PMC Links for GEO Profiles (Select 34243520) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108298314.

Tribbles pseudokinase 3 promotes enterovirus A71 infection via dual mechanisms

Huiqiang Wang, Ke Li, Boming Cui, Haiyan Yan, Shuo Wu, Kun Wang, Ge Yang, Jiandong Jiang, Yuhuan Li

Emerg Microbes Infect. 2024; 13(1): 2307514. Published online 2024 Jan 19. doi: 10.1080/22221751.2024.2307514

PMCID:: PMC10829831

Abstract Article PDF–4.2M

Select item 106636845.

The pseudokinase TRIB3 controls adipocyte lipid homeostasis and proliferation in vitro and in vivo

Miguel Hernández-Quiles, Laura Martinez Campesino, Imogen Morris, Zabran Ilyas, Steve Reynolds, Nguan Soon Tan, Paula Sobrevals Alcaraz, Edwin C.A. Stigter, Ákos Varga, János Varga, Robert van Es, Harmjan Vos, Heather L. Wilson, Endre Kiss-Toth, Eric Kalkhoven

Mol Metab. 2023 Dec; 78: 101829. Published online 2023 Oct 30. doi: 10.1016/j.molmet.2023.101829

PMCID:: PMC10663684

Abstract Article PDF–3.5M

Select item 104329766.

Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1

Sumati Gonuguntla, Rohan K. Humphrey, Akshita Gorantla, Ergeng Hao, Ulupi S. Jhala

J Biol Chem. 2023 Aug; 299(8): 104803. Published online 2023 May 11. doi: 10.1016/j.jbc.2023.104803

PMCID:: PMC10432976

Abstract Article PDF–2.0M

Select item 103872377.

DELE1 is protective for mitochondrial cardiomyopathy

Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.

Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003

PMCID:: PMC10387237

Abstract Article PDF–661K

Select item 101501808.

TRIB3 promotes pulmonary fibrosis through inhibiting SLUG degradation by physically interacting with MDM2

Xiaoxi Lv, Shanshan Liu, Chang Liu, Yunxuan Li, Tingting Zhang, Jie Qi, Ke Li, Fang Hua, Bing Cui, Xiaowei Zhang, Yuxin Liu, Jiaojiao Yu, Jinmei Yu, Li Li, Xia Li, Zhigang Yao, Bo Huang

Acta Pharm Sin B. 2023 Apr; 13(4): 1631–1647. Published online 2023 Jan 11. doi: 10.1016/j.apsb.2023.01.008

PMCID:: PMC10150180

Abstract Article PDF–6.7M

Select item 95234919.

Mitochondrial stress induces an HRI-eIF2α pathway protective for cardiomyopathy

Siting Zhu, Anh Nguyen, Jing Pang, Jun Zhao, Ze’e Chen, Zhengyu Liang, Yusu Gu, Helen Huynh, Yutong Bao, Sharon Lee, Yuval Kluger, Kunfu Ouyang, Sylvia M Evans, Xi Fang

Circulation. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Circulation. 2022 Sep 27; 146(13): 1028–1031. Published online 2022 Sep 26. doi: 10.1161/CIRCULATIONAHA.122.059594

PMCID:: PMC9523491

Article PDF–1016K

Select item 944061110.

Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses

Jiani Li, Xuhua Tan, Qihang Sun, Xuri Li, Rongyuan Chen, Lixia Luo

Invest Ophthalmol Vis Sci. 2022 Sep; 63(10): 1. Published online 2022 Sep 1. doi: 10.1167/iovs.63.10.1

PMCID:: PMC9440611

Abstract Article PDF–10M

Select item 901455911.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 838561812.

Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy

Priyamvada M. Pitale, Irina V. Saltykova, Yvonne Adu-Agyeiwaah, Sergio Li Calzi, Takashi Satoh, Shizuo Akira, Oleg Gorbatyuk, Michael E. Boulton, Machelle T. Pardue, W. Timothy Garvey, Mohammad Athar, Maria B. Grant, Marina S. Gorbatyuk

Diabetes. 2021 Aug; 70(8): 1738–1753. Published online 2021 May 11. doi: 10.2337/db20-1268

PMCID:: PMC8385618

Abstract Article PDF–4.7M

Select item 825385913.

