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Items: 1 to 20 of 36

1.
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang
Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558
PMCID:
PMC10240998
AbstractArticlePDF–4.4M
2.
The endo-lysosomal regulatory protein BLOC1S1 modulates hepatic lysosomal content and lysosomal lipolysis
Kaiyuan Wu, Jizhong Zou, Michael N. Sack
Biochem Biophys Res Commun. Author manuscript; available in PMC 2024 Jan 29.
Published in final edited form as: Biochem Biophys Res Commun. 2023 Jan 29; 642: 1–10. Published online 2022 Dec 14. doi: 10.1016/j.bbrc.2022.12.038
PMCID:
PMC9852072
AbstractArticlePDF–2.2M
3.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
4.
Mitochondrial GCN5L1 regulates glutaminase acetylation and hepatocellular carcinoma
Taotao Zhang, Yunlong Cui, Yanjin Wu, Jiahui Meng, Linmeng Han, Jiaqi Zhang, Chunyu Zhang, Chenxi Yang, Lu Chen, Xue Bai, Kai Zhang, Kaiyuan Wu, Michael N. Sack, Lingdi Wang, Lu Zhu
Clin Transl Med. 2022 May; 12(5): e852. Published online 2022 May 11. doi: 10.1002/ctm2.852
PMCID:
PMC9091986
AbstractArticlePDF–2.9M
5.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
6.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers
Shanna L. Bowman, Linh Le, Yueyao Zhu, Dawn C. Harper, Anand Sitaram, Alexander C. Theos, Elena V. Sviderskaya, Dorothy C. Bennett, Graça Raposo-Benedetti, David J. Owen, Megan K. Dennis, Michael S. Marks
J Cell Biol. 2021 Jul 5; 220(7): e202005173. Published online 2021 Apr 22. doi: 10.1083/jcb.202005173
PMCID:
PMC8077166
AbstractArticlePDF–8.4M
9.
General Control of Amino Acid Synthesis 5-Like 1-Mediated Acetylation of Manganese Superoxide Dismutase Regulates Oxidative Stress in Diabetic Kidney Disease
Tingting Lv, Yao Lu, Yi Liu, Hong Feng, Chensheng Li, Wei Sheng, Zhengguo Cui, Suwei Zhu, Xia Gu, Zhe Yang, Qiang Wan
Oxid Med Cell Longev. 2021; 2021: 6691226. Published online 2021 Feb 17. doi: 10.1155/2021/6691226
PMCID:
PMC7906818
AbstractArticlePDF–5.3M
10.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
11.
Identification of a molecular component of the mitochondrial acetyl transferase program; a novel role for GCN5L1
Iain Scott, Bradley R. Webster, Jian H. Li, Michael N. Sack
Biochem J. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Biochem J. 2012 May 1; 443(3): 655–661. doi: 10.1042/BJ20120118
PMCID:
PMC7461726
AbstractArticlePDF–1.7M
12.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
13.
Biogenesis of lysosome‐related organelles complex‐1 (BORC) regulates late endosomal/lysosomal size through PIKfyve‐dependent phosphatidylinositol‐3,5‐bisphosphate
Teodor E. Yordanov, Victoria E. B. Hipolito, Gudrun Liebscher, Georg F. Vogel, Taras Stasyk, Caroline Herrmann, Stephan Geley, David Teis, Roberto J. Botelho, Michael W. Hess, Lukas A. Huber
Traffic. 2019 Sep; 20(9): 674–696. Published online 2019 Aug 19. doi: 10.1111/tra.12679
PMCID:
PMC6771566
AbstractArticlePDF–33M
14.
CARDIAC-SPECIFIC DELETION OF GCN5L1 RESTRICTS RECOVERY FROM ISCHEMIA-REPERFUSION INJURY
Janet R Manning, Dharendra Thapa, Manling Zhang, Michael W Stoner, Javier Traba, Charles F. McTiernan, Catherine Corey, Sruti Shiva, Michael N Sack, Iain Scott
J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2019 Apr; 129: 69–78. Published online 2019 Feb 15. doi: 10.1016/j.yjmcc.2019.02.009
PMCID:
PMC6486843
AbstractArticlePDF–1.0M
15.
GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking
Kaiyuan Wu, Lingdi Wang, Yong Chen, Mehdi Pirooznia, Komudi Singh, Sarah Wälde, Ralph H. Kehlenbach, Iain Scott, Marjan Gucek, Michael N. Sack
J Cell Sci. 2018 Nov 15; 131(22): jcs221036. Published online 2018 Nov 20. doi: 10.1242/jcs.221036
PMCID:
PMC6262773
AbstractArticle
16.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
17.
A dynamic protein interaction landscape of the human centrosome-cilium interface
Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier
Cell. Author manuscript; available in PMC 2016 Dec 3.
Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065
PMCID:
PMC5089374
AbstractArticlePDF–1.5M
18.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
19.
BORC, a Multisubunit Complex that Regulates Lysosome Positioning
Jing Pu, Christina Schindler, Rui Jia, Michal Jarnik, Peter Backlund, Juan S. Bonifacino
Dev Cell. Author manuscript; available in PMC 2016 Apr 20.
Published in final edited form as: Dev Cell. 2015 Apr 20; 33(2): 176–188. doi: 10.1016/j.devcel.2015.02.011
PMCID:
PMC4788105
AbstractArticlePDF–3.2M
20.
Secretory protein trafficking and organelle dynamics in living cells.
J Lippincott-Schwartz, T H Roberts, K Hirschberg
Annu Rev Cell Dev Biol. 2000; 16: 557–589. doi: 10.1146/annurev.cellbio.16.1.557
PMCID:
PMC4781643
AbstractArticle

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