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Items: 1 to 20 of 31

1.
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates
Moritz Mall, Michael S. Kareta, Soham Chanda, Henrik Ahlenius, Nicholas Perotti, Bo Zhou, Sarah D. Grieder, Xuecai Ge, Sienna Drake, Cheen Euong Ang, Brandon M. Walker, Thomas Vierbuchen, Daniel R. Fuentes, Philip Brennecke, Kazuhiro R. Nitta, Arttu Jolma, Lars M. Steinmetz, Jussi Taipale, Thomas C. Südhof, Marius Wernig
Nature. Author manuscript; available in PMC 2024 Aug 27.
Published in final edited form as: Nature. 2017 Apr 13; 544(7649): 245–249. Published online 2017 Apr 5. doi: 10.1038/nature21722
PMCID:
PMC11348803
AbstractArticlePDF–5.5M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention
Bettina Weigel, Jana F. Tegethoff, Sarah D. Grieder, Bryce Lim, Bhuvaneswari Nagarajan, Yu-Chao Liu, Jule Truberg, Dimitris Papageorgiou, Juan M. Adrian-Segarra, Laura K. Schmidt, Janina Kaspar, Eric Poisel, Elisa Heinzelmann, Manu Saraswat, Marleen Christ, Christian Arnold, Ignacio L. Ibarra, Joaquin Campos, Jeroen Krijgsveld, Hannah Monyer, Judith B. Zaugg, Claudio Acuna, Moritz Mall
Mol Psychiatry. 2023; 28(5): 2122–2135. Published online 2023 Feb 14. doi: 10.1038/s41380-023-01959-7
PMCID:
PMC10575775
AbstractArticlePDF–9.5M
4.
The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer
Luis Puelles, Matias Hidalgo-Sánchez
Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769
PMCID:
PMC10253667
AbstractArticlePDF–6.8M
5.
MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain
Jiayang Chen, Nicole A. Fuhler, Kevin K. Noguchi, Joseph D. Dougherty
Genome Res. 2023 Apr; 33(4): 541–556. doi: 10.1101/gr.277413.122
PMCID:
PMC10234307
AbstractArticlePDF–13M
6.
Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice
Markus Wöhr, Wendy M. Fong, Justyna A. Janas, Moritz Mall, Christian Thome, Madhuri Vangipuram, Lingjun Meng, Thomas C. Südhof, Marius Wernig
Mol Autism. 2022; 13: 19. Published online 2022 May 10. doi: 10.1186/s13229-022-00497-3
PMCID:
PMC9087967
AbstractArticlePDF–4.9M
7.
Molecular Logic of Cellular Diversification in the Mouse Cerebral Cortex
Daniela J. Di Bella, Ehsan Habibi, Robert R. Stickels, Gabriele Scalia, Juliana Brown, Payman Yadollahpour, Sung Min Yang, Catherine Abbate, Tommasso Biancalani, Evan Z. Macosko, Fei Chen, Aviv Regev, Paola Arlotta
Nature. Author manuscript; available in PMC 2022 Apr 13.
Published in final edited form as: Nature. 2021 Jul; 595(7868): 554–559. Published online 2021 Jun 23. doi: 10.1038/s41586-021-03670-5
Correction in:
Nature. 2021 Aug 2
PMCID:
PMC9006333
AbstractArticlePDF–7.2M
8.
A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
Jiayang Chen, Mary E. Lambo, Xia Ge, Joshua T. Dearborn, Yating Liu, Katherine B. McCullough, Raylynn G. Swift, Dora R. Tabachnick, Lucy Tian, Kevin Noguchi, Joel R. Garbow, John N. Constantino, Harrison W. Gabel, Keith B. Hengen, Susan E. Maloney, Joseph D. Dougherty
Neuron. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3775–3792.e14. Published online 2021 Oct 5. doi: 10.1016/j.neuron.2021.09.009
Correction in:
Neuron. 2024 Jul 3; 112(13): 2257.
PMCID:
PMC8668036
AbstractArticlePDF–1.7M
9.
