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Items: 1 to 20 of 107

1.
Reduction of human T‐cell leukemia virus type‐1 infection in mice lacking nuclear factor‐κB‐inducing kinase
Takayuki Nitta, Masakazu Tanaka, Binlian Sun, Eiji Sugihara, Mako Kimura, Yuhei Kamada, Hideto Takahashi, Shuji Hanai, Shi‐Wen Jiang, Jun–ichi Fujisawa, Masanao Miwa
Cancer Sci. 2008 May; 99(5): 872–878. Published online 2008 Feb 28. doi: 10.1111/j.1349-7006.2008.00766.x
PMCID:
PMC11160047
AbstractArticlePDF–115K
2.
Inhibition of non-canonical NF-κB signaling suppresses periodontal inflammation and bone loss
Tsukasa Aoki, Fumitaka Hiura, Aonan Li, Nan Yang, Nana Takakura-Hino, Satoru Mukai, Miho Matsuda, Fusanori Nishimura, Eijiro Jimi
Front Immunol. 2023; 14: 1179007. Published online 2023 Apr 18. doi: 10.3389/fimmu.2023.1179007
PMCID:
PMC10151688
AbstractArticlePDF–8.9M
3.
Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice
Cheng Xu, Hongyi Zhou, Yulan Jin, Khushboo Sahay, Anna Robicsek, Yisong Liu, Kunzhe Dong, Jiliang Zhou, Amanda Barrett, Huabo Su, Weiqin Chen
Nat Commun. 2022; 13: 7782. Published online 2022 Dec 16. doi: 10.1038/s41467-022-35525-6
PMCID:
PMC9758150
AbstractArticlePDF–9.5M
4.
NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition
Anna Juliane Vesting, Alexander Jais, Paul Klemm, Lukas Steuernagel, Peter Wienand, Morten Fog-Tonnesen, Henning Hvid, Anna–Lena Schumacher, Christian Kukat, Hendrik Nolte, Theodoros Georgomanolis, Janine Altmüller, Manolis Pasparakis, Andreas Schmidt, Marcus Krüger, Marc Schmidt Supprian, Ari Waisman, Beate Katharina Straub, Nathanael Raschzok, Michel Bernier, Andreas L. Birkenfeld, Nadine Hövelmeyer, Jens C. Brüning, F. Thomas Wunderlich
Mol Metab. 2022 Dec; 66: 101626. Published online 2022 Nov 7. doi: 10.1016/j.molmet.2022.101626
PMCID:
PMC9676392
AbstractArticlePDF–4.0M
5.
Biliary NIK promotes ductular reaction and liver injury and fibrosis in mice
Zhiguo Zhang, Xiao Zhong, Hong Shen, Liang Sheng, Suthat Liangpunsakul, Anna S. Lok, M. Bishr Omary, Shaomeng Wang, Liangyou Rui
Nat Commun. 2022; 13: 5111. Published online 2022 Aug 30. doi: 10.1038/s41467-022-32575-8
PMCID:
PMC9427946
AbstractArticlePDF–4.5M
6.
Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma
Jennifer L. Davis, Roman Thaler, Linda Cox, Biancamaria Ricci, Heather M. Zannit, Fei Wan, Roberta Faccio, Amel Dudakovic, Andre J. van Wijnen, Deborah J. Veis
PLoS One. 2021; 16(7): e0254426. Published online 2021 Jul 22. doi: 10.1371/journal.pone.0254426
PMCID:
PMC8297882
AbstractArticlePDF–3.6M
7.
NF-κB inducing kinase maintains T cell metabolic fitness in antitumor immunity
Meidi Gu, Xiaofei Zhou, Jee Hyung Sohn, Lele Zhu, Zuliang Jie, Jin-Young Yang, Xiaofeng Zheng, Xiaoping Xie, Jie Yang, Yaoyao Shi, Hans D Brightbill, Jae Bum Kim, Jing Wang, Xuhong Cheng, Shao-Cong Sun
Nat Immunol. Author manuscript; available in PMC 2021 Jul 4.
