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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105503213.

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress

Sonia Vidushi Gupta, Lillian Campos, Kristina Hildegard Schmidt

Genetics. 2023 Oct; 225(2): iyad147. Published online 2023 Aug 29. doi: 10.1093/genetics/iyad147

PMCID:: PMC10550321

Abstract Article PDF–1.2M

Select item 102977004.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102333685.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 96309866.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 87598218.

The Zn-finger of Saccharomyces cerevisiae Rad18 and its adjacent region mediate interaction with Rad5

Orsolya Frittmann, Vamsi K Gali, Miklos Halmai, Robert Toth, Zsuzsanna Gyorfy, Eva Balint, Ildiko Unk

G3 (Bethesda) 2021 Apr; 11(4): jkab041. Published online 2021 Feb 11. doi: 10.1093/g3journal/jkab041

PMCID:: PMC8759821

Abstract Article PDF–895K

Select item 85890329.

Structures of REV1 UBM2 domain complex with ubiquitin and with a small-molecule that inhibits the REV1 UBM2-ubiquitin interaction

Murugendra Vanarotti, Christy R. Grace, Darcie J. Miller, Marcelo L. Actis, Akira Inoue, Benjamin J. Evison, Sivaraja Vaithiyalingam, Aman P. Singh, Ezelle T. McDonald, Naoaki Fujii

J Mol Biol. Author manuscript; available in PMC 2021 Nov 12.

Published in final edited form as: J Mol Biol. 2018 Aug 17; 430(17): 2857–2872. Published online 2018 Jun 2. doi: 10.1016/j.jmb.2018.05.042

PMCID:: PMC8589032

Abstract Article PDF–2.2M

Select item 831953110.

Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ

Chloe Du Truong, Theodore A. Craig, Gaofeng Cui, Maria Victoria Botuyan, Rachel A. Serkasevich, Ka-Yi Chan, Georges Mer, Po-Lin Chiu, Rajiv Kumar

J Biol Chem. 2021 Aug; 297(2): 100912. Published online 2021 Jun 24. doi: 10.1016/j.jbc.2021.100912

PMCID:: PMC8319531

Abstract Article PDF–2.1M

Select item 824047311.

Yeast DNA polymerase η possesses two PIP-like motifs that bind PCNA and Rad6-Rad18 with different specificities

Brittany M. Ripley, Devin T. Reusch, M. Todd Washington

DNA Repair (Amst) Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2020 Nov; 95: 102968. Published online 2020 Sep 6. doi: 10.1016/j.dnarep.2020.102968

PMCID:: PMC8240473

Abstract Article PDF–869K

Select item 801257312.

Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism

Ruofan Yu, Xiaohua Cao, Luyang Sun, Jun-yi Zhu, Brian M Wasko, Wei Liu, Emeline Crutcher, Haiying Liu, Myeong Chan Jo, Lidong Qin, Matt Kaeberlein, Zhe Han, Weiwei Dang

Nat Commun. 2021; 12: 1981. Published online 2021 Mar 31. doi: 10.1038/s41467-021-22257-2

PMCID:: PMC8012573

Abstract Article PDF–3.1M

Select item 791754913.

The eukaryotic replisome tolerates leading‐strand base damage by replicase switching

Thomas A Guilliam, Joseph TP Yeeles

EMBO J. 2021 Mar 1; 40(5): e107037. Published online 2021 Feb 8. doi: 10.15252/embj.2020107037

PMCID:: PMC7917549

Abstract Article PDF–1.7M

Select item 789130214.

Regulation of UV damage repair in quiescent yeast cells

Lindsey J. Long, Po-Hsuen Lee, Eric M. Small, Cory Hillyer, Yan Guo, Mary Ann Osley

DNA Repair (Amst) Author manuscript; available in PMC 2021 Feb 18.

Published in final edited form as: DNA Repair (Amst). 2020 Jun; 90: 102861. Published online 2020 Apr 30. doi: 10.1016/j.dnarep.2020.102861

PMCID:: PMC7891302

Abstract Article PDF–1018K

Select item 786153115.

Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair

Natasha C. Koussa, Duncan J. Smith

PLoS Genet. 2021 Jan; 17(1): e1009322. Published online 2021 Jan 25. doi: 10.1371/journal.pgen.1009322

PMCID:: PMC7861531

Abstract Article PDF–1.9M

Select item 778845916.

Non‐recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance

María I Cano‐Linares, Aurora Yáñez‐Vilches, Néstor García‐Rodríguez, Marta Barrientos‐Moreno, Román González‐Prieto, Pedro San‐Segundo, Helle D Ulrich, Félix Prado

EMBO Rep. 2021 Jan 7; 22(1): e50410. Published online 2020 Dec 2. doi: 10.15252/embr.202050410

PMCID:: PMC7788459

Abstract Article PDF–2.2M

Select item 756831017.

Visualizing Rev1 catalyze protein-template DNA synthesis

Tyler M. Weaver, Luis M. Cortez, Thu H. Khoang, M. Todd Washington, Pratul K. Agarwal, Bret D. Freudenthal

Proc Natl Acad Sci U S A. 2020 Oct 13; 117(41): 25494–25504. Published online 2020 Sep 30. doi: 10.1073/pnas.2010484117

PMCID:: PMC7568310

Abstract Article PDF–1.9M

Select item 754721118.

Trajectory and uniqueness of mutational signatures in yeast mutators

Sophie Loeillet, Mareike Herzog, Fabio Puddu, Patricia Legoix, Sylvain Baulande, Stephen P. Jackson, Alain G. Nicolas

Proc Natl Acad Sci U S A. 2020 Oct 6; 117(40): 24947–24956. Published online 2020 Sep 23. doi: 10.1073/pnas.2011332117

PMCID:: PMC7547211

Abstract Article PDF–1.8M

Select item 750254519.

Genetic characterization of three distinct mechanisms supporting RNA-driven DNA repair and modification reveals major role of DNA polymerase ζ

Chance Meers, Havva Keskin, Gabor Banyai, Olga Mazina, Taehwan Yang, Alli L. Gombolay, Kuntal Mukherjee, Efiyenia I. Kaparos, Gary Newnam, Alexander Mazin, Francesca Storici

Mol Cell. Author manuscript; available in PMC 2021 Sep 17.

Published in final edited form as: Mol Cell. 2020 Sep 17; 79(6): 1037–1050.e5. Published online 2020 Sep 2. doi: 10.1016/j.molcel.2020.08.011