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Items: 1 to 20 of 39

1.
Decreased Tiam1‐mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia
Yi Wu, Wei Liu, Jia Li, Hang Shi, Shize Ma, Di Wang, Bo Pan, Ran Xiao, Haiyue Jiang, Xia Liu
J Cell Mol Med. 2024 Jun; 28(11): e18443. Published online 2024 Jun 4. doi: 10.1111/jcmm.18443
PMCID:
PMC11149491
AbstractArticlePDF–29M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses
Nikhil Sharma, Patricia Kessler, Ganes C. Sen
J Virol. 2023 Dec; 97(12): e01304-23. Published online 2023 Nov 20. doi: 10.1128/jvi.01304-23
PMCID:
PMC10734550
AbstractArticlePDF–913K
4.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
5.
PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c
Asli E. Dogan, Syed M. Hamid, Asli D. Yildirim, Zehra Yildirim, Ganes Sen, Celine E. Riera, Roberta A. Gottlieb, Ebru Erbay
J Biol Chem. 2022 Jul; 298(7): 102050. Published online 2022 May 19. doi: 10.1016/j.jbc.2022.102050
PMCID:
PMC9218515
AbstractArticlePDF–1.2M
6.
Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells
Chandan Gurung, Mona Fendereski, Krishna Sapkota, Jason Guo, Faqing Huang, Yan-Lin Guo
J Biol Chem. 2021 Jan-Jun; 296: 100264. Published online 2021 Jan 8. doi: 10.1016/j.jbc.2021.100264
PMCID:
PMC7948645
AbstractArticlePDF–1.7M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling
Lauren S. Vaughn, Evelyn Chukwurah, Rekha C Patel
Biochem J. Author manuscript; available in PMC 2022 Feb 12.
Published in final edited form as: Biochem J. 2021 Feb 12; 478(3): 493–510. doi: 10.1042/BCJ20200987
PMCID:
PMC7919947
AbstractArticlePDF–1.6M
9.
A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells
Kazuhiro Murakami, Yumi Terakado, Kikue Saito, Yoshie Jomen, Haruna Takeda, Masanobu Oshima, Nick Barker
Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2016806118. Published online 2021 Jan 21. doi: 10.1073/pnas.2016806118
PMCID:
PMC7848749
AbstractArticlePDF–3.2M
10.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
11.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
12.
PKR modulates abnormal brain signaling in experimental obesity
Mariko Taga, François Mouton-Liger, Malha Sadoune, Sarah Gourmaud, Jenny Norman, Marion Tible, Sylvie Thomasseau, Claire Paquet, James A. R. Nicoll, Delphine Boche, Jacques Hugon
PLoS One. 2018; 13(5): e0196983. Published online 2018 May 24. doi: 10.1371/journal.pone.0196983
PMCID:
PMC5968403
AbstractArticlePDF–15M
13.
Functional Redundancy of DICER Cofactors TARBP2 and PRKRA During Murine Embryogenesis Does Not Involve miRNA Biogenesis
Sri Ramulu N. Pullagura, Bill Buaas, Nichelle Gray, Lindsey C. Krening, Anuj Srivastava, Robert E. Braun
Genetics. 2018 Apr; 208(4): 1513–1522. Published online 2018 Feb 21. doi: 10.1534/genetics.118.300791
PMCID:
PMC5887145
AbstractArticlePDF–1.3M
14.
Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology
Kristina Palmer, Heather Fairfield, Suhaib Borgeia, Michelle Curtain, Mohamed G. Hassan, Louise Dionne, Son Yong Karst, Harold Coombs, Laura G. Reinholdt, David E. Bergstrom, Leah Rae Donahue, Timothy C. Cox, Stephen A. Murray
Dev Biol. Author manuscript; available in PMC 2017 Jul 15.
Published in final edited form as: Dev Biol. 2016 Jul 15; 415(2): 216–227. Published online 2015 Jul 31. doi: 10.1016/j.ydbio.2015.07.023
PMCID:
PMC4733616
AbstractArticlePDF–827K
15.
The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development
Benjamin K. Dickerman, Christine L. White, Patricia M. Kessler, Anthony J. Sadler, Bryan R.G. Williams, Ganes C. Sen
FEBS J. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: FEBS J. 2015 Dec; 282(24): 4766–4781. Published online 2015 Oct 26. doi: 10.1111/febs.13533
PMCID:
PMC4715520
AbstractArticlePDF–2.1M
16.
PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load
David Chun-Hei Poon, Yuen-Shan Ho, Ran You, Hei-Long Tse, Kin Chiu, Raymond Chuen-Chung Chang
J Neuroinflammation. 2015; 12: 212. Published online 2015 Nov 19. doi: 10.1186/s12974-015-0433-2
PMCID:
PMC4653925
AbstractArticlePDF–1.5M
17.
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders
Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt
Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114
PMCID:
PMC4484392
AbstractArticlePDF–604K
18.
PACT/RAX Regulates the Migration of Cerebellar Granule Neurons in the Developing Cerebellum
Yue Yong, Ya Meng, Hanqing Ding, Zhiqin Fan, Yifen Tang, Chenghua Zhou, Jia Luo, Zun-Ji Ke
Sci Rep. 2015; 5: 7961. Published online 2015 Jan 22. doi: 10.1038/srep07961
PMCID:
PMC4302322
AbstractArticlePDF–8.8M
19.
Essential Role of PACT-Mediated PKR Activation in Tunicamycin-induced Apoptosis
Madhurima Singh, Vennese Fowlkes, Indhira Handy, Chandrashekhar V. Patel, Rekha C. Patel
J Mol Biol. Author manuscript; available in PMC 2014 May 19.
Published in final edited form as: J Mol Biol. 2009 Jan 16; 385(2): 457–468. Published online 2008 Nov 5. doi: 10.1016/j.jmb.2008.10.068
PMCID:
PMC4026198
AbstractArticlePDF–2.2M
20.
The Protein Kinase PKR is Critical for LPS-induced iNOS Production, but Dispensable for Inflammasome Activation in Macrophages
Yuan He, Luigi Franchi, Gabriel Núñez
Eur J Immunol. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Eur J Immunol. 2013 May; 43(5): 1147–1152. Published online 2013 Mar 15. doi: 10.1002/eji.201243187
PMCID:
PMC3757543
AbstractArticlePDF–2.3M

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