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Select item 112771511.

The Activin Branch Ligand Daw Regulates the Drosophila melanogaster Immune Response and Lipid Metabolism against the Heterorhabditis bacteriophora Serine Carboxypeptidase

Sreeradha Mallick, Eric Kenney, Ioannis Eleftherianos

Int J Mol Sci. 2024 Jul; 25(14): 7970. Published online 2024 Jul 21. doi: 10.3390/ijms25147970

PMCID:: PMC11277151

Abstract Article PDF–1.3M

Select item 112039632.

Dietary Curcumin Intake and Its Effects on the Transcriptome and Metabolome of Drosophila melanogaster

Samantha Belcher, Gerardo Flores-Iga, Purushothaman Natarajan, Garrett Crummett, Alicia Talavera-Caro, Celeste Gracia-Rodriguez, Carlos Lopez-Ortiz, Amartya Das, Donald A. Adjeroh, Padma Nimmakayala, Nagamani Balagurusamy, Umesh K. Reddy

Int J Mol Sci. 2024 Jun; 25(12): 6559. Published online 2024 Jun 14. doi: 10.3390/ijms25126559

PMCID:: PMC11203963

Abstract Article PDF–3.2M

Select item 110015823.

PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons

Carmelo Milioto, Mireia Carcolé, Ashling Giblin, Rachel Coneys, Olivia Attrebi, Mhoriam Ahmed, Samuel S. Harris, Byung Il Lee, Mengke Yang, Robert A. Ellingford, Raja S. Nirujogi, Daniel Biggs, Sally Salomonsson, Matteo Zanovello, Paula de Oliveira, Eszter Katona, Idoia Glaria, Alla Mikheenko, Bethany Geary, Evan Udine, Deniz Vaizoglu, Sharifah Anoar, Khrisha Jotangiya, Gerard Crowley, Demelza M. Smeeth, Mirjam L. Adams, Teresa Niccoli, Rosa Rademakers, Marka van Blitterswijk, Anny Devoy, Soyon Hong, Linda Partridge, Alyssa N. Coyne, Pietro Fratta, Dario R. Alessi, Ben Davies, Marc Aurel Busche, Linda Greensmith, Elizabeth M. C. Fisher, Adrian M. Isaacs

Nat Neurosci. 2024; 27(4): 643–655. Published online 2024 Feb 29. doi: 10.1038/s41593-024-01589-4

PMCID:: PMC11001582

Abstract Article PDF–12M

Select item 109627594.

A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

Annabel Guichard, Shenzhao Lu, Oguz Kanca, Daniel Bressan, Yan Huang, Mengqi Ma, Sara Sanz Juste, Jonathan C. Andrews, Kristy L. Jay, Marketta Sneider, Ruth Schwartz, Mei-Chu Huang, Danqing Bei, Hongling Pan, Liwen Ma, Wen-Wen Lin, Ankush Auradkar, Pranjali Bhagwat, Soo Park, Kenneth H. Wan, Takashi Ohsako, Toshiyuki Takano-Shimizu, Susan E. Celniker, Michael F. Wangler, Shinya Yamamoto, Hugo J. Bellen, Ethan Bier

Cell Rep. Author manuscript; available in PMC 2024 Mar 25.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112842. Published online 2023 Jul 20. doi: 10.1016/j.celrep.2023.112842

PMCID:: PMC10962759

Abstract Article PDF–3.0M

Select item 109455085.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 108477256.

Bone morphogenetic protein signaling: the pathway and its regulation

Takuya Akiyama, Laurel A Raftery, Kristi A Wharton

Genetics. 2024 Feb; 226(2): iyad200. Published online 2023 Dec 20. doi: 10.1093/genetics/iyad200

PMCID:: PMC10847725

Abstract Article PDF–6.8M

Select item 107671067.

Drosophila activins adapt gut size to food intake and promote regenerative growth

Christian F. Christensen, Quentin Laurichesse, Rihab Loudhaief, Julien Colombani, Ditte S. Andersen

Nat Commun. 2024; 15: 273. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44553-9

PMCID:: PMC10767106

Abstract Article PDF–3.4M

Select item 106904718.

Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection

Gabriela Krejčová, Cecilia Morgantini, Helena Zemanová, Volker M Lauschke, Julie Kovářová, Jiří Kubásek, Pavla Nedbalová, Nick Kamps‐Hughes, Martin Moos, Myriam Aouadi, Tomáš Doležal, Adam Bajgar

EMBO J. 2023 Dec; 42(23): e114086. Published online 2023 Oct 9. doi: 10.15252/embj.2023114086

PMCID:: PMC10690471

Abstract Article PDF–5.5M

Select item 106170089.

Regulating metabolism to shape immune function: Lessons from Drosophila

Michelle L. Bland

Semin Cell Dev Biol. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Semin Cell Dev Biol. 2023 Mar 30; 138: 128–141. Published online 2022 Apr 16. doi: 10.1016/j.semcdb.2022.04.002

PMCID:: PMC10617008

Abstract Article PDF–954K

Select item 1055657710.

