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Items: 1 to 20 of 68

1.
A Mettl16/m6A/mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells
Yunqiao Han, Kui Sun, Shanshan Yu, Yayun Qin, Zuxiao Zhang, Jiong Luo, Hualei Hu, Liyan Dai, Manman Cui, Chaolin Jiang, Fei Liu, Yuwen Huang, Pan Gao, Xiang Chen, Tianqing Xin, Xiang Ren, Xiaoyan Wu, Jieping Song, Qing Wang, Zhaohui Tang, Jianjun Chen, Haojian Zhang, Xianqin Zhang, Mugen Liu, Daji Luo
EMBO J. 2024 May; 43(10): 1990–2014. Published online 2024 Apr 11. doi: 10.1038/s44318-024-00082-9
PMCID:
PMC11099167
AbstractArticlePDF–16M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B
Louis R. Parham, Patrick A. Williams, Kay Katada, Shaneice K. Nettleford, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Cell Mol Gastroenterol Hepatol. 2024; 17(3): 439–451. Published online 2023 Dec 9. doi: 10.1016/j.jcmgh.2023.12.001
PMCID:
PMC10835461
AbstractArticlePDF–3.1M
4.
IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis
Mayura R. Dhamdhere, Chethana P. Gowda, Vikash Singh, Zhenqiu Liu, Nicholas Carruthers, Christa N. Grant, Arati Sharma, Sinisa Dovat, Jeffrey M. Sundstrom, Hong-Gang Wang, Vladimir S. Spiegelman
Oncogene. Author manuscript; available in PMC 2023 Oct 3.
Published in final edited form as: Oncogene. 2023 May; 42(19): 1558–1571. Published online 2023 Mar 27. doi: 10.1038/s41388-023-02671-0
PMCID:
PMC10547097
AbstractArticlePDF–2.6M
5.
RNA binding protein IGF2BP1 synergizes with ETV6-RUNX1 to drive oncogenic signaling in B-cell Acute Lymphoblastic Leukemia
Gunjan Sharma, Tiffany M. Tran, Ishu Bansal, Mohammad Sabique Beg, Ruchi Bhardwaj, Jaspal Bassi, Yuande Tan, Amit Kumar Jaiswal, Christine Tso, Ayushi Jain, Jay Singh, Parthaprasad Chattopadhyay, Archna Singh, Anita Chopra, Sameer Bakhshi, David Casero, Dinesh S. Rao, Jayanth Kumar Palanichamy
J Exp Clin Cancer Res. 2023; 42: 231. Published online 2023 Sep 5. doi: 10.1186/s13046-023-02810-1
PMCID:
PMC10478443
AbstractArticlePDF–12M
6.
Inhibition of IGF2BP1 attenuates renal injury and inflammation by alleviating m6A modifications and E2F1/MIF pathway
Yan Mao, Feng Jiang, Xue-Jiao Xu, Lan-Bo Zhou, Rui Jin, Li-Li Zhuang, Chen-Xia Juan, Guo-Ping Zhou
Int J Biol Sci. 2023; 19(2): 593–609. Published online 2023 Jan 1. doi: 10.7150/ijbs.78348
PMCID:
PMC9830505
AbstractArticlePDF–33M
7.
Downregulation of METTL14 improves postmenopausal osteoporosis via IGF2BP1 dependent posttranscriptional silencing of SMAD1
Chaoqing Huang, Yuan Wang
Cell Death Dis. 2022 Nov; 13(11): 919. Published online 2022 Nov 1. doi: 10.1038/s41419-022-05362-y
PMCID:
PMC9626483
AbstractArticlePDF–6.4M
8.
Tagged actin mRNA dysregulation in IGF2BP1equation i1 mice
Leti Núñez, Adina R. Buxbaum, Zachary B. Katz, Melissa Lopez-Jones, Chiso Nwokafor, Kevin Czaplinski, Feng Pan, Jason Rosenberg, Hannah R. Monday, Robert H. Singer
Proc Natl Acad Sci U S A. 2022 Sep 13; 119(37): e2208465119. Published online 2022 Sep 6. doi: 10.1073/pnas.2208465119
PMCID:
PMC9477413
AbstractArticlePDF–1.9M
9.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
10.
