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Items: 1 to 20 of 374

1.
Pycard deficiency inhibits microRNA maturation and prevents neointima formation by promoting chaperone-mediated autophagic degradation of AGO2/argonaute 2 in adipose tissue
Jian Li, Hongmin Yao, Fujie Zhao, Junqing An, Qilong Wang, Jing Mu, Zhixue Liu, Ming-Hui Zou, Zhonglin Xie
Autophagy. 2024; 20(3): 629–644. Published online 2023 Nov 14. doi: 10.1080/15548627.2023.2277610
PMCID:
PMC10936599
AbstractArticlePDF–5.3M
2.
Distinct roles for type I and type III interferons in virulent human metapneumovirus pathogenesis
Yu Zhang, Jiuyang Xu, Margot Miranda-Katz, Jorna Sojati, Sharon J. Tollefson, Michelle L. Manni, John F. Alcorn, Saumendra N. Sarkar, John V. Williams
PLoS Pathog. 2024 Feb; 20(2): e1011840. Published online 2024 Feb 5. doi: 10.1371/journal.ppat.1011840
PMCID:
PMC10868789
AbstractArticlePDF–2.8M
3.
Therapeutic Effects of IL-1RA against Acute Bacterial Infections, including Antibiotic-Resistant Strains
Ines Ambite, Thi Hien Tran, Daniel S. C. Butler, Michele Cavalera, Murphy Lam Yim Wan, Shahram Ahmadi, Catharina Svanborg
Pathogens. 2024 Jan; 13(1): 42. Published online 2023 Dec 31. doi: 10.3390/pathogens13010042
PMCID:
PMC10820880
AbstractArticlePDF–4.1M
4.
NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner
Mégane Nascimento, Sarah Huot-Marchand, Manoussa Fanny, Marjolène Straube, Marc Le Bert, Florence Savigny, Lionel Apetoh, Jacques Van Snick, Fabrice Trovero, Mathias Chamaillard, Valérie F. J. Quesniaux, Bernhard Ryffel, Philippe Gosset, Aurélie Gombault, Nicolas Riteau, Harry Sokol, Isabelle Couillin
Front Immunol. 2023; 14: 1224383. Published online 2023 Dec 11. doi: 10.3389/fimmu.2023.1224383
PMCID:
PMC10749332
AbstractArticlePDF–8.1M
5.
Apoptotic signaling clears engineered Salmonella in an organ-specific manner
Taylor J Abele, Zachary P Billman, Lupeng Li, Carissa K Harvest, Alexia K Bryan, Gabrielle R Magalski, Joseph P Lopez, Heather N Larson, Xiao-Ming Yin, Edward A Miao
eLife. 2023; 12: RP89210. Published online 2023 Dec 6. doi: 10.7554/eLife.89210
PMCID:
PMC10699806
AbstractArticlePDF–4.4M
6.
ASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler’s murine encephalomyelitis virus
Dandan Li, Melanie Bühler, Sandra Runft, Gisa Gerold, Katarzyna Marek, Wolfgang Baumgärtner, Till Strowig, Ingo Gerhauser
Sci Rep. 2023; 13: 10960. Published online 2023 Jul 6. doi: 10.1038/s41598-023-38152-3
PMCID:
PMC10326010
AbstractArticlePDF–4.1M
7.
IL11 activates the placental inflammasome to drive preeclampsia
Ellen Menkhorst, Leilani L. Santos, Wei Zhou, Guannan Yang, Amy L. Winship, Katarzyna E. Rainczuk, Philana Nguyen, Jian-Guo Zhang, Paddy Moore, Michelle Williams, Kim-Anh Lê Cao, Ashley Mansell, Evdokia Dimitriadis
Front Immunol. 2023; 14: 1175926. Published online 2023 May 24. doi: 10.3389/fimmu.2023.1175926
PMCID:
PMC10244672
AbstractArticlePDF–15M
8.
Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity
Ravi Bharadwaj, Christina F. Lusi, Siavash Mashayekh, Abhinit Nagar, Okuda, Amanda Monahan, Donggi Paik, Anubhab Nandy, Madison V. Anonick, William E. Goldman, Thirumala-Devi Kanneganti, Megan H. Orzalli, Catherine Leimkuhler Grimes, Prabhani U. Atukorale, Neal Silverman
Immunity. Author manuscript; available in PMC 2024 May 9.