Functional role of the TGF-β signaling in the Drosophila immune response

Ashley Bastin, Ioannis Eleftherianos

Curr Res Immunol. 2023; 4: 100071. Published online 2023 Sep 28. doi: 10.1016/j.crimmu.2023.100071

PMCID:: PMC10556577

Abstract Article PDF–3.2M

Select item 1011581511.

Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs

Seong Kyu Han, Michelle T. McNulty, Christopher J. Benway, Pei Wen, Anya Greenberg, Ana C. Onuchic-Whitford, Nephrotic Syndrome Study Network (NEPTUNE), Dongkeun Jang, Jason Flannick, Noël P. Burtt, Parker C. Wilson, Benjamin D. Humphreys, Xiaoquan Wen, Zhe Han, Dongwon Lee, Matthew G. Sampson

Nat Commun. 2023; 14: 2229. Published online 2023 Apr 19. doi: 10.1038/s41467-023-37691-7

PMCID:: PMC10115815

Abstract Article PDF–4.2M

Select item 1009013712.

Adult expression of Semaphorins and Plexins is essential for motor neuron survival

Aarya Vaikakkara Chithran, Douglas W. Allan, Timothy P. O’Connor

Sci Rep. 2023; 13: 5894. Published online 2023 Apr 11. doi: 10.1038/s41598-023-32943-4

PMCID:: PMC10090137

Abstract Article PDF–5.0M

Select item 995801213.

Asymmetric activity of NetrinB controls laterality of the Drosophila brain

F. Lapraz, C. Boutres, C. Fixary-Schuster, B. R. De Queiroz, P. Y. Plaçais, D. Cerezo, F. Besse, T. Préat, S. Noselli

Nat Commun. 2023; 14: 1052. Published online 2023 Feb 24. doi: 10.1038/s41467-023-36644-4

PMCID:: PMC9958012

Abstract Article PDF–2.5M

Select item 973580914.

Drosophila as an Animal Model for Testing Plant-Based Immunomodulators

Andre Rizky Pratomo, Emil Salim, Aki Hori, Takayuki Kuraishi

Int J Mol Sci. 2022 Dec; 23(23): 14801. Published online 2022 Nov 26. doi: 10.3390/ijms232314801

PMCID:: PMC9735809

Abstract Article PDF–619K

Select item 967996515.

Glial TGFβ activity promotes neuron survival in peripheral nerves

Alexandria P. Lassetter, Megan M. Corty, Romina Barria, Amy E. Sheehan, Jo Q. Hill, Sue A. Aicher, A. Nicole Fox, Marc R. Freeman

J Cell Biol. 2023 Jan 2; 222(1): e202111053. Published online 2022 Nov 18. doi: 10.1083/jcb.202111053

PMCID:: PMC9679965

Abstract Article PDF–7.6M

Select item 966833416.

Genetic architecture of natural variation of cardiac performance from flies to humans

Saswati Saha, Lionel Spinelli, Jaime A Castro Mondragon, Anaïs Kervadec, Michaela Lynott, Laurent Kremmer, Laurence Roder, Sallouha Krifa, Magali Torres, Christine Brun, Georg Vogler, Rolf Bodmer, Alexandre R Colas, Karen Ocorr, Laurent Perrin

eLife. 2022; 11: e82459. Published online 2022 Nov 16. doi: 10.7554/eLife.82459

PMCID:: PMC9668334

Abstract Article PDF–4.8M

Select item 955825717.

Diet-regulated production of PDGFcc by macrophages controls energy storage

Nehemiah Cox, Lucile Crozet, Inge R. Holtman, Pierre-Louis Loyher, Tomi Lazarov, Jessica B. White, Elvira Mass, E. Richard Stanley, Olivier Elemento, Christopher K. Glass, Frederic Geissmann

Science. Author manuscript; available in PMC 2022 Oct 13.

Published in final edited form as: Science. 2021 Jul 2; 373(6550): eabe9383. doi: 10.1126/science.abe9383

PMCID:: PMC9558257

Abstract Article PDF–3.2M

Select item 939272018.

Excreted secreted products from the parasitic nematode Steinernema carpocapsae manipulate the Drosophila melanogaster immune response

Kirah Jones, Ghada Tafesh-Edwards, Eric Kenney, Duarte Toubarro, Nelson Simões, Ioannis Eleftherianos

Sci Rep. 2022; 12: 14237. Published online 2022 Aug 20. doi: 10.1038/s41598-022-18722-7

PMCID:: PMC9392720

Abstract Article PDF–1.8M

Select item 920864819.

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-β pathway in Drosophila

Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu

Genetics. 2022 Mar; 220(3): iyab234. Published online 2021 Dec 21. doi: 10.1093/genetics/iyab234

PMCID:: PMC9208648

Abstract Article PDF–1.5M

Select item 881691920.

The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

Olga Kubrak, Takashi Koyama, Nadja Ahrentløv, Line Jensen, Alina Malita, Muhammad T. Naseem, Mette Lassen, Stanislav Nagy, Michael J. Texada, Kenneth V. Halberg, Kim Rewitz

Nat Commun. 2022; 13: 692. Published online 2022 Feb 4. doi: 10.1038/s41467-022-28268-x

PMCID:: PMC8816919

Abstract Article PDF–3.7M

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