Tribbles homolog 3-mediated targeting the AKT/mTOR axis in mice with retinal degeneration

Irina V. Saltykova, Asif Elahi, Priyam M. Pitale, Oleg S. Gorbatyuk, Mohammad Athar, Marina S. Gorbatyuk

Cell Death Dis. 2021 Jul; 12(7): 664. Published online 2021 Jul 2. doi: 10.1038/s41419-021-03944-w

PMCID:: PMC8253859

Abstract Article PDF–4.1M

Select item 798205414.

Obesity-induced TRB3 Negatively Regulates Brown Adipose Tissue Function in Mice

Ha-Won Jeong, Ran Hee Choi, Ho-Jin Koh

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Apr 2.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Apr 2; 547: 29–35. Published online 2021 Feb 13. doi: 10.1016/j.bbrc.2021.01.103

PMCID:: PMC7982054

Abstract Article PDF–966K

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 714486616.

Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation

Xiao-Wei Zhang, Ji-Chao Zhou, Dian Peng, Fang Hua, Ke Li, Jiao-Jiao Yu, Xiao-Xi Lv, Bing Cui, Shan-Shan Liu, Jin-Mei Yu, Feng Wang, Cai-Cai Jin, Zhao-Na Yang, Chen-Xi Zhao, Xue-Ying Hou, Bo Huang, Zhuo-Wei Hu

Autophagy. 2020; 16(5): 782–796. Published online 2019 Jul 9. doi: 10.1080/15548627.2019.1635383

PMCID:: PMC7144866

Abstract Article PDF–6.5M

Select item 694785417.

Effect of the alteration of Tribbles homologue 3 expression on epithelial-mesenchymal transition of transforming growth factor β1-induced mouse alveolar epithelial cells through the Wnt/β-catenin signaling pathway

Wencheng Yu, Liyun Mi, Feifei Wang

Mol Med Rep. 2020 Feb; 21(2): 615–622. Published online 2019 Dec 5. doi: 10.3892/mmr.2019.10863

PMCID:: PMC6947854

Abstract Article PDF–752K

Select item 694490618.

Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos

Nadège Poncet, Pamela A Halley, Christopher Lipina, Marek Gierliński, Alwyn Dady, Gail A Singer, Melanie Febrer, Yun‐Bo Shi, Terry P Yamaguchi, Peter M Taylor, Kate G Storey

EMBO Rep. 2020 Jan 7; 21(1): e48469. Published online 2019 Dec 2. doi: 10.15252/embr.201948469

PMCID:: PMC6944906

Abstract Article PDF–3.5M

Select item 643665419.

TRB3 regulates skeletal muscle mass in food deprivation–induced atrophy

Ran Hee Choi, Abigail McConahay, João G. Silvestre, Anselmo S. Moriscot, James A. Carson, Ho-Jin Koh

FASEB J. 2019 Apr; 33(4): 5654–5666. Published online 2019 Jan 25. doi: 10.1096/fj.201802145RR

PMCID:: PMC6436654

Abstract Article

Select item 582845820.

Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts

Junlian Gu, Xiaoqing Yan, Xiaozhen Dai, Yuehui Wang, Qian Lin, Jian Xiao, Shanshan Zhou, Jian Zhang, Kai Wang, Jun Zeng, Ying Xin, Michelle T. Barati, Chi Zhang, Yang Bai, Yan Li, Paul N. Epstein, Kupper A. Wintergerst, Xiaokun Li, Yi Tan, Lu Cai

Diabetes. 2018 Mar; 67(3): 507–517. Published online 2017 Oct 27. doi: 10.2337/db17-0219

Correction in:: Diabetes. 2020 Feb; 69(2): 267.

PMCID:: PMC5828458

Abstract Article PDF–2.0M

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