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Items: 1 to 20 of 40

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis
Biqing Wang, Xuening Tang, Liu Yao, Yuxin Wang, Zhipeng Chen, Mengqi Li, Naishi Wu, Dawei Wu, Xiangchen Dai, Hongfeng Jiang, Ding Ai
J Clin Invest. 2022 May 16; 132(10): e154217. Published online 2022 May 16. doi: 10.1172/JCI154217
PMCID:
PMC9106359
AbstractArticlePDF–16M
3.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
Liquid-like protein interactions catalyze assembly of endocytic vesicles
Kasey J. Day, Grace Kago, Liping Wang, J Blair Richter, Carl C. Hayden, Eileen M. Lafer, Jeanne C. Stachowiak
Nat Cell Biol. Author manuscript; available in PMC 2021 Oct 5.
Published in final edited form as: Nat Cell Biol. 2021 Apr; 23(4): 366–376. Published online 2021 Apr 5. doi: 10.1038/s41556-021-00646-5
PMCID:
PMC8035231
AbstractArticlePDF–2.2M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
A trans-eQTL network regulates osteoclast multinucleation and bone mass
Marie Pereira, Jeong-Hun Ko, John Logan, Hayley Protheroe, Kee-Beom Kim, Amelia Li Min Tan, Peter I Croucher, Kwon-Sik Park, Maxime Rotival, Enrico Petretto, JH Duncan Bassett, Graham R Williams, Jacques Behmoaras
eLife. 2020; 9: e55549. Published online 2020 Jun 19. doi: 10.7554/eLife.55549
PMCID:
PMC7351491
AbstractArticlePDF–5.1M
8.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
9.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
10.
Redundant and nonredundant organismal functions of EPS15 and EPS15L1
Cinzia Milesi, Paola Alberici, Benedetta Pozzi, Amanda Oldani, Galina V Beznoussenko, Andrea Raimondi, Blanche Ekalle Soppo, Stefania Amodio, Giusi Caldieri, Maria Grazia Malabarba, Giovanni Bertalot, Stefano Confalonieri, Dario Parazzoli, Alexander A Mironov, Carlo Tacchetti, Pier Paolo Di Fiore, Sara Sigismund, Nina Offenhäuser
Life Sci Alliance. 2019 Feb; 2(1): e201800273. Published online 2019 Jan 28. doi: 10.26508/lsa.201800273
PMCID:
PMC6350104
AbstractArticlePDF–1.7M
11.
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon
eLife. 2018; 7: e32866. Published online 2018 Apr 20. doi: 10.7554/eLife.32866
PMCID:
PMC5927771
AbstractArticlePDF–9.1M
12.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
13.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
14.
Hierarchical CRMP2 posttranslational modifications control NaV1.7 function
Erik T. Dustrude, Aubin Moutal, Xiaofang Yang, Yuying Wang, May Khanna, Rajesh Khanna
Proc Natl Acad Sci U S A. 2016 Dec 27; 113(52): E8443–E8452. Published online 2016 Dec 8. doi: 10.1073/pnas.1610531113
PMCID:
PMC5206544
AbstractArticlePDF–6.2M
15.
Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS
Jennifer A. Watson, Bula J. Bhattacharyya, Jada H. Vaden, Julie A. Wilson, Mert Icyuz, Alan D. Howard, Edward Phillips, Tara M. DeSilva, Gene P. Siegal, Andrew J. Bean, Gwendalyn D. King, Scott E. Phillips, Richard J. Miller, Scott M. Wilson
PLoS Genet. 2015 Jun; 11(6): e1005290. Published online 2015 Jun 26. doi: 10.1371/journal.pgen.1005290
PMCID:
PMC4482608
AbstractArticlePDF–5.7M
16.
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen
Hibret A. Adissu, Jeanne Estabel, David Sunter, Elizabeth Tuck, Yvette Hooks, Damian M. Carragher, Kay Clarke, Natasha A. Karp, Sanger Mouse Genetics Project, Susan Newbigging, Nora Jones, Lily Morikawa, Jacqueline K. White, Colin McKerlie
Dis Model Mech. 2014 May; 7(5): 515–524. Published online 2014 Mar 20. doi: 10.1242/dmm.015263
PMCID:
PMC4007403
AbstractArticle
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers
Benedetta Pozzi, Stefania Amodio, Caterina Lucano, Anna Sciullo, Simona Ronzoni, Daniela Castelletti, Thure Adler, Irina Treise, Ingrid Holmberg Betsholtz, Birgit Rathkolb, Dirk H. Busch, Eckhard Wolf, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Christer Betsholtz, Stefano Casola, Pier Paolo Di Fiore, Nina Offenhäuser
PLoS One. 2012; 7(11): e50818. Published online 2012 Nov 30. doi: 10.1371/journal.pone.0050818
Correction in:
PLoS One. 2013; 8(5): 10.1371/annotation/9c1c760a-8477-499d-a194-5ed87ffa6c6a.
PMCID:
PMC3511280
AbstractArticlePDF–2.7M
19.
Sequence based characterization of structural variation in the mouse genome
Binnaz Yalcin, Kim Wong, Avigail Agam, Martin Goodson, Thomas M. Keane, Xiangchao Gan, Christoffer Nellåker, Leo Goodstadt, Jérôme Nicod, Amarjit Bhomra, Polinka Hernandez-Pliego, Helen Whitley, James Cleak, Rebekah Dutton, Deborah Janowitz, Richard Mott, David J. Adams, Jonathan Flint
Nature. Author manuscript; available in PMC 2012 Aug 28.
Published in final edited form as: Nature. 2011 Sep 14; 477(7364): 326–329. Published online 2011 Sep 14. doi: 10.1038/nature10432
PMCID:
PMC3428933
AbstractArticlePDF–396K
20.
The clathrin adaptor Dab2 recruits EH domain scaffold proteins to regulate integrin β1 endocytosis
Anjali Teckchandani, Erin E. Mulkearns, Timothy W. Randolph, Natalie Toida, Jonathan A. Cooper
Mol Biol Cell. 2012 Aug 1; 23(15): 2905–2916. doi: 10.1091/mbc.E11-12-1007
PMCID:
PMC3408417
AbstractArticlePDF–3.8M

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