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Items: 1 to 20 of 110

1.
The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
Dae Jin Jeong, Jee-Hyun Um, Young Yeon Kim, Dong Jin Shin, Sangwoo Im, Kang-Min Lee, Yun-Hee Lee, Dae-sik Lim, Donghoon Kim, Jeanho Yun
Exp Mol Med. 2024 Mar; 56(3): 674–685. Published online 2024 Mar 5. doi: 10.1038/s12276-024-01198-y
PMCID:
PMC10984967
AbstractArticlePDF–4.8M
2.
Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions
Yana Xu, Meiyu Qu, Yangxun He, Qiangqiang He, Tingyu Shen, Jiahao Luo, Dan Tan, Hangyang Bao, Chengyun Xu, Xing Ji, Xinhua Hu, Muhammad Qasim Barkat, Ling-Hui Zeng, Ximei Wu
J Biol Chem. 2023 Dec; 299(12): 105395. Published online 2023 Oct 27. doi: 10.1016/j.jbc.2023.105395
PMCID:
PMC10696403
AbstractArticlePDF–5.4M
3.
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression
Yan Sun, Xin Jin, Junpeng Meng, Feng Guo, Taoyu Chen, Xiaoyan Zhao, Heshui Wu, Dianyun Ren
EMBO J. 2023 Dec; 42(23): e114558. Published online 2023 Oct 31. doi: 10.15252/embj.2023114558
PMCID:
PMC10690468
AbstractArticlePDF–17M
4.
The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregation
Yilin Wang, Patrik Risteski, Yang Yang, Huan Chen, Gaith Droby, Andrea Walens, Deepika Jayaprakash, Melissa Troester, Laura Herring, Jonathan Chernoff, Iva M Tolić, Jessica Bowser, Cyrus Vaziri
Nucleic Acids Res. 2023 Oct 27; 51(19): 10568–10589. Published online 2023 Sep 22. doi: 10.1093/nar/gkad766
PMCID:
PMC10602929
AbstractArticlePDF–2.9M
5.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
AbstractArticlePDF–2.4M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
8.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
9.
Extracellular matrix stiffness regulates degradation of MST2 via SCF βTrCP
Ana Paula Zen Petisco Fiore, Ana Maria Rodrigues, Helder Veras Ribeiro-Filho, Antonio Carlos Manucci, Pedro de Freitas Ribeiro, Mayara Carolinne Silva Botelho, Christine Vogel, Paulo Sergio Lopes-de-Oliveira, Michele Pagano, Alexandre Bruni-Cardoso
Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2022 Dec; 1866(12): 130238. Published online 2022 Aug 28. doi: 10.1016/j.bbagen.2022.130238
PMCID:
PMC9926743
AbstractArticlePDF–1.0M
10.
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway
Shili Ning, Yuzhuo Chen, Guangzhi Wang, Yongtai Liu, Yingchi Yang, Zhongtao Zhang
Front Oncol. 2022; 12: 1031160. Published online 2022 Dec 29. doi: 10.3389/fonc.2022.1031160
PMCID:
PMC9837830
AbstractArticlePDF–26M
11.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
12.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
13.
Regulation of MST complexes and activity via SARAH domain modifications
Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff
Biochem Soc Trans. Author manuscript; available in PMC 2022 Oct 7.
Published in final edited form as: Biochem Soc Trans. 2021 Apr 30; 49(2): 675–683. doi: 10.1042/BST20200559
PMCID:
PMC9540434
AbstractArticlePDF–485K
14.
FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ
Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li
Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831
PMCID:
PMC9491713
AbstractArticlePDF–12M
15.
Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma
David Romano, Lucía García-Gutiérrez, Nourhan Aboud, David J Duffy, Keith T Flaherty, Dennie T Frederick, Walter Kolch, David Matallanas
Life Sci Alliance. 2022 Oct; 5(10): e202201445. Published online 2022 Aug 29. doi: 10.26508/lsa.202201445
PMCID:
PMC9434705
AbstractArticlePDF–2.0M
16.
Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner
Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas
Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3
PMCID:
PMC9360443
AbstractArticlePDF–5.8M
17.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
18.
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis
Nat Commun. 2022; 13: 3181. Published online 2022 Jun 8. doi: 10.1038/s41467-022-30794-7
PMCID:
PMC9177965
AbstractArticlePDF–2.2M
19.
Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway
Christina Priest, Rohith T. Nagari, Lara Bideyan, Stephen D. Lee, Alexander Nguyen, Xu Xiao, Peter Tontonoz
Proc Natl Acad Sci U S A. 2022 May 3; 119(18): e2201859119. Published online 2022 Apr 27. doi: 10.1073/pnas.2201859119
PMCID:
PMC9171358
AbstractArticlePDF–3.1M
20.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M

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