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Select item 111165281.

A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila

Alka Singh, Kandahalli Venkataranganayaka Abhilasha, Kathya R. Acharya, Haibo Liu, Niraj K. Nirala, Velayoudame Parthibane, Govind Kunduri, Thiruvaimozhi Abimannan, Jacob Tantalla, Lihua Julie Zhu, Jairaj K. Acharya, Usha R. Acharya

Nat Commun. 2024; 15: 4410. Published online 2024 May 23. doi: 10.1038/s41467-024-48851-8

PMCID:: PMC11116528

Abstract Article PDF–8.0M

Select item 111146452.

Identified peptidergic neurons in the Drosophila brain regulate insulin-producing cells, stress responses and metabolism by coexpressed short neuropeptide F and corazonin

Neval Kapan, Oleh V. Lushchak, Jiangnan Luo, Dick R. Nässel

Cell Mol Life Sci. 2012 Dec; 69(23): 4051–4066. Published online 2012 Jul 25. doi: 10.1007/s00018-012-1097-z

PMCID:: PMC11114645

Abstract Article PDF–2.3M

Select item 111133943.

Food odors trigger an endocrine response that affects food ingestion and metabolism

Oleh V. Lushchak, Mikael A. Carlsson, Dick R. Nässel

Cell Mol Life Sci. 2015 Aug; 72(16): 3143–3155. Published online 2015 Mar 18. doi: 10.1007/s00018-015-1884-4

PMCID:: PMC11113394

Abstract Article PDF–1.6M

Select item 110607184.

Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission

Renbo Mao, Jianjun Yu, Bowen Deng, Xihuimin Dai, Yuyao Du, Sujie Du, Wenxia Zhang, Yi Rao

eLife. 2024; 12: RP91927. Published online 2024 Apr 30. doi: 10.7554/eLife.91927

PMCID:: PMC11060718

Abstract Article PDF–4.3M

Select item 110242955.

The diverse roles of insulin signaling in insect behavior

Anastasia A. Weger, Clare C. Rittschof

Front Insect Sci. 2024; 4: 1360320. Published online 2024 Apr 4. doi: 10.3389/finsc.2024.1360320

PMCID:: PMC11024295

Abstract Article PDF–667K

Select item 109952906.

What can the common fruit fly teach us about stroke?: lessons learned from the hypoxic tolerant Drosophila melanogaster

Princy S. Quadros-Mennella, Kurt M. Lucin, Robin E. White

Front Cell Neurosci. 2024; 18: 1347980. Published online 2024 Mar 22. doi: 10.3389/fncel.2024.1347980

Correction in:: Front Cell Neurosci. 2024; 18: 1422866.

PMCID:: PMC10995290

Abstract Article PDF–1.2M

Select item 109904847.

Expanding the Drosophila toolkit for dual control of gene expression

Jonathan Zirin, Barbara Jusiak, Raphael Lopes, Benjamin Ewen-Campen, Justin A Bosch, Alexandria Risbeck, Corey Forman, Christians Villalta, Yanhui Hu, Norbert Perrimon

eLife. 2024; 12: RP94073. Published online 2024 Apr 3. doi: 10.7554/eLife.94073

PMCID:: PMC10990484

Abstract Article PDF–6.0M

Select item 109455088.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 108568099.

Betulinic Acid Increases the Lifespan of Drosophila melanogaster via Sir2 and FoxO Activation

Hye-Yeon Lee, Kyung-Jin Min

Nutrients. 2024 Feb; 16(3): 441. Published online 2024 Feb 1. doi: 10.3390/nu16030441

PMCID:: PMC10856809

Abstract Article PDF–2.3M

Select item 1083504710.

miR-137 regulates PTP61F, affecting insulin signaling, metabolic homeostasis, and starvation resistance in Drosophila

Hana Saedi, Girma Waro, Lea Giacchetta, Susan Tsunoda

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2319475121. Published online 2024 Jan 22. doi: 10.1073/pnas.2319475121

PMCID:: PMC10835047

Abstract Article PDF–3.0M

Select item 1079599111.

Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons

Julia Ryvkin, Liora Omesi, Yong-Kyu Kim, Mali Levi, Hadar Pozeilov, Lital Barak-Buchris, Bella Agranovich, Ifat Abramovich, Eyal Gottlieb, Avi Jacob, Dick R. Nässel, Ulrike Heberlein, Galit Shohat-Ophir

PLoS Genet. 2024 Jan; 20(1): e1011054. Published online 2024 Jan 18. doi: 10.1371/journal.pgen.1011054

PMCID:: PMC10795991

Abstract Article PDF–1.8M

Select item 1078452412.

Diabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila

Daewon Lee, Eunju Yoon, Su Jin Ham, Kunwoo Lee, Hansaem Jang, Daihn Woo, Da Hyun Lee, Sehyeon Kim, Sekyu Choi, Jongkyeong Chung

Nat Commun. 2024; 15: 468. Published online 2024 Jan 11. doi: 10.1038/s41467-024-44747-9

PMCID:: PMC10784524

Abstract Article PDF–4.8M

Select item 1069517413.

Mitochondrial metabolism in Drosophila macrophage-like cells regulates body growth via modulation of cytokine and insulin signaling

Shrivani Sriskanthadevan-Pirahas, Abdul Qadeer Tinwala, Michael J. Turingan, Shahoon Khan, Savraj S. Grewal

Biol Open. 2023 Nov 15; 12(11): bio059968. Published online 2023 Nov 29. doi: 10.1242/bio.059968

PMCID:: PMC10695174

Abstract Article PDF–2.4M

Select item 1067176714.

Yeast Hydrolysate Inhibits Lipid Accumulation via Regulation of Lipid Accumulation-Related Genes in a Drosophila Model of High-Sugar Diet-Induced Obesity

Nari Kim, Yejin Ahn, Kayoung Ko, Boyun Kim, Kisoo Han, Hyung Joo Suh, Jewon Jung, Ki-Bae Hong

Int J Mol Sci. 2023 Nov; 24(22): 16302. Published online 2023 Nov 14. doi: 10.3390/ijms242216302

PMCID:: PMC10671767

Abstract Article PDF–2.7M

Select item 1067006415.

Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

Sentiljana Gumeni, Maria Lamprou, Zoi Evangelakou, Maria S. Manola, Ioannis P. Trougakos

Cells. 2023 Nov; 12(22): 2650. Published online 2023 Nov 18. doi: 10.3390/cells12222650

PMCID:: PMC10670064

Abstract Article PDF–2.1M

Select item 1066833616.

Early-life hypoxia alters adult physiology and reduces stress resistance and lifespan in Drosophila

Danielle M. Polan, Mohammed Alansari, Byoungchun Lee, Savraj S. Grewal

J Exp Biol. 2020 Nov 15; 223(22): jeb226027. Published online 2020 Nov 23. doi: 10.1242/jeb.226027

PMCID:: PMC10668336

Abstract Article

Select item 1065646117.

A low-sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

Jason W. Millington, Puja Biswas, Charlotte Chao, Yi Han Xia, Lianna W. Wat, George P. Brownrigg, Ziwei Sun, Paige J. Basner-Collins, Ramon I. Klein Geltink, Elizabeth J. Rideout

Development. 2022 Mar 15; 149(6): dev200491. Published online 2022 Mar 28. doi: 10.1242/dev.200491

PMCID:: PMC10656461

Abstract Article

Select item 1065109218.

A Drosophila model targets Eiger/TNFα to alleviate obesity-related insulin resistance and macrophage infiltration

Zhasmine Mirzoyan, Alice Valenza, Sheri Zola, Carola Bonfanti, Lorenzo Arnaboldi, Nicholas Ferrari, John Pollard, Valeria Lupi, Matteo Cassinelli, Matteo Frattaroli, Mehtap Sahin, Maria Enrica Pasini, Paola Bellosta

Dis Model Mech. 2023 Nov 1; 16(11): dmm050388. Published online 2023 Nov 6. doi: 10.1242/dmm.050388