Published in final edited form as: Immunity. 2023 May 9; 56(5): 998–1012.e8. Published online 2023 Apr 27. doi: 10.1016/j.immuni.2023.04.001
PMCID:
PMC10195032
AbstractArticlePDF–2.5M
9.
The adjuvant combination of dmLT and MPL-A activates the canonical, non-pyroptotic NLRP3 inflammasome in dendritic cells and significantly interact to expand antigen-specific CD4 T cells
David L. Bauer, Louay Bachnak, Vanessa M. Limbert, Rebecca M. Horowitz, Robin L. Baudier, Shaina J D’Souza, Victoria E. Immethun, Jonathan R Kurtz, Samuel B. Grant, James B. McLachlan
J Immunol. Author manuscript; available in PMC 2024 May 15.
Published in final edited form as: J Immunol. 2023 May 15; 210(10): 1519–1530. doi: 10.4049/jimmunol.2200221
PMCID:
PMC10159919
AbstractArticlePDF–1.7M
10.
ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery
Manuel O. Jakob, Daniel Spari, Daniel Sànchez Taltavull, Lilian Salm, Bahtiyar Yilmaz, Rémi Doucet Ladevèze, Catherine Mooser, David Pereyra, Ye Ouyang, Theresa Schmidt, Irene Mattiola, Patrick Starlinger, Deborah Stroka, Franziska Tschan, Daniel Candinas, Georg Gasteiger, Christoph S.N. Klose, Andreas Diefenbach, Mercedes Gomez de Agüero, Guido Beldi
Cell Rep. 2023 Mar 28; 42(3): 112269. Published online 2023 Mar 17. doi: 10.1016/j.celrep.2023.112269
PMCID:
PMC10066576
AbstractArticle
11.
Cigarette smoke depletes alveolar macrophages and delays clearance of Legionella pneumophila
Markus Fleischmann, Andrew G. Jarnicki, Andrew S. Brown, Chao Yang, Gary P. Anderson, Natalio Garbi, Elizabeth L. Hartland, Ian R. van Driel, Garrett Z. Ng
Am J Physiol Lung Cell Mol Physiol. 2023 Mar 1; 324(3): L373–L384. Published online 2023 Jan 31. doi: 10.1152/ajplung.00268.2022
PMCID:
PMC10026984
AbstractArticle
12.
Inhibition of CD82 improves colitis by increasing NLRP3 deubiquitination by BRCC3
Jae-Sung Kim, Hyo Keun Kim, Joongho Lee, Sein Jang, Euni Cho, Seok-Jun Mun, Seokhyun Yoon, Chul-Su Yang
Cell Mol Immunol. 2023 Feb; 20(2): 189–200. Published online 2023 Jan 5. doi: 10.1038/s41423-022-00971-1
PMCID:
PMC9887069
AbstractArticlePDF–5.0M
13.
DPP9 deficiency: an Inflammasomopathy which can be rescued by lowering NLRP1/IL-1 signaling
Cassandra R. Harapas, Kim S. Robinson, Kenneth Lay, Jasmine Wong, Ricardo Moreno Traspas, Nasrin Nabavizadeh, Annick Rass-Rothschild, Bertrand Boisson, Scott B. Drutman, Pawat Laohamonthonkul, Devon Bonner, Jingwei Rachel Xiong, Mark D. Gorrell, Sophia Davidson, Chien-Hsiung Yu, Mark D. Fleming, Jonas Gudera, Jerry Stein, Miriam Ben-Harosh, Emily Groopman, Akiko Shimamura, Hannah Tamary, Hülya Kayserili, Nevin Hatipoğlu, Jean-Laurent Casanova, Jonathan A. Bernstein, Franklin L. Zhong, Seth L. Masters, Bruno Reversade
Sci Immunol. Author manuscript; available in PMC 2023 Mar 16.
Published in final edited form as: Sci Immunol. 2022 Sep 16; 7(75): eabi4611. Published online 2022 Sep 16. doi: 10.1126/sciimmunol.abi4611
PMCID:
PMC9844213
AbstractArticlePDF–1.7M
14.
Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
Changhoon Oh, Lupeng Li, Ambika Verma, Arianna D. Reuven, Edward A. Miao, James B. Bliska, Youssef Aachoui
Cell Rep. Author manuscript; available in PMC 2023 Jan 9.
Published in final edited form as: Cell Rep. 2022 Nov 22; 41(8): 111688. doi: 10.1016/j.celrep.2022.111688
PMCID:
PMC9827617
AbstractArticlePDF–1.1M
15.
Role of Caspases and Gasdermin A during HSV-1 Infection in Mice
Lupeng Li, Stephen B. Kovacs, Ine Jørgensen, Heather N. Larson, Helen M. Lazear, Edward A. Miao
Viruses. 2022 Sep; 14(9): 2034. Published online 2022 Sep 13. doi: 10.3390/v14092034
PMCID:
PMC9504851
AbstractArticlePDF–2.2M
16.
Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation
Ting Xu, Weiwei Yu, Hui Fang, Zhen Wang, Zhexu Chi, Xingchen Guo, Danlu Jiang, Kailian Zhang, Sheng Chen, Mobai Li, Yuxian Guo, Jian Zhang, Dehang Yang, Qianzhou Yu, Di Wang, Xue Zhang
Cell Death Differ. 2022 Aug; 29(8): 1582–1595. Published online 2022 Feb 2. doi: 10.1038/s41418-022-00947-8
PMCID:
PMC9345978
AbstractArticlePDF–3.6M
17.
Pycard and BC017158 Candidate Genes of Irm1 Locus Modulate Inflammasome Activation for IL-1β Production
Andrea Borrego, Francesca Colombo, Jean Gabriel de Souza, José Ricardo Jensen, Alice Dassano, Rocco Piazza, Barbara Anaís Rodrigues dos Santos, Orlando Garcia Ribeiro, Marcelo De Franco, Wafa Hanna Koury Cabrera, Marcelo Yudi Icimoto, Nancy Starobinas, Geraldo Magalhães, Leticia Figueiredo Monteleone, Silas Fernandes Eto, Carlos DeOcesano-Pereira, Mauricio Barbugiani Goldfeder, Kerly Fernanda Mesquita Pasqualoto, Tommaso A. Dragani, Olga Célia Martinez Ibañez
Front Immunol. 2022; 13: 899569. Published online 2022 Jun 21. doi: 10.3389/fimmu.2022.899569
PMCID:
PMC9254735
AbstractArticlePDF–17M
18.
USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3
Baoshan Cai, Jian Zhao, Yuling Zhang, Yaxing Liu, Chunhong Ma, Fan Yi, Yi Zheng, Lei Zhang, Tian Chen, Huiqing Liu, Bingyu Liu, Chengjiang Gao
Autophagy. 2022; 18(5): 990–1004. Published online 2021 Sep 5. doi: 10.1080/15548627.2021.1965426
PMCID:
PMC9196652
AbstractArticlePDF–5.0M
19.
TH17 cells promote CNS inflammation by sensing danger signals via Mincle
Quanri Zhang, Weiwei Liu, Han Wang, Hao Zhou, Katarzyna Bulek, Xing Chen, Cun-Jin Zhang, Junjie Zhao, Renliang Zhang, Caini Liu, Zizhen Kang, Robert A. Bermel, George Dubyak, Derek W. Abbott, Tsan Sam Xiao, Laura E. Nagy, Xiaoxia Li
Nat Commun. 2022; 13: 2406. Published online 2022 May 3. doi: 10.1038/s41467-022-30174-1
PMCID:
PMC9064974
AbstractArticlePDF–1.9M
20.
Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon
Alejandro Peñin-Franch, José Antonio García-Vidal, Carlos Manuel Martínez, Pilar Escolar-Reina, Rosa M Martínez-Ojeda, Ana I Gómez, Juan M Bueno, Francisco Minaya-Muñoz, Fermín Valera-Garrido, Francesc Medina-Mirapeix, Pablo Pelegrín
eLife. 2022; 11: e73675. Published online 2022 Feb 24. doi: 10.7554/eLife.73675
PMCID:
PMC8896827
AbstractArticlePDF–1.4M

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