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Items: 1 to 20 of 68

1.
Structural basis of frizzled 7 activation and allosteric regulation
Julien Bous, Julia Kinsolving, Lukas Grätz, Magdalena M. Scharf, Jan Hendrik Voss, Berkay Selcuk, Ogün Adebali, Gunnar Schulte
Nat Commun. 2024; 15: 7422. Published online 2024 Aug 28. doi: 10.1038/s41467-024-51664-4
PMCID:
PMC11358414
AbstractArticlePDF–2.5M
2.
HAS2 facilitates glioma cell malignancy and suppresses ferroptosis in an FZD7‐dependent manner
Zhiyuan Liu, Kuo Yu, Kaile Chen, Jinlai Liu, Kexiang Dai, Peng Zhao
Cancer Sci. 2024 Aug; 115(8): 2602–2616. Published online 2024 May 30. doi: 10.1111/cas.16232
PMCID:
PMC11309948
AbstractArticlePDF–43M
3.
MiR-1-3p通过靶向FZD7增强卵巢癌细胞对铁死亡的敏感性
章 迪, 屈 斌, 胡 彬, 曹 可欣, 沈 浩明
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Nov 28; 47(11): 1512–1521. Chinese. doi: 10.11817/j.issn.1672-7347.2022.210800
PMCID:
PMC10930623
AbstractArticlePDF–1.9M
4.
WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling
Qingling Huang, Yi Xiao, Ting Lan, Youguang Lu, Li Huang, Dali Zheng
Int J Oral Sci. 2024; 16: 7. Published online 2024 Jan 22. doi: 10.1038/s41368-024-00279-y
PMCID:
PMC10800352
AbstractArticlePDF–4.2M
5.
FZD7: A potential biomarker for endometriosis
Suwei Lan, Zhengmao Zhang, Qing Li
Medicine (Baltimore) 2023 Oct 6; 102(40): e35406. Published online 2023 Oct 6. doi: 10.1097/MD.0000000000035406
PMCID:
PMC10553041
AbstractArticlePDF–871K
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
FZD7 accelerates hepatic metastases in pancreatic cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling
Zhongbo Zhang, Yuanhong Xu
Mol Med. 2022; 28: 82. Published online 2022 Jul 19. doi: 10.1186/s10020-022-00509-1
PMCID:
PMC9295360
AbstractArticlePDF–2.2M
8.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
9.
Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters
Ernest Palomer, Núria Martín-Flores, Sarah Jolly, Patricia Pascual-Vargas, Stefano Benvegnù, Marina Podpolny, Samuel Teo, Kadi Vaher, Takashi Saito, Takaomi C. Saido, Paul Whiting, Patricia C. Salinas
Mol Psychiatry. 2022; 27(7): 3024–3033. Published online 2022 Mar 16. doi: 10.1038/s41380-022-01492-z
PMCID:
PMC9205772
AbstractArticlePDF–2.6M
10.
GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling
Liang Wang, Jiayi Wang, Xiaolin Yin, Xin Guan, Ying Li, Chenqi Xin, Jing Liu
Oncogene. 2022; 41(18): 2609–2623. Published online 2022 Mar 28. doi: 10.1038/s41388-022-02255-4
PMCID:
PMC9054671
AbstractArticlePDF–6.7M
11.
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs
Katherine M. Almasy, Jonathan P. Davies, Lars Plate
Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120
PMCID:
PMC8236078
AbstractArticlePDF–4.6M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer
Zhongbo Zhang, Yuanhong Xu, Chenghai Zhao
Cancer Med. 2021 May; 10(10): 3332–3345. Published online 2021 May 2. doi: 10.1002/cam4.3819
PMCID:
PMC8124113
AbstractArticlePDF–2.5M
14.
Frizzled-7 identifies platinum-tolerant ovarian cancer cells susceptible to ferroptosis
Yinu Wang, Guangyuan Zhao, Salvatore Condello, Hao Huang, Horacio Cardenas, Edward J. Tanner, JianJun Wei, Yanrong Ji, Junjie Li, Yuying Tan, Ramana V. Davuluri, Marcus E. Peter, Ji-Xin Cheng, Daniela Matei
Cancer Res. Author manuscript; available in PMC 2021 Jul 15.
Published in final edited form as: Cancer Res. 2021 Jan 15; 81(2): 384–399. Published online 2020 Nov 10. doi: 10.1158/0008-5472.CAN-20-1488
PMCID:
PMC7855035
AbstractArticlePDF–2.8M
15.
A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway
Wei Xie, Huijie Zhao, Fengxian Wang, Yiyun Wang, Yuan He, Tong Wang, Kunchi Zhang, Hao Yang, Zhaoli Zhou, Haibin Shi, Jin Wang, Gang Huang
J Exp Clin Cancer Res. 2021; 40: 30. Published online 2021 Jan 12. doi: 10.1186/s13046-020-01800-x
PMCID:
PMC7802198
AbstractArticlePDF–4.1M
16.
Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells
Diana Gumber, Myan Do, Neya Suresh Kumar, Pooja R Sonavane, Christina C N Wu, Luisjesus S Cruz, Stephanie Grainger, Dennis Carson, Terry Gaasterland, Karl Willert
eLife. 2020; 9: e63060. Published online 2020 Dec 17. doi: 10.7554/eLife.63060
PMCID:
PMC7759383
AbstractArticlePDF–4.6M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Expression of LGR5, FZD7, TROY, and MIST1 in Perioperatively Treated Gastric Carcinomas and Correlation with Therapy Response
Antonia Freiin Grote, Christine Halske, Hans-Michael Behrens, Sandra Krüger, Franziska Wilhelm, Jan-Hendrik Egberts, Christoph Röcken
Dis Markers. 2019; 2019: 8154926. Published online 2019 Nov 19. doi: 10.1155/2019/8154926
PMCID:
PMC6885822
AbstractArticlePDF–3.1M
19.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
20.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt–β-catenin pathway
Qiang Liu, Yanlei Guan, Zhenhang Li, Yao Wang, Yu Liu, Run Cui, Yunjie Wang
J Exp Clin Cancer Res. 2019; 38: 358. Published online 2019 Aug 16. doi: 10.1186/s13046-019-1370-1
PMCID:
PMC6697940
AbstractArticlePDF–8.8M

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