PMC Links for GEO Profiles (Select 35517746) - PMC

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Items: 11

Select item 26697321.

A Structure-Based Approach to Ligand Discovery for 2C-Methyl-d-erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy

Nicola L. Ramsden, Lori Buetow, Alice Dawson, Lauris A. Kemp, Venkatsubramanian Ulaganathan, Ruth Brenk, Gerhard Klebe, William N. Hunter

J Med Chem. 2009 Apr 23; 52(8): 2531–2542. Published online 2009 Mar 25. doi: 10.1021/jm801475n

PMCID:: PMC2669732

Abstract Article PDF–1.7M

Select item 19524482.

A double mutation of Escherichia coli 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate

Tanja Sgraja, Lauris E. Kemp, Nicola Ramsden, William N. Hunter

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1; 61(Pt 7): 625–629. Published online 2005 Jun 30. doi: 10.1107/S1744309105018762

PMCID:: PMC1952448

Abstract Article PDF–822K

Select item 16814823.

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

Tomoya Baba, Takeshi Ara, Miki Hasegawa, Yuki Takai, Yoshiko Okumura, Miki Baba, Kirill A Datsenko, Masaru Tomita, Barry L Wanner, Hirotada Mori

Mol Syst Biol. 2006; 2: 2006.0008. Published online 2006 Feb 21. doi: 10.1038/msb4100050

PMCID:: PMC1681482

Abstract Article PDF–400K

Select item 16814814.

Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110

Koji Hayashi, Naoki Morooka, Yoshihiro Yamamoto, Katsutoshi Fujita, Katsumi Isono, Sunju Choi, Eiichi Ohtsubo, Tomoya Baba, Barry L Wanner, Hirotada Mori, Takashi Horiuchi

Mol Syst Biol. 2006; 2: 2006.0007. Published online 2006 Feb 21. doi: 10.1038/msb4100049

PMCID:: PMC1681481

Abstract Article PDF–141K

Select item 13252005.

Escherichia coli K-12: a cooperatively developed annotation snapshot—2005

Monica Riley, Takashi Abe, Martha B. Arnaud, Mary K.B. Berlyn, Frederick R. Blattner, Roy R. Chaudhuri, Jeremy D. Glasner, Takashi Horiuchi, Ingrid M. Keseler, Takehide Kosuge, Hirotada Mori, Nicole T. Perna, Guy Plunkett, III, Kenneth E. Rudd, Margrethe H. Serres, Gavin H. Thomas, Nicholas R. Thomson, David Wishart, Barry L. Wanner

Nucleic Acids Res. 2006; 34(1): 1–9. Published online 2006 Jan 5. doi: 10.1093/nar/gkj405

PMCID:: PMC1325200

Abstract Article PDF–204K

Select item 12215436.

Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis.

N Campos, M Rodríguez-Concepción, S Sauret-Güeto, F Gallego, L M Lois, A Boronat

Biochem J. 2001 Jan 1; 353(Pt 1): 59–67.

PMCID:: PMC1221543

Summary PDF–241K

Select item 1968197.

A new gene involved in stationary-phase survival located at 59 minutes on the Escherichia coli chromosome.

C Li, J K Ichikawa, J J Ravetto, H C Kuo, J C Fu, S Clarke

J Bacteriol. 1994 Oct; 176(19): 6015–6022. doi: 10.1128/jb.176.19.6015-6022.1994

Correction in:: J Bacteriol. 1996 Apr; 178(7): 2159.

PMCID:: PMC196819

Summary Page Browse PDF–1.6M

Select item 1396178.

Characterization of the Depletion of 2-C-Methyl-d-Erythritol-2,4-Cyclodiphosphate Synthase in Escherichia coli and Bacillus subtilis

Tracey L. Campbell, Eric D. Brown

J Bacteriol. 2002 Oct; 184(20): 5609–5618. doi: 10.1128/JB.184.20.5609-5618.2002

PMCID:: PMC139617

Abstract Article PDF–1.0M

Select item 1244479.

Structure of 2C-methyl-d-erythritol 2,4- cyclodiphosphate synthase: An essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development

Lauris E. Kemp, Charles S. Bond, William N. Hunter

Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 6591–6596. Published online 2002 May 7. doi: 10.1073/pnas.102679799

PMCID:: PMC124447

Abstract Article PDF–653K

Select item 1835910.

Cytidine 5′-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol

Felix Rohdich, Juraithip Wungsintaweekul, Monika Fellermeier, Silvia Sagner, Stefan Herz, Klaus Kis, Wolfgang Eisenreich, Adelbert Bacher, Meinhart H. Zenk

Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21): 11758–11763. doi: 10.1073/pnas.96.21.11758

PMCID:: PMC18359

Abstract Article PDF–202K

Select item 1595511.

Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-d-erythritol 2-phosphate to 2C-methyl-d-erythritol 2,4-cyclodiphosphate

Stefan Herz, Juraithip Wungsintaweekul, Christoph A. Schuhr, Stefan Hecht, Holger Lüttgen, Sylvia Sagner, Monika Fellermeier, Wolfgang Eisenreich, Meinhart H. Zenk, Adelbert Bacher, Felix Rohdich

Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6): 2486–2490. Published online 2000 Feb 29. doi: 10.1073/pnas.040554697