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Select item 85702741.

The Mutant β^E202K Sliding Clamp Protein Impairs DNA Polymerase III Replication Activity

Caleb Homiski, Michelle K. Scotland, Vignesh M. P. Babu, Sundari Chodavarapu, Robert W. Maul, Jon M. Kaguni, Mark D. Sutton

J Bacteriol. 2021 Dec; 203(23): e00303-21. Prepublished online 2021 Sep 20. Published online 2021 Nov 5. doi: 10.1128/JB.00303-21

PMCID:: PMC8570274

Abstract Article PDF–3.1M

Select item 85702712.

Elevated Levels of the Escherichia colinrdAB-Encoded Ribonucleotide Reductase Counteract the Toxicity Caused by an Increased Abundance of the β Clamp

Vignesh M. P. Babu, Caleb Homiski, Michelle K. Scotland, Sundari Chodavarapu, Jon M. Kaguni, Mark D. Sutton

J Bacteriol. 2021 Dec; 203(23): e00304-21. Prepublished online 2021 Sep 20. Published online 2021 Nov 5. doi: 10.1128/JB.00304-21

PMCID:: PMC8570271

Abstract Article PDF–2.3M

Select item 65118373.

Binding of the regulatory domain of MutL to the sliding β-clamp is species specific

Ahmad W Almawi, Michelle K Scotland, Justin R Randall, Linda Liu, Heather K Martin, Lauralicia Sacre, Yao Shen, Monica C Pillon, Lyle A Simmons, Mark D Sutton, Alba Guarné

Nucleic Acids Res. 2019 May 21; 47(9): 4831–4842. Published online 2019 Mar 27. doi: 10.1093/nar/gkz115

PMCID:: PMC6511837

Abstract Article PDF–3.4M

Select item 60102754.

Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation

Amit Bhardwaj, Debarghya Ghose, Krishan Gopal Thakur, Dipak Dutta

PLoS One. 2018; 13(6): e0199559. Published online 2018 Jun 20. doi: 10.1371/journal.pone.0199559

PMCID:: PMC6010275

Abstract Article PDF–6.0M

Select item 53971845.

Dynamic assembly of Hda and the sliding clamp in the regulation of replication licensing

Jin S. Kim, Michael T. Nanfara, Sundari Chodavarapu, Kyeong S. Jin, Vignesh M. P. Babu, Mohamed A. Ghazy, Scisung Chung, Jon M. Kaguni, Mark D. Sutton, Yunje Cho

Nucleic Acids Res. 2017 Apr 20; 45(7): 3888–3905. Published online 2017 Feb 7. doi: 10.1093/nar/gkx081

PMCID:: PMC5397184

Abstract Article PDF–11M

Select item 47030706.

cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ

Rafael Fernandez-Leiro, Julian Conrad, Sjors HW Scheres, Meindert H Lamers

eLife. 2015; 4: e11134. Published online 2015 Oct 24. doi: 10.7554/eLife.11134

PMCID:: PMC4703070

Abstract Article PDF–5.1M

Select item 42627487.

Kinetic analysis of PCNA clamp binding and release in the clamp loading reaction catalyzed by Saccharomyces cerevisiae replication factor C

Melissa R. Marzahn, Jaclyn N. Hayner, Jennifer A. Meyer, Linda B. Bloom

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Jan; 1854(1): 31–38. Published online 2014 Oct 23. doi: 10.1016/j.bbapap.2014.09.019

PMCID:: PMC4262748

Abstract Article PDF–988K

Select item 41238558.

The binary protein-protein interaction landscape of Escherichia coli

Seesandra V. Rajagopala, Patricia Sikorski, Ashwani Kumar, Roberto Mosca, James Vlasblom, Roland Arnold, Jonathan Franca-Koh, Suman B. Pakala, Sadhna Phanse, Arnaud Ceol, Roman Häuser, Gabriella Siszler, Stefan Wuchty, Andrew Emili, Mohan Babu, Patrick Aloy, Rembert Pieper, Peter Uetz

Nat Biotechnol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Nat Biotechnol. 2014 Mar; 32(3): 285–290. Published online 2014 Feb 23. doi: 10.1038/nbt.2831

PMCID:: PMC4123855

Abstract Article PDF–1.1M

Select item 40405709.

Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis

James E. Kath, Slobodan Jergic, Justin M. H. Heltzel, Deena T. Jacob, Nicholas E. Dixon, Mark D. Sutton, Graham C. Walker, Joseph J. Loparo

Proc Natl Acad Sci U S A. 2014 May 27; 111(21): 7647–7652. Published online 2014 May 13. doi: 10.1073/pnas.1321076111

PMCID:: PMC4040570

Abstract Article PDF–1.3M

Select item 401428710.

A Second-generation Protein–Protein Interaction Network of Helicobacter pylori

Roman Häuser, Arnaud Ceol, Seesandra V. Rajagopala, Roberto Mosca, Gabriella Siszler, Nadja Wermke, Patricia Sikorski, Frank Schwarz, Matthias Schick, Stefan Wuchty, Patrick Aloy, Peter Uetz

Mol Cell Proteomics. 2014 May; 13(5): 1318–1329. Published online 2014 Mar 13. doi: 10.1074/mcp.O113.033571

PMCID:: PMC4014287

Abstract Article PDF–2.2M

Select item 366479211.

Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, ε, θ and β reveals a highly flexible arrangement of the proofreading domain

Kiyoshi Ozawa, Nicholas P. Horan, Andrew Robinson, Hiromasa Yagi, Flynn R. Hill, Slobodan Jergic, Zhi-Qiang Xu, Karin V. Loscha, Nan Li, Moeava Tehei, Aaron J. Oakley, Gottfried Otting, Thomas Huber, Nicholas E. Dixon

Nucleic Acids Res. 2013 May; 41(10): 5354–5367. Published online 2013 Apr 10. doi: 10.1093/nar/gkt162

PMCID:: PMC3664792

Abstract Article PDF–6.3M

Select item 364267912.

Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair

Ana Toste Rêgo, Andrew N Holding, Helen Kent, Meindert H Lamers

EMBO J. 2013 May 2; 32(9): 1334–1343. Published online 2013 Apr 2. doi: 10.1038/emboj.2013.68

PMCID:: PMC3642679

Abstract Article PDF–923K

Select item 364267613.

A direct proofreader–clamp interaction stabilizes the Pol III replicase in the polymerization mode

Slobodan Jergic, Nicholas P Horan, Mohamed M Elshenawy, Claire E Mason, Thitima Urathamakul, Kiyoshi Ozawa, Andrew Robinson, Joris M H Goudsmits, Yao Wang, Xuefeng Pan, Jennifer L Beck, Antoine M van Oijen, Thomas Huber, Samir M Hamdan, Nicholas E Dixon

EMBO J. 2013 May 2; 32(9): 1322–1333. Published online 2013 Feb 22. doi: 10.1038/emboj.2012.347