Foxp1 regulates neural stem cell self-renewal and bias toward deep layer cortical fates
Caroline Alayne Pearson, Destaye M. Moore, Haley O. Tucker, Joseph D. Dekker, Hui Hu, Amaya Miquelajáuregui, Bennett G. Novitch
Cell Rep. Author manuscript; available in PMC 2021 Aug 28.
Published in final edited form as: Cell Rep. 2020 Feb 11; 30(6): 1964–1981.e3. doi: 10.1016/j.celrep.2020.01.034
PMCID:
PMC8397815
AbstractArticlePDF–4.0M
10.
Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis
Cristine R. Casingal, Takako Kikkawa, Hitoshi Inada, Yukio Sasaki, Noriko Osumi
Mol Brain. 2020; 13: 167. Published online 2020 Dec 16. doi: 10.1186/s13041-020-00706-1
PMCID:
PMC7739466
AbstractArticlePDF–1.5M
11.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
12.
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System
Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund
Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005
PMCID:
PMC6381388
AbstractArticle
13.
Synaptotagmin 4 regulates pancreatic β-cell maturation by modulating the Ca2+ sensitivity of insulin secretion vesicles
Chen Huang, Emily M. Walker, Prasanna K. Dadi, Ruiying Hu, Yanwen Xu, Wenjian Zhang, Tiziana Sanavia, Jisoo Mun, Jennifer Liu, Gopika G. Nair, Tan Hwee Yim Angeline, Sui Wang, Mark A. Magnuson, Christian J. Stoeckert, Jr, Matthias Hebrok, Maureen Gannon, Weiping Han, Roland Stein, David A. Jacobson, Guoqiang Gu
Dev Cell. Author manuscript; available in PMC 2019 May 7.
Published in final edited form as: Dev Cell. 2018 May 7; 45(3): 347–361.e5. Published online 2018 Apr 12. doi: 10.1016/j.devcel.2018.03.013
PMCID:
PMC5962294
AbstractArticlePDF–4.0M
14.
Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination
Yanqing Shi, Qi Shao, Zhenghao Li, Ginez A. Gonzalez, Fengfeng Lu, Dan Wang, Yingyan Pu, Aijun Huang, Chao Zhao, Cheng He, Li Cao
Neurosci Bull. 2018 Apr; 34(2): 247–260. Published online 2018 Feb 3. doi: 10.1007/s12264-018-0207-9
PMCID:
PMC5856724
AbstractArticlePDF–3.4M
15.
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
J. Gray Camp, Farhath Badsha, Marta Florio, Sabina Kanton, Tobias Gerber, Michaela Wilsch-Bräuninger, Eric Lewitus, Alex Sykes, Wulf Hevers, Madeline Lancaster, Juergen A. Knoblich, Robert Lachmann, Svante Pääbo, Wieland B. Huttner, Barbara Treutlein
Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51): 15672–15677. Published online 2015 Dec 7. doi: 10.1073/pnas.1520760112
PMCID:
PMC4697386
AbstractArticlePDF–2.7M
16.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
17.
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3
Anna B. Osipovich, Qiaoming Long, Elisabetta Manduchi, Rama Gangula, Susan B. Hipkens, Judsen Schneider, Tadashi Okubo, Christian J. Stoeckert, Jr, Shinji Takada, Mark A. Magnuson
Development. 2014 Aug; 141(15): 2939–2949. doi: 10.1242/dev.104810
PMCID:
PMC4197673
AbstractArticle
18.
Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons
Orly L. Wapinski, Thomas Vierbuchen, Kun Qu, Qian Yi Lee, Soham Chanda, Daniel R. Fuentes, Paul G. Giresi, Yi Han Ng, Samuele Marro, Norma F. Neff, Daniela Drechsel, Ben Martynoga, Diogo S. Castro, Ashley E. Webb, Anne Brunet, Francois Guillemot, Howard Y. Chang, Marius Wernig
Cell. Author manuscript; available in PMC 2014 Oct 24.
Published in final edited form as: Cell. 2013 Oct 24; 155(3): 10.1016/j.cell.2013.09.028. Published online 2013 Oct 24. doi: 10.1016/j.cell.2013.09.028
PMCID:
PMC3871197
AbstractArticlePDF–3.3M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract
Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith
Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130
PMCID:
PMC3439845
AbstractArticlePDF–1.4M

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