Published in final edited form as: Nat Immunol. 2021 Feb; 22(2): 193–204. Published online 2021 Jan 4. doi: 10.1038/s41590-020-00829-6
Correction in:
Nat Immunol. 2021 Feb 11
PMCID:
PMC7855506
AbstractArticlePDF–3.2M
8.
Myeloid cell-targeted nanocarriers efficiently inhibit cellular Inhibitor of Apoptosis for cancer immunotherapy
Peter D. Koch, Christopher B. Rodell, Rainer H. Kohler, Mikael J. Pittet, Ralph Weissleder
Cell Chem Biol. Author manuscript; available in PMC 2020 Aug 12.
Published in final edited form as: Cell Chem Biol. 2020 Jan 16; 27(1): 94–104.e5. Published online 2020 Jan 2. doi: 10.1016/j.chembiol.2019.12.007
PMCID:
PMC7422681
AbstractArticlePDF–2.2M
9.
NF‐κB‐inducing kinase contributes to normal development of cortical thymic epithelial cells: its possible role in shaping a proper T‐cell repertoire
Koji Eshima, Kana Misawa, Chihiro Ohashi, Haruka Noma, Kazuya Iwabuchi
Immunology. 2020 Jun; 160(2): 198–208. Published online 2020 Apr 13. doi: 10.1111/imm.13186
PMCID:
PMC7218659
AbstractArticlePDF–1.6M
10.
Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia
Yi-Jhu Lu, Yee-Jee Jan, Bor-Sheng Ko, Shu-Man Liang, Lujen Chen, Chih-Cheng Wu, Chih-Hui Chin, Cheng-Chin Kuo, Shaw-Fang Yet, Jun-Yang Liou
Aging (Albany NY) 2020 Apr 30; 12(8): 7511–7533. Published online 2020 Apr 24. doi: 10.18632/aging.103104
PMCID:
PMC7202544
AbstractArticlePDF–2.8M
11.
Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection
Thamer A. Hamdan, Hilal Bhat, Lamin B. Cham, Tom Adomati, Judith Lang, Fanghui Li, Ali Murtaza, Cornelia Hardt, Philipp A. Lang, Vikas Duhan, Karl S. Lang
Pathogens. 2020 Feb; 9(2): 96. Published online 2020 Feb 4. doi: 10.3390/pathogens9020096
PMCID:
PMC7168624
AbstractArticlePDF–3.5M
12.
NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease
Yaru Li, Mingming Chen, Yu Zhou, Chuanfeng Tang, Wen Zhang, Ying Zhong, Yadong Chen, Hong Zhou, Liang Sheng
Theranostics. 2020; 10(8): 3579–3593. Published online 2020 Feb 18. doi: 10.7150/thno.40149
PMCID:
PMC7069072
AbstractArticlePDF–2.6M
13.
Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion
Yan Xiu, Qianze Dong, Lin Fu, Aaron Bossler, Xiaobing Tang, Brendan Boyce, Nicholas Borcherding, Mariah Leidinger, José Luis Sardina, Hai-hui Xue, Qingchang Li, Andrew Feldman, Iannis Aifantis, Francesco Boccalatte, Lili Wang, Meiling Jin, Joseph Khoury, Wei Wang, Shimin Hu, Youzhong Yuan, Endi Wang, Ji Yuan, Siegfried Janz, John Colgan, Hasem Habelhah, Thomas Waldschmidt, Markus Müschen, Adam Bagg, Benjamin Darbro, Chen Zhao
Blood. 2020 Jan 9; 135(2): 108–120. Prepublished online 2019 Oct 11. doi: 10.1182/blood.2019001438
PMCID:
PMC6952829
AbstractArticle
14.
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB
Zixu Liu, Katrina B. Mar, Natasha W. Hanners, Sofya S. Perelman, Mohammed Kanchwala, Chao Xing, John W. Schoggins, Neal M. Alto
Nature. Author manuscript; available in PMC 2019 Oct 24.
Published in final edited form as: Nature. 2019 Apr; 568(7751): 249–253. Published online 2019 Mar 20. doi: 10.1038/s41586-019-1041-6
PMCID:
PMC6812682
AbstractArticlePDF–4.2M
15.
Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization
Yanchuan Li, Jin-Young Yang, Xiaoping Xie, Zuliang Jie, Lingyun Zhang, Jianhong Shi, Daniel Lin, Meidi Gu, Xiaofei Zhou, Haiyan S. Li, Stephanie S. Watowich, Antrix Jain, Sung Yun Jung, Jun Qin, Xuhong Cheng, Shao-Cong Sun
Cell Res. 2019 Jun; 29(6): 474–485. Published online 2019 May 13. doi: 10.1038/s41422-019-0174-3
PMCID:
PMC6796864
AbstractArticlePDF–4.8M
16.
Medullary thymic epithelial NF–kB-inducing kinase (NIK)/IKKα pathway shapes autoimmunity and liver and lung homeostasis in mice
Hong Shen, Yewei Ji, Yi Xiong, Hana Kim, Xiao Zhong, Michelle G. Jin, Yatrik M. Shah, M. Bishr Omary, Yong Liu, Ling Qi, Liangyou Rui
Proc Natl Acad Sci U S A. 2019 Sep 17; 116(38): 19090–19097. Published online 2019 Sep 3. doi: 10.1073/pnas.1901056116
PMCID:
PMC6754592
AbstractArticlePDF–2.7M
17.
Excess NF-κB Induces Ectopic Odontogenesis in Embryonic Incisor Epithelium
J. Blackburn, K. Kawasaki, T. Porntaveetus, M. Kawasaki, Y. Otsuka-Tanaka, Y. Miake, M.S. Ota, M. Watanabe, M. Hishinuma, T. Nomoto, S. Oommen, S. Ghafoor, F. Harada, K. Nozawa-Inoue, T. Maeda, R. Peterková, H. Lesot, J. Inoue, T. Akiyama, R. Schmidt-Ullrich, B. Liu, Y. Hu, A. Page, Á. Ramírez, P.T. Sharpe, A. Ohazama
J Dent Res. 2015 Jan; 94(1): 121–128. Published online 2014 Nov 6. doi: 10.1177/0022034514556707
PMCID:
PMC6728577
AbstractArticlePDF–1.0M
18.
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response
Sadeesh K. Ramakrishnan, Huabing Zhang, Xiaoya Ma, Inkyung Jung, Andrew J. Schwartz, Daniel Triner, Samantha N. Devenport, Nupur K. Das, Xiang Xue, Melody Y. Zeng, Yinling Hu, Richard M. Mortensen, Joel K Greenson, Marilia Cascalho, Christiane E. Wobus, Justin A. Colacino, Gabriel Nunez, Liangyou Rui, Yatrik M. Shah
Nat Commun. 2019; 10: 660. Published online 2019 Feb 8. doi: 10.1038/s41467-019-08581-8
PMCID:
PMC6368617
AbstractArticlePDF–4.2M
19.
Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice
Xinzhi Li, Linna Jia, Xiaoyue Chen, Ying Dong, Xiaomeng Ren, Yuefan Dong, Ying Chen, Liwei Xie, Ming Liu, Chiyo Shiota, George K. Gittes, Liangyou Rui, Zheng Chen
Theranostics. 2018; 8(21): 5960–5971. Published online 2018 Nov 13. doi: 10.7150/thno.28960
PMCID:
PMC6299425
AbstractArticlePDF–2.2M
20.
Hippo/Mst signaling couples metabolic state and immune function of CD8α+ dendritic cells
Xingrong Du, Jing Wen, Yanyan Wang, Peer Karmaus, Alireza Khatamian, Haiyan Tan, Yuxin Li, Cliff Guy, Thanh-Long M. Nguyen, Yogesh Dhungana, Geoffrey Neale, Junmin Peng, Jiyang Yu, Hongbo Chi
Nature. Author manuscript; available in PMC 2018 Dec 13.
Published in final edited form as: Nature. 2018 Jun; 558(7708): 141–145. Published online 2018 May 30. doi: 10.1038/s41586-018-0177-0
PMCID:
PMC6292204
AbstractArticlePDF–4.3M

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