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Items: 1 to 20 of 80

1.
E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis
Yasuko Kajimura, Akihiko Taguchi, Yuko Nagao, Kaoru Yamamoto, Konosuke Masuda, Kensuke Shibata, Yoichi Asaoka, Makoto Furutani-Seiki, Yukio Tanizawa, Yasuharu Ohta
Commun Biol. 2024; 7: 527. Published online 2024 May 7. doi: 10.1038/s42003-024-06099-4
PMCID:
PMC11076557
AbstractArticlePDF–2.5M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Ablation of cDC2 development by triple mutations within the Zeb2 enhancer
Tian-Tian Liu, Sunkyung Kim, Pritesh Desai, Do-Hyun Kim, Xiao Huang, Stephen T. Ferris, Renee Wu, Feiya Ou, Takeshi Egawa, Steven J. Van Dyken, Michael S. Diamond, Peter F. Johnson, Masato Kubo, Theresa L. Murphy, Kenneth M. Murphy
Nature. Author manuscript; available in PMC 2023 Jul 20.
Published in final edited form as: Nature. 2022 Jul; 607(7917): 142–148. Published online 2022 Jun 22. doi: 10.1038/s41586-022-04866-z
PMCID:
PMC10358283
AbstractArticlePDF–3.8M
4.
The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene
Nisha Misra, Manohar Damara, Tao Ye, Pierre Chambon
Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2214062120. Published online 2023 Feb 15. doi: 10.1073/pnas.2214062120
PMCID:
PMC9974474
AbstractArticlePDF–1.1M
5.
High-Fat Diet–Induced DeSUMOylation of E4BP4 Promotes Lipid Droplet Biogenesis and Liver Steatosis in Mice
Sujuan Wang, Meichan Yang, Pei Li, Julian Sit, Audrey Wong, Kyle Rodrigues, Daniel Lank, Deqiang Zhang, Kezhong Zhang, Lei Yin, Xin Tong
Diabetes. 2023 Mar; 72(3): 348–361. Published online 2022 Dec 12. doi: 10.2337/db22-0332
PMCID:
PMC9935497
AbstractArticlePDF–19M
6.
NFIL3 deficiency alleviates EAE through regulating different immune cell subsets
Zhigang Chen, Rong Fan, Jie Liang, Zexiu Xiao, Junlong Dang, Jun Zhao, Ruihui Weng, Cansheng Zhu, Song Guo Zheng, Ying Jiang
J Adv Res. 2022 Jul; 39: 225–235. Published online 2021 Nov 14. doi: 10.1016/j.jare.2021.10.011
PMCID:
PMC9263648
AbstractArticlePDF–3.5M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis
Laura Ducimetière, Giulia Lucchiari, Gioana Litscher, Marc Nater, Laura Heeb, Nicolás Gonzalo Nuñez, Laura Wyss, Dominik Burri, Marijne Vermeer, Julia Gschwend, Andreas E. Moor, Burkhard Becher, Maries van den Broek, Sonia Tugues
Proc Natl Acad Sci U S A. 2021 Jul 6; 118(27): e2026271118. Published online 2021 Jun 28. doi: 10.1073/pnas.2026271118
PMCID:
PMC8271692
AbstractArticlePDF–4.2M
9.
Hepatic E4BP4 induction promotes lipid accumulation by suppressing AMPK signaling in response to chemical or diet-induced ER stress
Meichan Yang, Deqiang Zhang, Zifeng Zhao, Julian Sit, Mischael Saint-Sume, Omar Shabandri, Kezhong Zhang, Lei Yin, Xin Tong
FASEB J. Author manuscript; available in PMC 2021 Mar 31.
Published in final edited form as: FASEB J. 2020 Oct; 34(10): 13533–13547. Published online 2020 Aug 11. doi: 10.1096/fj.201903292RR
PMCID:
PMC8011030
AbstractArticlePDF–1.2M
10.
An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets
Huiyuan Zhang, Asaf Madi, Nir Yosef, Norio Chihara, Amit Awasthi, Caroline Pot, Conner Lambden, Amitabh Srivastava, Patrick R. Burkett, Jackson Nyman, Elena Christian, Yasaman Etminan, Annika Lee, Helene Stroh, Junrong Xia, Katarzyna Karwacz, Pratiksha I. Thakore, Nandini Acharya, Alexandra Schnell, Chao Wang, Lionel Apetoh, Orit Rozenblatt-Rosen, Ana C. Anderson, Aviv Regev, Vijay K. Kuchroo
Cell Rep. Author manuscript; available in PMC 2020 Dec 29.
Published in final edited form as: Cell Rep. 2020 Nov 24; 33(8): 108433. doi: 10.1016/j.celrep.2020.108433
PMCID:
PMC7771052
AbstractArticlePDF–2.9M
11.
Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice
Yanke Lin, Shuai Wang, Lu Gao, Ziyue Zhou, Zemin Yang, Jingpan Lin, Shujing Ren, Huijie Xing, Baojian Wu
Theranostics. 2021; 11(1): 426–444. Published online 2021 Jan 1. doi: 10.7150/thno.50281
PMCID:
PMC7681083
AbstractArticlePDF–3.6M
12.
