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Select item 115361191.

eIF4F controls ERK MAPK signaling in melanomas with BRAF and NRAS mutations

Barbora Valcikova, Natalia Vadovicova, Karolina Smolkova, Magdalena Zacpalova, Pavel Krejci, Shannon Lee, Jens Rauch, Walter Kolch, Alexander von Kriegsheim, Anna Dorotikova, Zdenek Andrysik, Rachel Vichova, Ondrej Vacek, Karel Soucek, Stjepan Uldrijan

Proc Natl Acad Sci U S A. 2024 Oct 29; 121(44): e2321305121. Published online 2024 Oct 22. doi: 10.1073/pnas.2321305121

PMCID:: PMC11536119

Abstract Article PDF–5.7M

Select item 112969142.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 110639023.

Human eukaryotic initiation factor 4G directly binds the 40S ribosomal subunit to promote efficient translation

Nancy Villa, Christopher S. Fraser

J Biol Chem. 2024 May; 300(5): 107242. Published online 2024 Apr 1. doi: 10.1016/j.jbc.2024.107242

PMCID:: PMC11063902

Abstract Article PDF–2.1M

Select item 110211804.

The eukaryotic translation initiation factor eIF4E unexpectedly acts in splicing thereby coupling mRNA processing with translation: eIF4E induces widescale splicing reprogramming providing system‐wide connectivity between splicing, nuclear mRNA export and translation

Katherine L. B. Borden

Bioessays. 2024 Jan; 46(1): 2300145. Published online 2023 Nov 5. doi: 10.1002/bies.202300145

PMCID:: PMC11021180

Abstract Article PDF–1.1M

Select item 109902775.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 108791986.

miR-483-5p orchestrates the initiation of protein synthesis by facilitating the decrease in phosphorylated Ser209eIF4E and 4E-BP1 levels

Siranjeevi Nagaraj, Anna Stankiewicz-Drogon, Edward Darzynkiewicz, Urszula Wojda, Renata Grzela

Sci Rep. 2024; 14: 4237. Published online 2024 Feb 20. doi: 10.1038/s41598-024-54154-1

PMCID:: PMC10879198

Abstract Article PDF–1.8M

Select item 106951837.

mTOR pathway candidate genes and physical activity interaction on breast cancer risk in Black women from the Women’s Circle of Health Study

Mmadili N. Ilozumba, Lusine Yaghjyan, Susmita Datta, Jinying Zhao, Zhihong Gong, Chi-Chen Hong, Kathryn L. Lunetta, Gary Zirpoli, Elisa V. Bandera, Julie R. Palmer, Song Yao, Christine B. Ambrosone, Ting-Yuan David Cheng

Breast Cancer Res Treat. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Breast Cancer Res Treat. 2023 May; 199(1): 137–146. Published online 2023 Mar 8. doi: 10.1007/s10549-023-06902-6

PMCID:: PMC10695183

Abstract Article PDF–128K

Select item 106179818.

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

Nora Schmidt, Sabina Ganskih, Yuanjie Wei, Alexander Gabel, Sebastian Zielinski, Hasmik Keshishian, Caleb A. Lareau, Liv Zimmermann, Jana Makroczyova, Cadence Pearce, Karsten Krey, Thomas Hennig, Sebastian Stegmaier, Lambert Moyon, Marc Horlacher, Simone Werner, Jens Aydin, Marco Olguin-Nava, Ramya Potabattula, Anuja Kibe, Lars Dölken, Redmond P. Smyth, Neva Caliskan, Annalisa Marsico, Christine Krempl, Jochen Bodem, Andreas Pichlmair, Steven A. Carr, Petr Chlanda, Florian Erhard, Mathias Munschauer

Cell. 2023 Oct 26; 186(22): 4834–4850.e23. doi: 10.1016/j.cell.2023.09.002

PMCID:: PMC10617981

Abstract Article

Select item 104846829.

Paralogous translation factors target distinct mRNAs to differentially regulate tolerance to oxidative stress in yeast

Joanne Cunningham, Aristeidis P Sfakianos, Paraskevi Kritsiligkou, Christopher J Kershaw, Alan J Whitmarsh, Simon J Hubbard, Mark P Ashe, Chris M Grant

Nucleic Acids Res. 2023 Sep 8; 51(16): 8820–8835. Published online 2023 Jul 14. doi: 10.1093/nar/gkad568

PMCID:: PMC10484682

Abstract Article PDF–1.8M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 976969811.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 956995512.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 955043613.

Expression of eIF4E Gene in Glioma and Its Sensitivity to Oxidative Stress

Jian Liang, Yaoqiang Yang, Xing Li, Guangmou Cai, Jianxuan Cao, Bo Zhang

Oxid Med Cell Longev. 2022; 2022: 5413035. Published online 2022 Oct 3. doi: 10.1155/2022/5413035

PMCID:: PMC9550436

Abstract Article PDF–2.1M

Select item 952399714.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 943756315.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 934561416.

Down-regulated Circ_0000190 promotes cervical cancer by facilitating the activity of proto-oncogene protein EIF4E

Chengcheng Yang, Jia Xie, Qian Chen, Yisi Yang

Cell Cycle. 2022; 21(13): 1349–1359. Published online 2022 Apr 13. doi: 10.1080/15384101.2021.2018212

PMCID:: PMC9345614

Abstract Article PDF–3.5M

Select item 927928517.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973618.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 907732319.

RNA m⁶A methylation regulates dissemination of cancer cells by modulating expression and membrane localization of β-catenin

Jiexin Li, Guoyou Xie, Yifan Tian, Wanglin Li, Yingmin Wu, Feng Chen, Yu Lin, Xinyao Lin, Shannon Wing-Ngor Au, Jie Cao, Weiling He, Hongsheng Wang

Mol Ther. 2022 Apr 6; 30(4): 1578–1596. Published online 2022 Jan 14. doi: 10.1016/j.ymthe.2022.01.019

PMCID:: PMC9077323

Abstract Article PDF–5.6M

Select item 903609220.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

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