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Items: 12

1.
Structural basis of cytokine-mediated activation of ALK family receptors
Steven De Munck, Mathias Provost, Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Felix, Yehudi Bloch, Omar Abdel-Wahab, J. Fernando Bazan, Akihide Yoshimi, Savvas N. Savvides
Nature. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Nature. 2021 Dec; 600(7887): 143–147. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03959-5
PMCID:
PMC9343967
AbstractArticlePDF–7.8M
2.
The autocrine loop of ALK receptor and ALKAL2 ligand is an actionable target in consensus molecular subtype 1 colon cancer
Martina Mazzeschi, Michela Sgarzi, Donatella Romaniello, Valerio Gelfo, Carola Cavallo, Francesca Ambrosi, Alessandra Morselli, Carmen Miano, Noemi Laprovitera, Cinzia Girone, Manuela Ferracin, Spartaco Santi, Karim Rihawi, Andrea Ardizzoni, Michelangelo Fiorentino, Gabriele D’Uva, Balázs Győrffy, Ruth Palmer, Mattia Lauriola
J Exp Clin Cancer Res. 2022; 41: 113. Published online 2022 Mar 29. doi: 10.1186/s13046-022-02309-1
PMCID:
PMC8962179
AbstractArticlePDF–8.7M
3.
Mechanism for the activation of the anaplastic lymphoma kinase receptor
Andrey V. Reshetnyak, Paolo Rossi, Alexander G. Myasnikov, Munia Sowaileh, Jyotidarsini Mohanty, Amanda Nourse, Darcie J. Miller, Irit Lax, Joseph Schlessinger, Charalampos G. Kalodimos
Nature. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: Nature. 2021 Dec; 600(7887): 153–157. Published online 2021 Nov 24. doi: 10.1038/s41586-021-04140-8
PMCID:
PMC8639797
AbstractArticlePDF–4.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation
Marcus Borenäs, Ganesh Umapathy, Wei‐Yun Lai, Dan E Lind, Barbara Witek, Jikui Guan, Patricia Mendoza‐Garcia, Tafheem Masudi, Arne Claeys, Tzu‐Po Chuang, Abeer El Wakil, Badrul Arefin, Susanne Fransson, Jan Koster, Mathias Johansson, Jennie Gaarder, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
EMBO J. 2021 Feb 1; 40(3): e105784. Published online 2021 Jan 7. doi: 10.15252/embj.2020105784
PMCID:
PMC7849294
AbstractArticlePDF–3.1M
6.
Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α)
Andrey V. Reshetnyak, Jyotidarsini Mohanty, Francisco Tomé, David E. Puleo, Alexander N. Plotnikov, Mansoor Ahmed, Navjot Kaur, Anton Poliakov, Arul M. Cinnaiyan, Irit Lax, Joseph Schlessinger
Proc Natl Acad Sci U S A. 2018 Aug 14; 115(33): 8340–8345. Published online 2018 Jul 30. doi: 10.1073/pnas.1807881115
PMCID:
PMC6099872
AbstractArticlePDF–975K
7.
ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells
Andrey Fadeev, Patricia Mendoza-Garcia, Uwe Irion, Jikui Guan, Kathrin Pfeifer, Stephanie Wiessner, Fabrizio Serluca, Ajeet Pratap Singh, Christiane Nüsslein-Volhard, Ruth H. Palmer
Proc Natl Acad Sci U S A. 2018 Jan 23; 115(4): E630–E638. Published online 2018 Jan 9. doi: 10.1073/pnas.1719137115
PMCID:
PMC5789956
AbstractArticlePDF–2.1M
8.
Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand–receptor interactions
Andrey V. Reshetnyak, Phillip B. Murray, Xiarong Shi, Elizabeth S. Mo, Jyotidarsini Mohanty, Francisco Tome, Hanwen Bai, Murat Gunel, Irit Lax, Joseph Schlessinger
Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52): 15862–15867. Published online 2015 Nov 16. doi: 10.1073/pnas.1520099112
PMCID:
PMC4702955
AbstractArticlePDF–1.2M
9.
FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase
Jikui Guan, Ganesh Umapathy, Yasuo Yamazaki, Georg Wolfstetter, Patricia Mendoza, Kathrin Pfeifer, Ateequrrahman Mohammed, Fredrik Hugosson, Hongbing Zhang, Amy W Hsu, Robert Halenbeck, Bengt Hallberg, Ruth H Palmer
eLife. 2015; 4: e09811. Published online 2015 Sep 29. doi: 10.7554/eLife.09811
PMCID:
PMC4658194
AbstractArticlePDF–3.8M
10.
Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome
Hongbing Zhang, Lily I. Pao, Aileen Zhou, Arthur D. Brace, Robert Halenbeck, Amy W. Hsu, Thomas L. Bray, Kevin Hestir, Elizabeth Bosch, Ernestine Lee, Gang Wang, Haixia Liu, Brian R. Wong, W. Michael Kavanaugh, Lewis T. Williams
Proc Natl Acad Sci U S A. 2014 Nov 4; 111(44): 15741–15745. Published online 2014 Oct 20. doi: 10.1073/pnas.1412009111
PMCID:
PMC4226105
AbstractArticlePDF–996K
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment
Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski
Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003
Correction in:
Genome Res. 2003 Dec; 13(12): 2759.
PMCID:
PMC403697
AbstractArticlePDF–120K

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