An NF-κB–driven lncRNA orchestrates colitis and circadian clock
Shuai Wang, Yanke Lin, Feng Li, Zifei Qin, Ziyue Zhou, Lu Gao, Zemin Yang, Zhigang Wang, Baojian Wu
Sci Adv. 2020 Oct; 6(42): eabb5202. Published online 2020 Oct 14. doi: 10.1126/sciadv.abb5202
PMCID:
PMC7556837
AbstractArticlePDF–7.5M
13.
E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases
Zijun Wang, Ming Zhao, Jinghua Yin, Limin Liu, Longyuan Hu, Yi Huang, Aiyun Liu, Jiajun Ouyang, Xiaoli Min, Shijia Rao, Wenhui Zhou, Haijing Wu, Akihiko Yoshimura, Qianjin Lu
J Clin Invest. 2020 Jul 1; 130(7): 3717–3733. Published online 2020 Jun 2. doi: 10.1172/JCI129018
PMCID:
PMC7324209
AbstractArticlePDF–12M
14.
Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells
Qianli Wang, Michelle L. Robinette, Cyrielle Billon, Patrick L. Collins, Jennifer K. Bando, José Luís Fachi, Cristiane Sécca, Sofia I. Porter, Ankita Saini, Susan Gilfillan, Laura A. Solt, Erik S. Musiek, Eugene M. Oltz, Thomas P. Burris, Marco Colonna
Sci Immunol. Author manuscript; available in PMC 2020 Apr 4.
Published in final edited form as: Sci Immunol. 2019 Oct 4; 4(40): eaay7501. doi: 10.1126/sciimmunol.aay7501
PMCID:
PMC6911370
AbstractArticlePDF–1.1M
15.
The transcription factor NFIL3 controls regulatory T-cell function and stability
Hyeong Su Kim, Hyogon Sohn, Sung Woong Jang, Gap Ryol Lee
Exp Mol Med. 2019 Jul; 51(7): 80. Published online 2019 Jul 16. doi: 10.1038/s12276-019-0280-9
PMCID:
PMC6802641
AbstractArticlePDF–2.3M
16.
An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Prachi Bagadia, Xiao Huang, Tiantian Liu, Vivek Durai, Gary E. Grajales-Reyes, Maximilian Nitschke, Zora Modrusan, Jeffrey M. Granja, Ansuman T. Satpathy, Carlos G. Briseño, Marco Gargaro, Arifumi Iwata, Sunkyung Kim, Howard Y. Chang, Andrey S. Shaw, Theresa L. Murphy, Kenneth M. Murphy
Nat Immunol. Author manuscript; available in PMC 2020 Feb 12.
Published in final edited form as: Nat Immunol. 2019 Sep; 20(9): 1174–1185. Published online 2019 Aug 12. doi: 10.1038/s41590-019-0449-3
PMCID:
PMC6707889
AbstractArticlePDF–1.2M
17.
Functional D-box sequences reset the circadian clock and drive mRNA rhythms
Hikari Yoshitane, Yoshimasa Asano, Aya Sagami, Seinosuke Sakai, Yutaka Suzuki, Hitoshi Okamura, Wataru Iwasaki, Haruka Ozaki, Yoshitaka Fukada
Commun Biol. 2019; 2: 300. Published online 2019 Aug 8. doi: 10.1038/s42003-019-0522-3
PMCID:
PMC6687812
AbstractArticlePDF–1.2M
18.
The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition
Fangjun Yu, Tianpeng Zhang, Cui Zhou, Haiman Xu, Lianxia Guo, Min Chen, Baojian Wu
Theranostics. 2019; 9(10): 2754–2767. Published online 2019 Apr 13. doi: 10.7150/thno.33395
PMCID:
PMC6568180
AbstractArticlePDF–1.9M
19.
NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology
Susan Schlenner, Emanuela Pasciuto, Vasiliki Lagou, Oliver Burton, Teresa Prezzemolo, Steffie Junius, Carlos P Roca, Cyril Seillet, Cynthia Louis, James Dooley, Kylie Luong, Erika Van Nieuwenhove, Ian P Wicks, Gabrielle Belz, Stéphanie Humblet-Baron, Carine Wouters, Adrian Liston
Ann Rheum Dis. 2019 Mar; 78(3): 342–349. Published online 2018 Dec 14. doi: 10.1136/annrheumdis-2018-213764
PMCID:
PMC6390028
AbstractArticlePDF–7.4M
20.
Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency
Matthew T. Rätsep, Stephen D. Moore, Salema Jafri, Melissa Mitchell, Hugh J. M. Brady, Ofer Mandelboim, Mark Southwood, Nicholas W. Morrell, Francesco Colucci, Mark L. Ormiston
Am J Physiol Lung Cell Mol Physiol. 2018 Dec 1; 315(6): L977–L990. Published online 2018 Sep 20. doi: 10.1152/ajplung.00477.2017
PMCID:
PMC6337009
AbstractArticle

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