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Select item 110112021.

Numerous Serine/Threonine Kinases Affect Blood Cell Homeostasis in Drosophila melanogaster

Sebastian Deichsel, Bernd M. Gahr, Helena Mastel, Anette Preiss, Anja C. Nagel

Cells. 2024 Apr; 13(7): 576. Published online 2024 Mar 26. doi: 10.3390/cells13070576

PMCID:: PMC11011202

Abstract Article PDF–5.5M

Select item 109898632.

A transcriptomics-based RNAi screen for regulators of meiosis and early stages of oocyte development in Drosophila melanogaster

Stacie E Hughes, Andrew Price, Salam Briggs, Cynthia Staber, Morgan James, Madelyn Anderson, R Scott Hawley

G3 (Bethesda) 2024 Apr; 14(4): jkae028. Published online 2024 Feb 9. doi: 10.1093/g3journal/jkae028

PMCID:: PMC10989863

Abstract Article PDF–1.3M

Select item 108132063.

Loss of the DYRK1A Protein Kinase Results in the Reduction in Ribosomal Protein Gene Expression, Ribosome Mass and Reduced Translation

Chiara Di Vona, Laura Barba, Roberto Ferrari, Susana de la Luna

Biomolecules. 2024 Jan; 14(1): 31. Published online 2023 Dec 25. doi: 10.3390/biom14010031

PMCID:: PMC10813206

Abstract Article PDF–2.9M

Select item 105296714.

Excess glutamate release triggers subunit-specific homeostatic receptor scaling

Yifu Han, Pragya Goel, Jiawen Chen, Sarah Perry, Nancy Tran, Samantha Nishimura, Manisha Sanjani, Chun Chien, Dion Dickman

Cell Rep. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112775. Published online 2023 Jul 11. doi: 10.1016/j.celrep.2023.112775

PMCID:: PMC10529671

Abstract Article PDF–2.1M

Select item 105237615.

Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

Marina L. Garcia-Vaquero, Marjorie Heim, Barbara Flix, Marcelo Pereira, Lucile Palin, Tânia M. Marques, Francisco R. Pinto, Javier de Las Rivas, Aaron Voigt, Florence Besse, Margarida Gama-Carvalho

BMC Genomics. 2023; 24: 576. Published online 2023 Sep 27. doi: 10.1186/s12864-023-09562-4

PMCID:: PMC10523761

Abstract Article PDF–3.2M

Select item 102402106.

The mitochondrial ribosomal protein mRpL4 regulates Notch signaling

Dongqing Mo, Chenglin Liu, Yao Chen, Xinkai Cheng, Jie Shen, Long Zhao, Junzheng Zhang

EMBO Rep. 2023 Jun; 24(6): e55764. Published online 2023 Apr 3. doi: 10.15252/embr.202255764

PMCID:: PMC10240210

Abstract Article PDF–2.5M

Select item 95082687.

DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity

Bangfu Zhu, Tom Parsons, Christopher Foley, Yeng Shaw, Travis Dunckley, Christopher Hulme, James J. L. Hodge

Sci Rep. 2022; 12: 15847. Published online 2022 Sep 23. doi: 10.1038/s41598-022-19967-y

PMCID:: PMC9508268

Abstract Article PDF–3.6M

Select item 93453158.

DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes

Bangfu Zhu, Tom Parsons, Wenche Stensen, John S. Mjøen Svendsen, Anders Fugelli, James J. L. Hodge

Front Pharmacol. 2022; 13: 881385. Published online 2022 Jul 19. doi: 10.3389/fphar.2022.881385

PMCID:: PMC9345315

Abstract Article PDF–2.3M

Select item 89608069.

Genetic variation of macronutrient tolerance in Drosophila melanogaster

E. Havula, S. Ghazanfar, N. Lamichane, D. Francis, K. Hasygar, Y. Liu, L. A. Alton, J. Johnstone, E. J. Needham, T. Pulpitel, T. Clark, H. N. Niranjan, V. Shang, V. Tong, N. Jiwnani, G. Audia, A. N. Alves, L. Sylow, C. Mirth, G. G. Neely, J. Yang, V. Hietakangas, S. J. Simpson, A. M. Senior

Nat Commun. 2022; 13: 1637. Published online 2022 Mar 28. doi: 10.1038/s41467-022-29183-x

PMCID:: PMC8960806

Abstract Article PDF–3.3M

Select item 866448610.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 866445511.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 849187612.

