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Select item 102333681.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92098112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 84212043.

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu

Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680

PMCID:: PMC8421204

Abstract Article PDF–2.9M

Select item 62157134.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 56618855.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 56002546.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 55958087.

Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment

Kristian Shulist, Eric Yen, Susanne Kaitna, Allen Leary, Alexandra Decterov, Debarun Gupta, Jackie Vogel

Sci Rep. 2017; 7: 11398. Published online 2017 Sep 12. doi: 10.1038/s41598-017-11789-7

Correction in:: Sci Rep. 2018; 8: 2513.

PMCID:: PMC5595808

Abstract Article PDF–5.9M

Select item 55929458.

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

Vasso Makrantoni, Adam Ciesiolka, Conor Lawless, Josefin Fernius, Adele Marston, David Lydall, Michael J. R. Stark

G3 (Bethesda) 2017 Sep; 7(9): 3203–3215. Published online 2017 Jul 28. doi: 10.1534/g3.117.300089

PMCID:: PMC5592945

Abstract Article PDF–1.7M

Select item 50865209.

Ribosome-Associated Mba1 Escorts Cox2 from Insertion Machinery to Maturing Assembly Intermediates

Isotta Lorenzi, Silke Oeljeklaus, Christin Ronsör, Bettina Bareth, Bettina Warscheid, Peter Rehling, Sven Dennerlein

Mol Cell Biol. 2016 Nov 15; 36(22): 2782–2793. Prepublished online 2016 Aug 22. Published online 2016 Oct 28. doi: 10.1128/MCB.00361-16

PMCID:: PMC5086520

Abstract Article PDF–2.4M

Select item 505508310.

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, Richard Kangda Wang, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser

Cell. 2016 Oct 6; 167(2): 553–565.e12. doi: 10.1016/j.cell.2016.09.007

PMCID:: PMC5055083

Abstract Article PDF–3.9M

Select item 417536511.

The Mitochondrial ADP/ATP Carrier Associates with the Inner Membrane Presequence Translocase in a Stoichiometric Manner

Carola S. Mehnert, Heike Rampelt, Michael Gebert, Silke Oeljeklaus, Sandra G. Schrempp, Lioba Kochbeck, Bernard Guiard, Bettina Warscheid, Martin van der Laan

J Biol Chem. 2014 Sep 26; 289(39): 27352–27362. Published online 2014 Aug 14. doi: 10.1074/jbc.M114.556498

PMCID:: PMC4175365

Abstract Article PDF–1.5M

Select item 375707512.

High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8

Maria J. Aristizabal, Gian Luca Negri, Joris J. Benschop, Frank C. P. Holstege, Nevan J. Krogan, Michael S. Kobor

PLoS Genet. 2013 Aug; 9(8): e1003758. Published online 2013 Aug 29. doi: 10.1371/journal.pgen.1003758

PMCID:: PMC3757075

Abstract Article PDF–4.4M

Select item 351004413.

The Yeast SR-Like Protein Npl3 Links Chromatin Modification to mRNA Processing

Erica A. Moehle, Colm J. Ryan, Nevan J. Krogan, Tracy L. Kress, Christine Guthrie

PLoS Genet. 2012 Nov; 8(11): e1003101. Published online 2012 Nov 29. doi: 10.1371/journal.pgen.1003101

PMCID:: PMC3510044

Abstract Article PDF–3.4M

Select item 331716014.

Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs

Sara Sharifpoor, Dewald van Dyk, Michael Costanzo, Anastasia Baryshnikova, Helena Friesen, Alison C. Douglas, Ji-Young Youn, Benjamin VanderSluis, Chad L. Myers, Balázs Papp, Charles Boone, Brenda J. Andrews

Genome Res. 2012 Apr; 22(4): 791–801. doi: 10.1101/gr.129213.111

PMCID:: PMC3317160

Abstract Article PDF–998K

Select item 319815615.

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

Suzanne Hoppins, Sean R. Collins, Ann Cassidy-Stone, Eric Hummel, Rachel M. DeVay, Laura L. Lackner, Benedikt Westermann, Maya Schuldiner, Jonathan S. Weissman, Jodi Nunnari

J Cell Biol. 2011 Oct 17; 195(2): 323–340. doi: 10.1083/jcb.201107053

PMCID:: PMC3198156

Abstract Article PDF–4.1M

Select item 308421316.

The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components

Peter C. Stirling, Michelle S. Bloom, Tejomayee Solanki-Patil, Stephanie Smith, Payal Sipahimalani, Zhijian Li, Megan Kofoed, Shay Ben-Aroya, Kyungjae Myung, Philip Hieter

PLoS Genet. 2011 Apr; 7(4): e1002057. Published online 2011 Apr 28. doi: 10.1371/journal.pgen.1002057