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Items: 1 to 20 of 34

1.
Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6
Dimitrius Santiago P. S. F. Guimarães, Ninon M. F. Barrios, André Gustavo de Oliveira, David Rizo‐Roca, Maxence Jollet, Jonathon A.B. Smith, Thiago R. Araujo, Marcos Vinicius da Cruz, Emilio Marconato, Jr., Sandro M. Hirabara, André S. Vieira, Anna Krook, Juleen R. Zierath, Leonardo R. Silveira
J Cachexia Sarcopenia Muscle. 2024 Aug; 15(4): 1335–1347. Published online 2024 Apr 29. doi: 10.1002/jcsm.13480
PMCID:
PMC11294040
AbstractArticlePDF–3.8M
2.
Trefoil factor 3 can stimulate Th17 cell response in the development of type 2 diabetes mellitus
Ziyang Lin, Jinyuan Zhang, Tingting Duan, Junzheng Yang, Yiqi Yang
Sci Rep. 2024; 14: 10340. Published online 2024 May 6. doi: 10.1038/s41598-024-60426-7
PMCID:
PMC11074263
AbstractArticlePDF–4.5M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis
Wei-yu Zhou, Pei Liu, Yi-fan Xia, Yi-jie Shi, Hong-yu Xu, Meng Ding, Qi-qi Yang, Shu-wen Qian, Yan Tang, Yan Lu, Qi-qun Tang, Yang Liu
Mol Metab. 2024 Mar; 81: 101891. Published online 2024 Feb 1. doi: 10.1016/j.molmet.2024.101891
PMCID:
PMC10864868
AbstractArticlePDF–2.6M
5.
Melanoma-intrinsic NR2F6 activity regulates antitumor immunity
Hyungsoo Kim, Yongmei Feng, Rabi Murad, Joanna Pozniak, Carl Pelz, Yeqing Chen, Bhavik Dalal, Rosalie Sears, Eduard Sergienko, Michael Jackson, Eytan Ruppin, Meenhard Herlyn, Curtis Harris, Jean-Christophe Marine, Victoria Klepsch, Gottfried Baier, Ze’ev A. Ronai
Sci Adv. 2023 Jul; 9(27): eadf6621. Published online 2023 Jul 5. doi: 10.1126/sciadv.adf6621
PMCID:
PMC10321753
AbstractArticlePDF–2.0M
6.
A role for the nuclear receptor NR2F6 in peritoneal B cell homeostasis
William J. Olson, Bojana Jakic, Verena Labi, Johannes Woelk, Emmanuel Derudder, Gottfried Baier, Natascha Hermann-Kleiter
Front Immunol. 2022; 13: 845235. Published online 2022 Aug 16. doi: 10.3389/fimmu.2022.845235
PMCID:
PMC9425112
AbstractArticlePDF–7.1M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Loss of the orphan nuclear receptor NR2F6 enhances CD8+ T-cell memory via IFN-γ
Bojana Jakic, William J. Olson, Kerstin Siegmund, Victoria Klepsch, Janine Kimpel, Verena Labi, Dietmar Zehn, Gottfried Baier, Natascha Hermann-Kleiter
Cell Death Dis. 2021 Feb; 12(2): 187. Published online 2021 Feb 15. doi: 10.1038/s41419-021-03470-9
PMCID:
PMC7884426
AbstractArticlePDF–3.5M
9.
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy
Victoria Klepsch, Maria Pommermayr, Dominik Humer, Natascha Brigo, Natascha Hermann-Kleiter, Gottfried Baier
Cell Commun Signal. 2020; 18: 8. Published online 2020 Jan 14. doi: 10.1186/s12964-019-0454-z
PMCID:
PMC6961368
AbstractArticlePDF–1.9M
10.
Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21
William J. Olson, Bojana Jakic, Verena Labi, Katia Schoeler, Michaela Kind, Victoria Klepsch, Gottfried Baier, Natascha Hermann-Kleiter
Cell Rep. 2019 Sep 10; 28(11): 2878–2891.e5. Published online 2019 Sep 10. doi: 10.1016/j.celrep.2019.08.024
PMCID:
PMC6791812
AbstractArticle
11.
Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade
Victoria Klepsch, Natascha Hermann-Kleiter, Patricia Do-Dinh, Bojana Jakic, Anne Offermann, Mirjana Efremova, Sieghart Sopper, Dietmar Rieder, Anne Krogsdam, Gabriele Gamerith, Sven Perner, Alexandar Tzankov, Zlatko Trajanoski, Dominik Wolf, Gottfried Baier
Nat Commun. 2018; 9: 1538. Published online 2018 Apr 18. doi: 10.1038/s41467-018-04004-2
PMCID:
PMC5906604
AbstractArticlePDF–1.8M
12.
The Nuclear Orphan Receptor NR2F6 Suppresses Lymphocyte Activation and T Helper 17-Dependent Autoimmunity
Natascha Hermann-Kleiter, Thomas Gruber, Christina Lutz-Nicoladoni, Nikolaus Thuille, Friedrich Fresser, Verena Labi, Natalia Schiefermeier, Marei Warnecke, Lukas Huber, Andreas Villunger, Gregor Eichele, Sandra Kaminski, Gottfried Baier
Immunity. Author manuscript; available in PMC 2016 Jul 12.
Published in final edited form as: Immunity. 2008 Aug 15; 29(2): 205–216. doi: 10.1016/j.immuni.2008.06.008
PMCID:
PMC4941926
AbstractArticlePDF–2.0M
13.
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance
Natascha Hermann-Kleiter, Victoria Klepsch, Stephanie Wallner, Kerstin Siegmund, Sebastian Klepsch, Selma Tuzlak, Andreas Villunger, Sandra Kaminski, Christa Pfeifhofer-Obermair, Thomas Gruber, Dominik Wolf, Gottfried Baier
Cell Rep. 2015 Sep 29; 12(12): 2072–2085. Published online 2015 Sep 17. doi: 10.1016/j.celrep.2015.08.035
PMCID:
PMC4594157
AbstractArticle
14.
A Proteomic Analysis Reveals That Snail Regulates the Expression of the Nuclear Orphan Receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and Interleukin 17 (IL-17) to Inhibit Adipocyte Differentiation
Alberto Peláez-García, Rodrigo Barderas, Raquel Batlle, Rosa Viñas-Castells, Rubén A. Bartolomé, Sofía Torres, Marta Mendes, María Lopez-Lucendo, Rocco Mazzolini, Félix Bonilla, Antonio García de Herreros, J. Ignacio Casal
Mol Cell Proteomics. 2015 Feb; 14(2): 303–315. Published online 2014 Dec 10. doi: 10.1074/mcp.M114.045328
PMCID:
PMC4350027
AbstractArticlePDF–2.7M
15.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
16.
Ear2 Deletion Causes Early Memory and Learning Deficits in APP/PS1 Mice
Markus P. Kummer, Thea Hammerschmidt, Ana Martinez, Dick Terwel, Gregor Eichele, Anika Witten, Stefanie Figura, Monika Stoll, Stephanie Schwartz, Hans-Christian Pape, Joachim L. Schultze, David Weinshenker, Michael T. Heneka
J Neurosci. 2014 Jun 25; 34(26): 8845–8854. doi: 10.1523/JNEUROSCI.4027-13.2014
Correction in:
J Neurosci. 2015 Feb 4; 35(5): 2321.
PMCID:
PMC4147626
AbstractArticlePDF–3.0M
17.
A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors
Chun Ming Chan, Joel Fulton, Cristina Montiel-Duarte, Hilary M. Collins, Neetu Bharti, Frances R. Wadelin, Paula M. Moran, Nigel P. Mongan, David M. Heery
Nucleic Acids Res. 2013 Nov; 41(21): 9663–9679. Published online 2013 Aug 23. doi: 10.1093/nar/gkt761
PMCID:
PMC3834829
AbstractArticlePDF–3.7M
18.
Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter
Natascha Hermann-Kleiter, Marlies Meisel, Friedrich Fresser, Nikolaus Thuille, Mathias Müller, Lukas Roth, Andreas Katopodis, Gottfried Baier
J Autoimmun. 2012 Dec; 39(4): 428–440. doi: 10.1016/j.jaut.2012.07.007
PMCID:
PMC3516707
AbstractArticle
19.
Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6
Eric T. Weatherford, Xuebo Liu, Curt D. Sigmund
Am J Physiol Renal Physiol. 2012 Apr 15; 302(8): F1025–F1033. Published online 2012 Jan 25. doi: 10.1152/ajprenal.00362.2011
PMCID:
PMC3330716
AbstractArticle
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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