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Items: 1 to 20 of 54

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
KV1.5–KVβ1.3 Recycling Is PKC-Dependent
Alvaro Macias, Alicia de la Cruz, Diego A. Peraza, Angela de Benito-Bueno, Teresa Gonzalez, Carmen Valenzuela
Int J Mol Sci. 2021 Feb; 22(3): 1336. Published online 2021 Jan 29. doi: 10.3390/ijms22031336
PMCID:
PMC7866247
AbstractArticlePDF–2.1M
3.
Selective expression of KCNA5 and KCNB1 genes in gastric and colorectal carcinoma
Azer Farah, Maria Kabbage, Salsabil Atafi, Amira Jaballah Gabteni, Mouadh Barbirou, Mouna Madhioub, Lamine Hamzaoui, Mousadak Azzouz Mohamed, Hassen Touinsi, Asma Ouakaa Kchaou, Emna Chelbi, Samir Boubaker, Rahma Ben Abderrazek, Balkiss Bouhaouala-Zahar
BMC Cancer. 2020; 20: 1179. Published online 2020 Dec 2. doi: 10.1186/s12885-020-07647-x
PMCID:
PMC7709444
AbstractArticlePDF–1.3M
4.
Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies
Jérôme Clatot, Nathalie Neyroud, Robert Cox, Charlotte Souil, Jing Huang, Pascale Guicheney, Charles Antzelevitch
Int J Mol Sci. 2020 Jul; 21(14): 5057. Published online 2020 Jul 17. doi: 10.3390/ijms21145057
PMCID:
PMC7404392
AbstractArticlePDF–2.2M
5.
Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels
Shanshan Song, Aleksandra Babicheva, Tengteng Zhao, Ramon J. Ayon, Marisela Rodriguez, Shamin Rahimi, Francesca Balistrieri, Angela Harrington, John Y.-J. Shyy, Patricia A. Thistlethwaite, Ayako Makino, Jason X.-J. Yuan
Am J Physiol Cell Physiol. 2020 May 1; 318(5): C954–C968. Published online 2020 Mar 18. doi: 10.1152/ajpcell.00487.2019
PMCID:
PMC7294324
AbstractArticle
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
Mechanical stretch increases Kv1.5 current through an interaction between the S1–S2 linker and N-terminus of the channel
Alexandria O. Milton, Tingzhong Wang, Wentao Li, Jun Guo, Shetuan Zhang
J Biol Chem. 2020 Apr 3; 295(14): 4723–4732. Published online 2020 Mar 2. doi: 10.1074/jbc.RA119.011302
PMCID:
PMC7136002
AbstractArticlePDF–2.6M
8.
Challenges Faced with Small Molecular Modulators of Potassium Current Channel Isoform Kv1.5
Zefeng Zhao, Songsong Ruan, Xiaoming Ma, Qian Feng, Zhuosong Xie, Zhuang Nie, Peinan Fan, Mingcheng Qian, Xirui He, Shaoping Wu, Yongmin Zhang, Xiaohui Zheng
Biomolecules. 2020 Jan; 10(1): 10. Published online 2019 Dec 19. doi: 10.3390/biom10010010
PMCID:
PMC7022446
AbstractArticlePDF–18M
9.
Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy
Changlong Liu, Carolyn E. Banister, Phillip J. Buckhaults
Cancer Res. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Cancer Res. 2019 May 1; 79(9): 2392–2403. Published online 2019 Mar 12. doi: 10.1158/0008-5472.CAN-18-3024
PMCID:
PMC6497569
AbstractArticlePDF–2.2M
10.
The N terminus and transmembrane segment S1 of Kv1.5 can coassemble with the rest of the channel independently of the S1–S2 linkage
Shawn M. Lamothe, Aja E. Hogan-Cann, Wentao Li, Jun Guo, Tonghua Yang, Jared N. Tschirhart, Shetuan Zhang
J Biol Chem. 2018 Oct 5; 293(40): 15347–15358. Published online 2018 Aug 17. doi: 10.1074/jbc.RA118.004065
PMCID:
PMC6177590
AbstractArticlePDF–2.7M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis
Michael A. Colman, Haibo Ni, Bo Liang, Nicole Schmitt, Henggui Zhang
PLoS Comput Biol. 2017 Jun; 13(6): e1005587. Published online 2017 Jun 16. doi: 10.1371/journal.pcbi.1005587
PMCID:
PMC5493429
AbstractArticlePDF–13M
13.
