: PMC10150963

Abstract Article PDF–3.9M

Select item 1011291319.

Mitochondrial respiration and dynamics of in vivo neural stem cells

Stavroula Petridi, Dnyanesh Dubal, Richa Rikhy, Jelle van den Ameele

Development. 2022 Dec 1; 149(23): dev200870. Published online 2022 Nov 30. doi: 10.1242/dev.200870

PMCID:: PMC10112913

Abstract Article

Select item 995345120.

Mitochondrial Neurodegeneration: Lessons from Drosophila melanogaster Models

Michele Brischigliaro, Erika Fernandez-Vizarra, Carlo Viscomi

Biomolecules. 2023 Feb; 13(2): 378. Published online 2023 Feb 16. doi: 10.3390/biom13020378

PMCID:: PMC9953451

Abstract Article PDF–1.6M

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