PMC Links for GEO Profiles (Select 33674695) - PMC

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103089505.

Hepatitis E Virus Protease Inhibits the Activity of Eukaryotic Initiation Factor 2-Alpha Kinase 4 and Promotes Virus Survival

Amit Kumar, Chandru Subramani, Shivani Raj, C. T. Ranjith-Kumar, Milan Surjit

J Virol. 2023 Jun; 97(6): e00347-23. Published online 2023 May 18. doi: 10.1128/jvi.00347-23

PMCID:: PMC10308950

Abstract Article PDF–2.3M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101276937.

Contributions of Ccr4 and Gcn2 to the Translational Response of C. neoformans to Host-Relevant Stressors and Integrated Stress Response Induction

Corey M. Knowles, David Goich, Amanda L. M. Bloom, Murat C. Kalem, John C. Panepinto

mBio. 2023 Mar-Apr; 14(2): e00196-23. Published online 2023 Apr 5. doi: 10.1128/mbio.00196-23

PMCID:: PMC10127693

Abstract Article PDF–3.8M

Select item 100729068.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100020139.

Multiple Roles of the Stress Sensor GCN2 in Immune Cells

Chenxu Zhao, Han Guo, Yangxiao Hou, Tong Lei, Dong Wei, Yong Zhao

Int J Mol Sci. 2023 Mar; 24(5): 4285. Published online 2023 Feb 21. doi: 10.3390/ijms24054285

PMCID:: PMC10002013

Abstract Article PDF–2.3M

Select item 999446210.

An E3 ligase network engages GCN1 to promote degradation of translation factors on stalled ribosomes

Keely Oltion, Jordan D. Carelli, Tangpo Yang, Stephanie K. See, Hao-Yuan Wang, Martin Kampmann, Jack Taunton

Cell. Author manuscript; available in PMC 2024 Jan 19.

Published in final edited form as: Cell. 2023 Jan 19; 186(2): 346–362.e17. Published online 2023 Jan 12. doi: 10.1016/j.cell.2022.12.025

PMCID:: PMC9994462

Abstract Article PDF–2.4M

Select item 992246811.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 977534912.

Lipidomic Profile Analysis of Lung Tissues Revealed Lipointoxication in Pulmonary Veno-Occlusive Disease

Spiro Khoury, Antoine Beauvais, Jenny Colas, Anaïs Saint-Martin Willer, Frédéric Perros, Marc Humbert, Clarisse Vandebrouck, David Montani, Thierry Ferreira, Fabrice Antigny

Biomolecules. 2022 Dec; 12(12): 1878. Published online 2022 Dec 14. doi: 10.3390/biom12121878

PMCID:: PMC9775349

Abstract Article PDF–1.9M

Select item 977255813.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 976969814.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 966873215.

A cell-based chemical-genetic screen for amino acid stress response inhibitors reveals torins reverse stress kinase GCN2 signaling

Johanna B. Brüggenthies, Alessandra Fiore, Marion Russier, Christina Bitsina, Julian Brötzmann, Susanne Kordes, Sascha Menninger, Alexander Wolf, Elena Conti, Jan E. Eickhoff, Peter J. Murray

J Biol Chem. 2022 Dec; 298(12): 102629. Published online 2022 Oct 20. doi: 10.1016/j.jbc.2022.102629

PMCID:: PMC9668732

Abstract Article PDF–2.3M

Select item 957871416.

GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

Ricardo A Cordova, Jagannath Misra, Parth H Amin, Anglea J Klunk, Nur P Damayanti, Kenneth R Carlson, Andrew J Elmendorf, Hyeong-Geug Kim, Emily T Mirek, Bennet D Elzey, Marcus J Miller, X Charlie Dong, Liang Cheng, Tracy G Anthony, Roberto Pili, Ronald C Wek, Kirk A Staschke

eLife. 2022; 11: e81083. Published online 2022 Sep 15. doi: 10.7554/eLife.81083

PMCID:: PMC9578714

Abstract Article PDF–16M

Select item 948193317.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 924986818.

Amino acid sensor GCN2 promotes SARS-CoV-2 receptor ACE2 expression in response to amino acid deprivation

Xiaoming Hu, Yuguo Niu, Peixiang Luo, Fei Xiao, Feixiang Yuan, Hanrui Yin, Shanghai Chen, Feifan Guo

Commun Biol. 2022; 5: 651. Published online 2022 Jul 1. doi: 10.1038/s42003-022-03609-0

PMCID:: PMC9249868

Abstract Article PDF–1.9M

Select item 855453319.

The eIF2 kinase GCN2 directs keratinocyte collective cell migration during wound healing via coordination of reactive oxygen species and amino acids

Rebecca R. Miles, Parth H. Amin, Miguel Barriera Diaz, Jagannath Misra, Erica Aukerman, Amitava Das, Nandini Ghosh, Tanner Guith, Michael D. Knierman, Sashwati Roy, Dan F Spandau, Ronald C. Wek

J Biol Chem. 2021 Nov; 297(5): 101257. Published online 2021 Sep 29. doi: 10.1016/j.jbc.2021.101257