Putative binding sites for arachidonic acid on the human cardiac Kv1.5 channel
Jia‐Yu Bai, Wei‐Guang Ding, Akiko Kojima, Tomoyoshi Seto, Hiroshi Matsuura
Br J Pharmacol. 2015 Nov; 172(22): 5281–5292. Published online 2015 Oct 22. doi: 10.1111/bph.13314
PMCID:
PMC5341216
AbstractArticlePDF–2.1M
14.
Caveolin interaction governs Kv1.3 lipid raft targeting
Mireia Pérez-Verdaguer, Jesusa Capera, Ramón Martínez-Mármol, Marta Camps, Núria Comes, Michael M. Tamkun, Antonio Felipe
Sci Rep. 2016; 6: 22453. Published online 2016 Mar 2. doi: 10.1038/srep22453
PMCID:
PMC4773814
AbstractArticlePDF–1.5M
15.
Promoter Methylation Analysis Reveals that KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation
Katherine E Ryland, Allegra G. Hawkins, Daniel J. Weisenberger, Vasu Punj, Scott C. Borinstein, Peter W. Laird, Jeffrey R. Martens, Elizabeth R. Lawlor
Mol Cancer Res. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Mol Cancer Res. 2016 Jan; 14(1): 26–34. Published online 2015 Nov 16. doi: 10.1158/1541-7786.MCR-15-0343
PMCID:
PMC4716008
AbstractArticlePDF–1.3M
16.
Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells
Jin Wu, Zhida Chen, Qingjun Liu, Wenrong Zeng, Xinyu Wu, Bin Lin
Int J Mol Sci. 2015 Nov; 16(11): 26914–26926. Published online 2015 Nov 11. doi: 10.3390/ijms161126002
PMCID:
PMC4661860
AbstractArticlePDF–6.2M
17.
Polycomb-Dependent Repression of the Potassium Channel-Encoding Gene KCNA5 Promotes Cancer Cell Survival Under Conditions of Stress
Katherine E Ryland, Laurie K. Svoboda, Eileen D Vesely, Jeremy C. McIntyre, Lian Zhang, Jeffrey R. Martens, Elizabeth R. Lawlor
Oncogene. Author manuscript; available in PMC 2016 Feb 27.
Published in final edited form as: Oncogene. 2015 Aug 27; 34(35): 4591–4600. Published online 2014 Dec 1. doi: 10.1038/onc.2014.384
PMCID:
PMC4451446
AbstractArticlePDF–2.5M
18.
Remodeling of Kv1.5 Channel in Right Atria from Han Chinese Patients with Atrial Fibrillation
Xian-hong Ou, Miao-ling Li, Rui Liu, Xin-rong Fan, Liang Mao, Xue-hui Fan, Yan Yang, Xiao-rong Zeng
Med Sci Monit. 2015; 21: 1207–1213. Published online 2015 Apr 28. doi: 10.12659/MSM.893533
PMCID:
PMC4424910
AbstractArticlePDF–368K
19.
PKC inhibition results in a Kv1.5 + Kvβ1.3 pharmacology closer to Kv1.5 channels
A Macías, A de la Cruz, A Prieto, D A Peraza, M M Tamkun, T González, C Valenzuela
Br J Pharmacol. 2014 Nov; 171(21): 4914–4926. Published online 2014 Sep 5. doi: 10.1111/bph.12822
PMCID:
PMC4294114
AbstractArticlePDF–1.6M
20.
Novel Mutations in BMPR2, ACVRL1 and KCNA5 Genes and Hemodynamic Parameters in Patients with Pulmonary Arterial Hypertension
Guillermo Pousada, Adolfo Baloira, Carlos Vilariño, Jose Manuel Cifrian, Diana Valverde
PLoS One. 2014; 9(6): e100261. Published online 2014 Jun 17. doi: 10.1371/journal.pone.0100261
PMCID:
PMC4061078
AbstractArticlePDF–258K

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