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Select item 111478521.

NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom severity through neuroanatomical changes in schizophrenia

Carmen Almodóvar-Payá, Maria Guardiola-Ripoll, Maria Giralt-López, Maitane Oscoz-Irurozqui, Erick Jorge Canales-Rodríguez, Mercè Madre, Joan Soler-Vidal, Núria Ramiro, Luis F. Callado, Bárbara Arias, Carme Gallego, Edith Pomarol-Clotet, Mar Fatjó-Vilas

Brain Struct Funct. 2024; 229(5): 1299–1315. Published online 2024 May 9. doi: 10.1007/s00429-024-02793-5

PMCID:: PMC11147852

Abstract Article PDF–1.8M

Select item 110712572.

NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma

Lucia Devitt, Dana Westphal, Katharina Pieger, Nadja Schneider, Anja Katrin Bosserhoff, Silke Kuphal

Cell Commun Signal. 2024; 22: 256. Published online 2024 May 6. doi: 10.1186/s12964-024-01632-8

PMCID:: PMC11071257

Abstract Article PDF–1.9M

Select item 105774523.

Neuritin affects the activity of neuralized-like 1 by promoting degradation and weakening its affinity for substrate: Neuritin regulates the activity of the E3 ligase NEURL1

Jingling Zhu, Yu Li, Chen Zhong, Meiyi Zhu, Yan Zheng, Anying Xiong, Pingping Meng, Liya Shan, Yang Li, Jin Huang

Acta Biochim Biophys Sin (Shanghai) 2023 Oct 25; 55(10): 1650–1658. Published online 2023 May 29. doi: 10.3724/abbs.2023098

PMCID:: PMC10577452

Abstract Article PDF–1.8M

Select item 102333034.

Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease

Cheyenne Hurst, Derian A. Pugh, Measho H. Abreha, Duc M. Duong, Eric B. Dammer, David A. Bennett, Jeremy H. Herskowitz, Nicholas T. Seyfried

Mol Cell Proteomics. 2023 May; 22(5): 100542. Published online 2023 Apr 5. doi: 10.1016/j.mcpro.2023.100542

PMCID:: PMC10233303

Abstract Article PDF–4.1M

Select item 95787075.

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia

eLife. 2022; 11: e81398. Published online 2022 Sep 30. doi: 10.7554/eLife.81398

PMCID:: PMC9578707

Abstract Article PDF–3.3M

Select item 92676326.

NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches

Carmen Almodóvar-Payá, Maria Guardiola-Ripoll, Maria Giralt-López, Carme Gallego, Pilar Salgado-Pineda, Salvador Miret, Raymond Salvador, María J. Muñoz, Luisa Lázaro, Amalia Guerrero-Pedraza, Mara Parellada, María I. Carrión, Manuel J. Cuesta, Teresa Maristany, Salvador Sarró, Lourdes Fañanás, Luis F. Callado, Bárbara Arias, Edith Pomarol-Clotet, Mar Fatjó-Vilas

Int J Mol Sci. 2022 Jul; 23(13): 7456. Published online 2022 Jul 5. doi: 10.3390/ijms23137456

PMCID:: PMC9267632

Abstract Article PDF–1.0M

Select item 82532877.

Methylation of NRN1 is a novel synthetic lethal marker of PI3K‐Akt‐mTOR and ATR inhibitors in esophageal cancer

Wushuang Du, Aiai Gao, James G. Herman, Lidong Wang, Lirong Zhang, Shunchang Jiao, Mingzhou Guo

Cancer Sci. 2021 Jul; 112(7): 2870–2883. Published online 2021 May 16. doi: 10.1111/cas.14917

PMCID:: PMC8253287

Abstract Article PDF–2.2M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67708699.

Decreased Level of Neurotrophic Factor Neuritin 1 in Women with Ovarian Endometriosis after Receiving Gonadotropin-Releasing Hormone Agonist Treatment

Endah Rahmawati, Wei-Chung Vivian Yang, Yen-Ping Lei, Pawan Kumar Maurya, Huei-Wen Chen, Chii-Ruey Tzeng

Int J Mol Sci. 2019 Sep; 20(18): 4352. Published online 2019 Sep 5. doi: 10.3390/ijms20184352

PMCID:: PMC6770869

Abstract Article PDF–3.8M

Select item 623776310.

High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs

Eric W Ottesen, Natalia N Singh, Diou Luo, Ravindra N Singh

Nucleic Acids Res. 2018 Nov 16; 46(20): 10983–11001. Published online 2018 Aug 27. doi: 10.1093/nar/gky770

PMCID:: PMC6237763

Abstract Article PDF–7.4M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535204012.

The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry

Anja Katrin Bosserhoff, Nadja Schneider, Lisa Ellmann, Lucie Heinzerling, Silke Kuphal

Oncotarget. 2017 Jan 3; 8(1): 1117–1131. Published online 2016 Nov 25. doi: 10.18632/oncotarget.13585

PMCID:: PMC5352040

Abstract Article PDF–9.5M

Select item 501613413.

Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway

Jin-jing Yao, Qian-Ru Zhao, Dong-Dong Liu, Chi-Wing Chow, Yan-Ai Mei

J Biol Chem. 2016 Aug 12; 291(33): 17369–17381. Published online 2016 Jun 15. doi: 10.1074/jbc.M115.708883

PMCID:: PMC5016134

Abstract Article PDF–2.9M

Select item 412517914.

Neuritin Attenuates Cognitive Function Impairments in Tg2576 Mouse Model of Alzheimer's Disease

Yoori Choi, Kihwan Lee, Junghwa Ryu, Hyoun Geun Kim, A Young Jeong, Ran-Sook Woo, Jun-Ho Lee, Jin Won Hyun, Seokyung Hahn, Joung-Hun Kim, Hye-Sun Kim

PLoS One. 2014; 9(8): e104121. Published online 2014 Aug 7. doi: 10.1371/journal.pone.0104121

PMCID:: PMC4125179

Abstract Article PDF–4.0M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312185816.

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits

Bikem Akten, Min Jeong Kye, Le T. Hao, Mary H. Wertz, Sasha Singh, Duyu Nie, Jia Huang, Tanuja T. Merianda, Jeffery L. Twiss, Christine E. Beattie, Judith A. J. Steen, Mustafa Sahin

Proc Natl Acad Sci U S A. 2011 Jun 21; 108(25): 10337–10342. Published online 2011 Jun 7. doi: 10.1073/pnas.1104928108

PMCID:: PMC3121858

Abstract Article PDF–718K

Select item 282806017.

cpg15 and cpg15-2 Constitute a Family of Activity-Regulated Ligands Expressed Differentially in the Nervous System to Promote Neurite Growth and Neuronal Survival

TADAHIRO FUJINO, ZHEN WU, WALTER C. LIN, MARNIE A. PHILLIPS, ELLY NEDIVI

J Comp Neurol. Author manuscript; available in PMC 2010 Feb 24.

Published in final edited form as: J Comp Neurol. 2008 Apr 10; 507(5): 1831–1845. doi: 10.1002/cne.21649

PMCID:: PMC2828060

Abstract Article PDF–2.6M

Select item 135612918.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892819.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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