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Select item 115808351.

Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation

Junichi Tanaka, Akihiro Miura, Yuko Shimamura, Youngmin Hwang, Dai Shimizu, Yuri Kondo, Anri Sawada, Hemanta Sarmah, Zurab Ninish, Kenji Mishima, Munemasa Mori

Cell Rep. Author manuscript; available in PMC 2024 Nov 21.

Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114340. Published online 2024 Jun 11. doi: 10.1016/j.celrep.2024.114340

PMCID:: PMC11580835

Abstract Article PDF–2.8M

Select item 113659542.

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation

Vaishali N. Patel, Marit H. Aure, Sophie H. Choi, James R. Ball, Ethan D. Lane, Zhangjie Wang, Yongmei Xu, Changyu Zheng, Xibao Liu, Daniel Martin, Jillian Y. Pailin, Michaela Prochazkova, Ashok B. Kulkarni, Toin H. van Kuppevelt, Indu S. Ambudkar, Jian Liu, Matthew P. Hoffman

Nat Commun. 2024; 15: 7584. Published online 2024 Aug 31. doi: 10.1038/s41467-024-51862-0

Correction in:: Nat Commun. 2024; 15: 8784.

PMCID:: PMC11365954

Abstract Article PDF–5.0M

Select item 112161733.

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development

James F. Clark, Philippe Soriano

Genes Dev. 2024 May 1; 38(9-10): 393–414. doi: 10.1101/gad.351593.124

PMCID:: PMC11216173

Abstract Article PDF–17M

Select item 112050834.

Harderian Gland Development and Degeneration in the Fgf10-Deficient Heterozygous Mouse

Shiori Ikeda, Keita Sato, Hirofumi Fujita, Hitomi Ono-Minagi, Satoru Miyaishi, Tsutomu Nohno, Hideyo Ohuchi

J Dev Biol. 2024 Jun; 12(2): 16. Published online 2024 Jun 3. doi: 10.3390/jdb12020016

PMCID:: PMC11205083

Abstract Article PDF–17M

Select item 110146575.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109635806.

Multiscale mechanical characterisation of the craniofacial system under external forces

Marius Didziokas, Dominic Jones, Ali Alazmani, Miranda Steacy, Erwin Pauws, Mehran Moazen

Biomech Model Mechanobiol. 2024; 23(2): 675–685. Published online 2024 Jan 13. doi: 10.1007/s10237-023-01799-y

PMCID:: PMC10963580

Abstract Article PDF–3.6M

Select item 109057467.

BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation

Rachel E. Musa, Kaitlyn L. Lester, Gabrielle Quickstad, Sara Vardabasso, Trevor V. Shumate, Ryan T. Salcido, Kai Ge, Karl B. Shpargel

Development. 2024 Jan 15; 151(2): dev202110. Published online 2024 Jan 24. doi: 10.1242/dev.202110

PMCID:: PMC10905746

Abstract Article

Select item 105916728.

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

Natalia A. Veniaminova, Yunlong Y. Jia, Adrien M. Hartigan, Thomas J. Huyge, Shih-Ying Tsai, Marina Grachtchouk, Seitaro Nakagawa, Andrzej A. Dlugosz, Scott X. Atwood, Sunny Y. Wong

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113121. Published online 2023 Sep 19. doi: 10.1016/j.celrep.2023.113121

PMCID:: PMC10591672

Abstract Article PDF–3.4M

Select item 105772789.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 1057681110.

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation

Marit H. Aure, Jennifer M. Symonds, Carlos U. Villapudua, Joshua T. Dodge, Sabine Werner, Wendy M. Knosp, Matthew P. Hoffman

Nat Commun. 2023; 14: 6485. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42243-0

PMCID:: PMC10576811

Abstract Article PDF–17M

Select item 1054568211.

FGF10 mitigates doxorubicin-induced myocardial toxicity in mice via activation of FGFR2b/PHLDA1/AKT axis

De-pu Zhou, Lian-cheng Deng, Xiao Feng, Hui-jing Xu, Ye Tian, Wei-wei Yang, Ping-ping Zeng, Li-hui Zou, Xi-hua Yan, Xia-yan Zhu, Dan-hua Shu, Qiang Guo, Xiao-ying Huang, Saverio Bellusci, Zhenkun Lou, Xiao-kun Li, Jin-San Zhang

Acta Pharmacol Sin. 2023 Oct; 44(10): 2004–2018. Published online 2023 May 24. doi: 10.1038/s41401-023-01101-x

PMCID:: PMC10545682

Abstract Article PDF–7.0M

Select item 1054124012.

Role of Fibroblast Growth Factor Receptor 2 (FGFR2) in Corneal Stromal Thinning

Roy Joseph, Akosua Boateng, Om P. Srivastava, Roswell R. Pfister

Invest Ophthalmol Vis Sci. 2023 Sep; 64(12): 40. Published online 2023 Sep 26. doi: 10.1167/iovs.64.12.40

PMCID:: PMC10541240

Abstract Article PDF–3.2M

Select item 1052474713.

Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death

Kendra K. Wernlé, Michael A. Sonnenfelt, Connor C. Leek, Elahe Ganji, Anna Lia Sullivan, Claudia Offutt, Jordan Shuff, David M. Ornitz, Megan L. Killian

Dev Dyn. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Dev Dyn. 2023 Sep; 252(9): 1180–1188. Published online 2023 May 22. doi: 10.1002/dvdy.600

PMCID:: PMC10524747

Abstract Article PDF–1.0M

Select item 1040364014.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 1039920315.

FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development

James F. Clark, Philippe Soriano

Biol Open. 2023 Jul 15; 12(7): bio059942. Published online 2023 Jul 27. doi: 10.1242/bio.059942

PMCID:: PMC10399203

Abstract Article PDF–6.3M

Select item 1035896716.

Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo

Marcelo D. Goissis, Brian Bradshaw, Eszter Posfai, Janet Rossant

PLoS One. 2023; 18(7): e0279515. Published online 2023 Jul 20. doi: 10.1371/journal.pone.0279515

PMCID:: PMC10358967

Abstract Article PDF–1.5M

Select item 1031728317.

Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model

Xiaowei Yang, Xingwu Zhong, Andrew JW. Huang, Lixing W. Reneker

Ocul Surf. Author manuscript; available in PMC 2023 Jul 3.

Published in final edited form as: Ocul Surf. 2022 Oct; 26: 300–309. Published online 2021 Nov 16. doi: 10.1016/j.jtos.2021.11.005

PMCID:: PMC10317283

Abstract Article PDF–3.5M

Select item 1026824018.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120