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Select item 87690721.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79535923.

The E3 ligases Spsb1 and Spsb4 regulate RevErbα degradation and circadian period.

Tsedey Mekbib, Ting-Chung Suen, Aisha Rollins-Hairston, Jason P. DeBruyne

J Biol Rhythms. Author manuscript; available in PMC 2021 Mar 12.

Published in final edited form as: J Biol Rhythms. 2019 Dec; 34(6): 610–621. Published online 2019 Oct 14. doi: 10.1177/0748730419878036

PMCID:: PMC7953592

Abstract Article PDF–1.1M

Select item 73114674.

SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites

Liwen Zhou, Lisi Zheng, Kaishun Hu, Xin Wang, Ruhua Zhang, Yezi Zou, Li Zhong, Shang Wang, Yuanzhong Wu, Tiebang Kang

Signal Transduct Target Ther. 2020; 5: 80. Published online 2020 Jun 24. doi: 10.1038/s41392-020-0172-4

PMCID:: PMC7311467

Abstract Article PDF–3.9M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71536956.

ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection

Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan

Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.

Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008

PMCID:: PMC7153695

Abstract Article PDF–2.6M

Select item 69853657.

Cullin-5 Adaptor SPSB1 Controls NF-κB Activation Downstream of Multiple Signaling Pathways

Iliana Georgana, Carlos Maluquer de Motes

Front Immunol. 2019; 10: 3121. Published online 2020 Jan 21. doi: 10.3389/fimmu.2019.03121

PMCID:: PMC6985365

Abstract Article PDF–5.2M

Select item 58509168.

Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1

Sheng Liu, Josephine Iaria, Richard J. Simpson, Hong-Jian Zhu

Cell Commun Signal. 2018; 16: 10. Published online 2018 Mar 13. doi: 10.1186/s12964-018-0223-4

PMCID:: PMC5850916

Abstract Article PDF–3.8M

Select item 56837639.

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2

Fumihiko Okumura, Akiko Joo-Okumura, Keisuke Obara, Alexander Petersen, Akihiko Nishikimi, Yoshinori Fukui, Kunio Nakatsukasa, Takumi Kamura

Mol Biol Cell. 2017 Nov 15; 28(24): 3532–3541. doi: 10.1091/mbc.E17-07-0450

PMCID:: PMC5683763

Abstract Article PDF–2.5M

Select item 549522510.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 538562111.

SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling

Feng Wang, Xing Fu, Peng Chen, Ping Wu, Xiaojuan Fan, Na Li, Hong Zhu, Ting-Ting Jia, Hongbin Ji, Zefeng Wang, Catherine C L Wong, Ronggui Hu, Jingyi Hui

Cell Res. 2017 Apr; 27(4): 540–558. Published online 2017 Jan 13. doi: 10.1038/cr.2017.7

PMCID:: PMC5385621

Abstract Article PDF–7.4M

Select item 464794112.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 450503813.

SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor

Sheng Liu, Thao Nheu, Rodney Luwor, Sandra E. Nicholson, Hong-Jian Zhu

J Biol Chem. 2015 Jul 17; 290(29): 17894–17908. Published online 2015 Jun 1. doi: 10.1074/jbc.M114.607184

PMCID:: PMC4505038

Abstract Article PDF–2.4M

Select item 444642914.

RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling

Ananya Kar, Manpreet Kaur, Tanushree Ghosh, Md. Muntaz Khan, Aparna Sharma, Ritu Shekhar, Akhil Varshney, Sandeep Saxena

Nucleic Acids Res. 2015 May 26; 43(10): 4962–4974. Published online 2015 Apr 27. doi: 10.1093/nar/gkv369

PMCID:: PMC4446429

Abstract Article PDF–9.4M

Select item 415962215.

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis

Hanqiu Zheng, Minhong Shen, Yin-Lian Cha, Wenyang Li, Yong Wei, Mario Andres Blanco, Guangwen Ren, Tianhua Zhou, Peter Storz, Hui-Yun Wang, Yibin Kang

Cancer Cell. Author manuscript; available in PMC 2015 Sep 8.

Published in final edited form as: Cancer Cell. 2014 Sep 8; 26(3): 358–373. doi: 10.1016/j.ccr.2014.07.022