Minibrain kinase and calcineurin coordinate activity-dependent bulk endocytosis through synaptojanin

Yi-Jheng Peng, Junhua Geng, Ying Wu, Cristian Pinales, Jennifer Langen, Yen-Ching Chang, Christopher Buser, Karen T. Chang

J Cell Biol. 2021 Dec 6; 220(12): e202011028. Published online 2021 Oct 1. doi: 10.1083/jcb.202011028

PMCID:: PMC8491876

Abstract Article PDF–7.6M

Select item 820882413.

All Creatures Great and Small: New Approaches for Understanding Down syndrome Genetics

Anna J. Moyer, Katheleen Gardiner, Roger H. Reeves

Trends Genet. Author manuscript; available in PMC 2021 Jun 16.

Published in final edited form as: Trends Genet. 2021 May; 37(5): 444–459. Published online 2020 Oct 20. doi: 10.1016/j.tig.2020.09.017

PMCID:: PMC8208824

Abstract Article PDF–864K

Select item 792005814.

Leucokinin and Associated Neuropeptides Regulate Multiple Aspects of Physiology and Behavior in Drosophila

Dick R. Nässel

Int J Mol Sci. 2021 Feb; 22(4): 1940. Published online 2021 Feb 16. doi: 10.3390/ijms22041940

PMCID:: PMC7920058

Abstract Article PDF–7.7M

Select item 764864815.

A single-cell atlas and lineage analysis of the adult Drosophila ovary

Katja Rust, Lauren E. Byrnes, Kevin Shengyang Yu, Jason S. Park, Julie B. Sneddon, Aaron D. Tward, Todd G. Nystul

Nat Commun. 2020; 11: 5628. Published online 2020 Nov 6. doi: 10.1038/s41467-020-19361-0

Correction in:: Nat Commun. 2021; 12: 5951.

PMCID:: PMC7648648

Abstract Article PDF–6.1M

Select item 733264516.

De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay

Lisenka E.L.M. Vissers, Sreehari Kalvakuri, Elke de Boer, Sinje Geuer, Machteld Oud, Inge van Outersterp, Michael Kwint, Melde Witmond, Simone Kersten, Daniel L. Polla, Dilys Weijers, Amber Begtrup, Kirsty McWalter, Anna Ruiz, Elisabeth Gabau, Jenny E.V. Morton, Christopher Griffith, Karin Weiss, Candace Gamble, James Bartley, Hilary J. Vernon, Kendra Brunet, Claudia Ruivenkamp, Sarina G. Kant, Paul Kruszka, Austin Larson, Alexandra Afenjar, Thierry Billette de Villemeur, Kimberly Nugent, the DDD Study, F. Lucy Raymond, Hanka Venselaar, Florence Demurger, Claudia Soler-Alfonso, Dong Li, Elizabeth Bhoj, Ian Hayes, Nina Powell Hamilton, Ayesha Ahmad, Rachel Fisher, Myrthe van den Born, Marjolaine Willems, Arthur Sorlin, Julian Delanne, Sebastien Moutton, Philippe Christophe, Frederic Tran Mau-Them, Antonio Vitobello, Himanshu Goel, Lauren Massingham, Chanika Phornphutkul, Jennifer Schwab, Boris Keren, Perrine Charles, Maaike Vreeburg, Lenika De Simone, George Hoganson, Maria Iascone, Donatella Milani, Lucie Evenepoel, Nicole Revencu, D. Isum Ward, Kaitlyn Burns, Ian Krantz, Sarah E. Raible, Jill R. Murrell, Kathleen Wood, Megan T. Cho, Hans van Bokhoven, Maximilian Muenke, Tjitske Kleefstra, Rolf Bodmer, Arjan P.M. de Brouwer

Am J Hum Genet. 2020 Jul 2; 107(1): 164–172. Published online 2020 Jun 17. doi: 10.1016/j.ajhg.2020.05.017