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Items: 1 to 20 of 106

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1
Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt
Cells. 2023 Jan; 12(1): 201. Published online 2023 Jan 3. doi: 10.3390/cells12010201
PMCID:
PMC9818768
AbstractArticlePDF–7.7M
3.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Role of CASP7 polymorphisms in noise-induced hearing loss risk in Han Chinese population
Yanmei Ruan, Jinwei Zhang, Shiqi Mai, Wenfeng Zeng, Lili Huang, Chunrong Gu, Keping Liu, Yuying Ma, Zhi Wang
Sci Rep. 2021; 11: 1803. Published online 2021 Jan 19. doi: 10.1038/s41598-021-81391-5
PMCID:
PMC7815823
AbstractArticlePDF–2.3M
6.
Engineering Caspase 7 as an Affinity Reagent to Capture Proteolytic Products
Amir S Razai, Scott J Snipas, Marcin Poreba, Domenico Fasci, Guy S Salvesen
FEBS J. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: FEBS J. 2021 Feb; 288(4): 1259–1270. Published online 2020 Jul 11. doi: 10.1111/febs.15467
PMCID:
PMC7779697
AbstractArticlePDF–1.5M
7.
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Redox Biol. 2020 Oct; 37: 101686. Published online 2020 Aug 20. doi: 10.1016/j.redox.2020.101686
PMCID:
PMC7490560
AbstractArticlePDF–8.6M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Autoimmune inner ear disease patient–associated 28-kDa proinflammatory IL-1β fragment results from caspase-7–mediated cleavage in vitro
Shresh Pathak, Andrea Vambutas
JCI Insight. 2020 Feb 13; 5(3): e130845. Published online 2020 Feb 13. doi: 10.1172/jci.insight.130845
PMCID:
PMC7098783
AbstractArticlePDF–2.0M
10.
Association of genetic polymorphisms in CASP7 with risk of ischaemic stroke
Zhaoshi Zheng, Songyan Liu, Chuheng Wang, Chunhui Wang, Dong Tang, Yuqing Shi, Xuemei Han
Sci Rep. 2019; 9: 18627. Published online 2019 Dec 9. doi: 10.1038/s41598-019-55201-y
PMCID:
PMC6901581
AbstractArticlePDF–1.7M
11.
Caspase-7 uses RNA to enhance proteolysis of poly(ADP-ribose) polymerase 1 and other RNA-binding proteins
Alexandre Desroches, Jean-Bernard Denault
Proc Natl Acad Sci U S A. 2019 Oct 22; 116(43): 21521–21528. Published online 2019 Oct 4. doi: 10.1073/pnas.1909283116
PMCID:
PMC6815152
AbstractArticlePDF–1.5M
12.
Targeting SREBP1 chemosensitizes colorectal cancer cells to gemcitabine by caspase-7 upregulation
Wenlong Shen, Ting Xu, Dong Chen, Xiaojie Tan
Bioengineered. 2019; 10(1): 459–468. Published online 2019 Oct 10. doi: 10.1080/21655979.2019.1676485
PMCID:
PMC6802928
AbstractArticlePDF–2.2M
13.
Maximizing binary interactome mapping with a minimal number of assays
Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre-Olivier Vidalain, Katja Luck, Luke Lambourne, Kerstin Spirohn, Irma Lemmens, Mélanie Dos Santos, Caroline Demeret, Louis Jones, Sudharshan Rangarajan, Wenting Bian, Eloi P. Coutant, Yves L. Janin, Sylvie van der Werf, Philipp Trepte, Erich E. Wanker, Javier De Las Rivas, Jan Tavernier, Jean-Claude Twizere, Tong Hao, David E. Hill, Marc Vidal, Michael A. Calderwood, Yves Jacob
Nat Commun. 2019; 10: 3907. Published online 2019 Aug 29. doi: 10.1038/s41467-019-11809-2
PMCID:
PMC6715725
AbstractArticlePDF–1.7M
14.
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7
Scott McComb, Pik Ki Chan, Anna Guinot, Holmfridur Hartmannsdottir, Silvia Jenni, Maria Pamela Dobay, Jean-Pierre Bourquin, Beat C. Bornhauser
Sci Adv. 2019 Jul; 5(7): eaau9433. Published online 2019 Jul 31. doi: 10.1126/sciadv.aau9433
PMCID:
PMC6669006
AbstractArticlePDF–3.5M
15.
Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation
Shih-Han Lee, Christine Mayr
Mol Cell. Author manuscript; available in PMC 2020 May 16.
Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006
PMCID:
PMC6581197
AbstractArticlePDF–2.0M
16.
Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages
Saikat Boliar, David W. Gludish, Kondwani C. Jambo, Raphael Kamng’ona, Leonard Mvaya, Henry C. Mwandumba, David G. Russell
Proc Natl Acad Sci U S A. 2019 Apr 9; 116(15): 7431–7438. Published online 2019 Mar 27. doi: 10.1073/pnas.1818662116
PMCID:
PMC6462110
AbstractArticlePDF–1.4M
17.
A rare missense variant in CASP7 is associated with familial late-onset Alzheimer disease
Xiaoling Zhang, Congcong Zhu, Gary Beecham, Badri N. Vardarajan, Yiyi Ma, Daniel Lancour, John J. Farrell, Jaeyoon Chung, Alzheimer’s Disease Sequencing Project , Richard Mayeux, Jonathan L. Haines, Gerard D. Schellenberg, Margaret A. Pericak-Vance, Kathryn L Lunetta, Lindsay A. Farrer
Alzheimers Dement. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Alzheimers Dement. 2019 Mar; 15(3): 441–452. Published online 2019 Jan 3. doi: 10.1016/j.jalz.2018.10.005
PMCID:
PMC6408965
AbstractArticlePDF–564K
18.
Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis
Gyu-Tae Shin, Hwa Joung Lee, Ji Eun Park
PLoS One. 2019; 14(2): e0212818. Published online 2019 Feb 22. doi: 10.1371/journal.pone.0212818
PMCID:
PMC6386268
AbstractArticlePDF–3.4M
19.
Physiological and pathophysiological characteristics of ataxin-3 isoforms
Daniel Weishäupl, Juliane Schneider, Barbara Peixoto Pinheiro, Corinna Ruess, Sandra Maria Dold, Felix von Zweydorf, Christian Johannes Gloeckner, Jana Schmidt, Olaf Riess, Thorsten Schmidt
J Biol Chem. 2019 Jan 11; 294(2): 644–661. Published online 2018 Nov 19. doi: 10.1074/jbc.RA118.005801
PMCID:
PMC6333899
AbstractArticlePDF–3.0M
20.
Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
Pedro H. V. Saavedra, Linyan Huang, Farzaneh Ghazavi, Stephanie Kourula, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeele, Mohamed Lamkanfi
Nat Commun. 2018; 9: 4846. Published online 2018 Nov 19. doi: 10.1038/s41467-018-07386-5
PMCID:
PMC6242954
AbstractArticlePDF–1.5M

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