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Select item 111510921.

Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion

Amy Orr, William Wickner

Mol Biol Cell. 2024 May 1; 35(5): ar71. Published online 2024 Apr 16. doi: 10.1091/mbc.E24-02-0060

PMCID:: PMC11151092

Abstract Article PDF–2.6M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98363484.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 86939726.

Phosphatidylinositol and phosphatidylinositol-3-phosphate activate HOPS to catalyze SNARE assembly, allowing small headgroup lipids to support the terminal steps of membrane fusion

Thomas Torng, William Wickner

Mol Biol Cell. 2021 Nov 1; 32(21): ar19. doi: 10.1091/mbc.E21-07-0373

PMCID:: PMC8693972

Abstract Article PDF–4.2M

Select item 85915117.

Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi

Jannis Schoppe, Evelyn Schubert, Amir Apelbaum, Erdal Yavavli, Oliver Birkholz, Heike Stephanowitz, Yaping Han, Angela Perz, Oliver Hofnagel, Fan Liu, Jacob Piehler, Stefan Raunser, Christian Ungermann

J Biol Chem. 2021 Nov; 297(5): 101334. Published online 2021 Oct 22. doi: 10.1016/j.jbc.2021.101334

PMCID:: PMC8591511

Abstract Article PDF–4.7M

Select item 85769178.

Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis

Emmanuel T. Nsamba, Abesh Bera, Michael Costanzo, Charles Boone, Mohan L. Gupta, Jr.

J Cell Biol. 2021 Dec 6; 220(12): e202010155. Published online 2021 Nov 5. doi: 10.1083/jcb.202010155

PMCID:: PMC8576917

Abstract Article PDF–7.4M

Select item 83866289.

PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes

Hongjun Zhang, Jiao Zhou, Peng Xiao, Yong Lin, Xin Gong, Shiyan Liu, Qingjia Xu, Minjin Wang, Haiyan Ren, Mengji Lu, Yuan Wang, Jing Zhu, Zhiping Xie, Huihui Li, Kefeng Lu

Autophagy. 2021; 17(8): 1907–1917. Published online 2020 Jul 30. doi: 10.1080/15548627.2020.1796321

PMCID:: PMC8386628

Abstract Article PDF–8.5M

Select item 825961310.

Genetically encoded multimode reporter of adaptor protein 3 (AP-3) traffic in budding yeast

Rachael L. Plemel, Greg Odorizzi, Alexey J. Merz

Traffic. Author manuscript; available in PMC 2021 Jul 6.

Published in final edited form as: Traffic. 2021 Jan; 22(1-2): 38–44. Published online 2020 Dec 7. doi: 10.1111/tra.12772

PMCID:: PMC8259613

Abstract Article PDF–1.8M

Select item 772681511.

Atg1 kinase regulates autophagosome‐vacuole fusion by controlling SNARE bundling

Saskia Barz, Franziska Kriegenburg, Anna Henning, Anuradha Bhattacharya, Hector Mancilla, Pablo Sánchez‐Martín, Claudine Kraft

EMBO Rep. 2020 Dec 3; 21(12): e51869. Published online 2020 Dec 3. doi: 10.15252/embr.202051869

PMCID:: PMC7726815

Abstract Article PDF–3.6M

Select item 772147512.

A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits

Florian Wilfling, Chia-Wei Lee, Philipp S. Erdmann, Yumei Zheng, Dawafuti Sherpa, Stefan Jentsch, Boris Pfander, Brenda A. Schulman, Wolfgang Baumeister

Mol Cell. 2020 Dec 3; 80(5): 764–778.e7. doi: 10.1016/j.molcel.2020.10.030

PMCID:: PMC7721475

Abstract Article

Select item 771875113.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 744969914.

Complementary α-arrestin-ubiquitin ligase complexes control nutrient transporter endocytosis in response to amino acids

Vasyl Ivashov, Johannes Zimmer, Sinead Schwabl, Jennifer Kahlhofer, Sabine Weys, Ronald Gstir, Thomas Jakschitz, Leopold Kremser, Günther K Bonn, Herbert Lindner, Lukas A Huber, Sebastien Leon, Oliver Schmidt, David Teis

eLife. 2020; 9: e58246. Published online 2020 Aug 3. doi: 10.7554/eLife.58246

PMCID:: PMC7449699

Abstract Article PDF–3.9M

Select item 732543515.

A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae

Su Ming Sun, Amandine Batté, Mireille Elmer, Sophie C. van der Horst, Tibor van Welsem, Gordon Bean, Trey Ideker, Fred van Leeuwen, Haico van Attikum

J Cell Sci. 2020 May 15; 133(10): jcs237628. Published online 2020 May 22. doi: 10.1242/jcs.237628

PMCID:: PMC7325435

Abstract Article

Select item 680078516.

Copper blocks V-ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion

Gregory E. Miner, Katherine D. Sullivan, Chi Zhang, Logan R. Hurst, Matthew L. Starr, David A. Rivera-Kohr, Brandon C. Jones, Annie Guo, Rutilio A. Fratti

Traffic. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Traffic. 2019 Nov; 20(11): 841–850. Published online 2019 Sep 2. doi: 10.1111/tra.12683

PMCID:: PMC6800785

Abstract Article PDF–1.2M

Select item 662879117.

Tethering guides fusion-competent trans-SNARE assembly

Hongki Song, William Wickner

Proc Natl Acad Sci U S A. 2019 Jul 9; 116(28): 13952–13957. Published online 2019 Jun 24. doi: 10.1073/pnas.1907640116

PMCID:: PMC6628791

Abstract Article PDF–1.2M

Select item 634722918.

Rab5-independent activation and function of yeast Rab7-like protein, Ypt7p, in the AP-3 pathway

Hiroki Shimamura, Makoto Nagano, Keita Nakajima, Junko Y. Toshima, Jiro Toshima

PLoS One. 2019; 14(1): e0210223. Published online 2019 Jan 25. doi: 10.1371/journal.pone.0210223

PMCID:: PMC6347229

Abstract Article PDF–3.4M

Select item 624980219.

Lipid trafficking by yeast Snx4 family SNX-BAR proteins promotes autophagy and vacuole membrane fusion

Mengxiao Ma, Santosh Kumar, Latha Purushothaman, Markus Babst, Christian Ungermann, Richard J. Chi, Christopher G. Burd

Mol Biol Cell. 2018 Sep 1; 29(18): 2190–2200. doi: 10.1091/mbc.E17-12-0743

PMCID:: PMC6249802

Abstract Article PDF–1.8M

Select item 621571320.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

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