The stem cell marker Prom1 promotes axon regeneration by down-regulating cholesterol synthesis via Smad signaling
Jinyoung Lee, Jung Eun Shin, Bohm Lee, Hyemin Kim, Yewon Jeon, Seung Hyun Ahn, Sung Wook Chi, Yongcheol Cho
Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15955–15966. Published online 2020 Jun 17. doi: 10.1073/pnas.1920829117
PMCID:
PMC7355016
AbstractArticlePDF–3.0M
11.
The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression
Vikash Singh, Chethana P. Gowda, Vishal Singh, Ashwinkumar S. Ganapathy, Dipti M. Karamchandani, Melanie A. Eshelman, Gregory S. Yochum, Prashant Nighot, Vladimir S. Spiegelman
J Biol Chem. 2020 Jun 19; 295(25): 8602–8612. Published online 2020 May 8. doi: 10.1074/jbc.AC120.013646
PMCID:
PMC7307209
AbstractArticlePDF–2.5M
12.
microRNA-670 modulates Igf2bp1 expression to regulate RNA methylation in parthenogenetic mouse embryonic development
Jindong Hao, Haobo Hu, Ziping Jiang, Xianfeng Yu, Chengshun Li, Lin Chen, Yidan Xia, Da Liu, Dongxu Wang
Sci Rep. 2020; 10: 4782. Published online 2020 Mar 16. doi: 10.1038/s41598-020-61816-3
PMCID:
PMC7076016
AbstractArticlePDF–2.7M
13.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
14.
β-Actin mRNA interactome mapping by proximity biotinylation
Joyita Mukherjee, Orit Hermesh, Carolina Eliscovich, Nicolas Nalpas, Mirita Franz-Wachtel, Boris Maček, Ralf-Peter Jansen
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12863–12872. Published online 2019 Jun 12. doi: 10.1073/pnas.1820737116
PMCID:
PMC6600913
AbstractArticlePDF–2.4M
15.
Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation
Léa Lepelletier, Sébastien D. Langlois, Christopher B. Kent, Kristy Welshhans, Steves Morin, Gary J. Bassell, Patricia T. Yam, Frédéric Charron
J Neurosci. 2017 Feb 15; 37(7): 1685–1695. doi: 10.1523/JNEUROSCI.3016-16.2016
PMCID:
PMC6589976
AbstractArticlePDF–2.6M
16.
Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1
Priya Chatterji, Patrick A Williams, Kelly A Whelan, Fernando C Samper, Sarah F Andres, Lauren A Simon, Louis R Parham, Rei Mizuno, Emma T Lundsmith, David SM Lee, Shun Liang, HR Sagara Wijeratne, Stefanie Marti, Lillian Chau, Veronique Giroux, Benjamin J Wilkins, Gary D Wu, Premal Shah, Gian G Tartaglia, Kathryn E Hamilton
EMBO Rep. 2019 Jun; 20(6): e47074. Published online 2019 May 6. doi: 10.15252/embr.201847074
Correction in:
EMBO Rep. 2021 Aug 4; 22(8): e47074.
PMCID:
PMC6549032
AbstractArticlePDF–2.3M
17.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
18.
The LIN28B–IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine
Priya Chatterji, Kathryn E. Hamilton, Shun Liang, Sarah F. Andres, H.R. Sagara Wijeratne, Rei Mizuno, Lauren A. Simon, Philip D. Hicks, Shawn W. Foley, Jason R. Pitarresi, Andres J. Klein-Szanto, Amanda T. Mah, Laurianne Van Landeghem, Brian D. Gregory, Christopher J. Lengner, Blair B. Madison, Premal Shah, Anil K. Rustgi
Genes Dev. 2018 Aug 1; 32(15-16): 1020–1034. doi: 10.1101/gad.314369.118
PMCID:
PMC6075153
AbstractArticlePDF–4.3M
19.
Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis
Yves Mugabo, Mina Sadeghi, Nancy N. Fang, Thibault Mayor, Gareth E. Lim
J Biol Chem. 2018 May 4; 293(18): 6736–6750. Published online 2018 Mar 12. doi: 10.1074/jbc.M117.816272
PMCID:
PMC5936800
AbstractArticlePDF–2.4M
20.
Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells
Gal Haimovich, Christopher M. Ecker, Margaret C. Dunagin, Elliott Eggan, Arjun Raj, Jeffrey E. Gerst, Robert H. Singer
Proc Natl Acad Sci U S A. 2017 Nov 14; 114(46): E9873–E9882. Published online 2017 Oct 24. doi: 10.1073/pnas.1706365114
PMCID:
PMC5699038
AbstractArticlePDF–1.5M

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