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Select item 67157131.

Probing the solution structure of the E. coli multidrug transporter MdfA using DEER distance measurements with nitroxide and Gd(III) spin labels

Eliane H. Yardeni, Thorsten Bahrenberg, Richard A. Stein, Smriti Mishra, Elia Zomot, Bim Graham, Kellie L. Tuck, Thomas Huber, Eitan Bibi, Hassane S. Mchaourab, Daniella Goldfarb

Sci Rep. 2019; 9: 12528. Published online 2019 Aug 29. doi: 10.1038/s41598-019-48694-0

PMCID:: PMC6715713

Abstract Article PDF–3.3M

Select item 65727622.

Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition

Hsin-Hui Wu, Jindrich Symersky, Min Lu

Commun Biol. 2019; 2: 210. Published online 2019 Jun 17. doi: 10.1038/s42003-019-0446-y

PMCID:: PMC6572762

Abstract Article PDF–1.8M

Select item 61673253.

Outward open conformation of a Major Facilitator Superfamily multidrug/H⁺ antiporter provides insights into switching mechanism

Kumar Nagarathinam, Yoshiko Nakada-Nakura, Christoph Parthier, Tohru Terada, Narinobu Juge, Frank Jaenecke, Kehong Liu, Yunhon Hotta, Takaaki Miyaji, Hiroshi Omote, So Iwata, Norimichi Nomura, Milton T. Stubbs, Mikio Tanabe

Nat Commun. 2018; 9: 4005. Published online 2018 Oct 1. doi: 10.1038/s41467-018-06306-x

PMCID:: PMC6167325

Abstract Article PDF–1.9M

Select item 55052484.

The multidrug-resistance transporter MdfA from Escherichia coli: crystallization and X-ray diffraction analysis

Kumar Nagarathinam, Frank Jaenecke, Yoshiko Nakada-Nakura, Yunhon Hotta, Kehong Liu, So Iwata, Milton T. Stubbs, Norimichi Nomura, Mikio Tanabe

Acta Crystallogr F Struct Biol Commun. 2017 Jul 1; 73(Pt 7): 423–430. Published online 2017 Jun 20. doi: 10.1107/S2053230X17008500

PMCID:: PMC5505248

Abstract Article PDF–1.2M

Select item 45598165.

Substrate-bound structure of the E. coli multidrug resistance transporter MdfA

Jie Heng, Yan Zhao, Ming Liu, Yue Liu, Junping Fan, Xianping Wang, Yongfang Zhao, Xuejun C Zhang

Cell Res. 2015 Sep; 25(9): 1060–1073. Published online 2015 Aug 4. doi: 10.1038/cr.2015.94

PMCID:: PMC4559816

Abstract Article PDF–3.8M

Select item 27816436.

A Promiscuous Conformational Switch in the Secondary Multidrug Transporter MdfA

Nir Fluman, Devora Cohen-Karni, Tali Weiss, Eitan Bibi

J Biol Chem. 2009 Nov 20; 284(47): 32296–32304. Published online 2009 Oct 5. doi: 10.1074/jbc.M109.050658

PMCID:: PMC2781643

Abstract Article PDF–1.4M

Select item 26900027.

A coordinated network of transporters with overlapping specificities provides a robust survival strategy

Nir Tal, Shimon Schuldiner

Proc Natl Acad Sci U S A. 2009 Jun 2; 106(22): 9051–9056. Published online 2009 May 18. doi: 10.1073/pnas.0902400106

PMCID:: PMC2690002

Abstract Article PDF–973K

Select item 26522988.

The Secondary Multidrug/Proton Antiporter MdfA Tolerates Displacements of an Essential Negatively Charged Side Chain

Nadejda Sigal, Nir Fluman, Shira Siemion, Eitan Bibi

J Biol Chem. 2009 Mar 13; 284(11): 6966–6971. doi: 10.1074/jbc.M808877200

PMCID:: PMC2652298

Abstract Article PDF–605K

Select item 18385239.

Antibiotic Stress, Genetic Response and Altered Permeability of E. coli

Miguel Viveiros, Myrielle Dupont, Liliana Rodrigues, Isabel Couto, Anne Davin-Regli, Marta Martins, Jean-Marie Pagès, Leonard Amaral

PLoS One. 2007; 2(4): e365. Published online 2007 Apr 11. doi: 10.1371/journal.pone.0000365

PMCID:: PMC1838523

Abstract Article PDF–290K

Select item 168148110.

Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110

Koji Hayashi, Naoki Morooka, Yoshihiro Yamamoto, Katsutoshi Fujita, Katsumi Isono, Sunju Choi, Eiichi Ohtsubo, Tomoya Baba, Barry L Wanner, Hirotada Mori, Takashi Horiuchi

Mol Syst Biol. 2006; 2: 2006.0007. Published online 2006 Feb 21. doi: 10.1038/msb4100049

PMCID:: PMC1681481

Abstract Article PDF–141K

Select item 154007911.

Growth Phase-Dependent Expression of Drug Exporters in Escherichia coli and Its Contribution to Drug Tolerance

Asuka Kobayashi, Hidetada Hirakawa, Takahiro Hirata, Kunihiko Nishino, Akihito Yamaguchi

J Bacteriol. 2006 Aug; 188(16): 5693–5703. doi: 10.1128/JB.00217-06

PMCID:: PMC1540079

Abstract Article PDF–636K

Select item 154004412.

No Single Irreplaceable Acidic Residues in the Escherichia coli Secondary Multidrug Transporter MdfA

Nadejda Sigal, Shahar Molshanski-Mor, Eitan Bibi

J Bacteriol. 2006 Aug; 188(15): 5635–5639. doi: 10.1128/JB.00422-06

PMCID:: PMC1540044

Abstract Article PDF–293K

Select item 141368113.

Quorum sensing and multidrug transporters in Escherichiacoli

Shirley Yang, Christopher R. Lopez, E. Lynn Zechiedrich

Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7): 2386–2391. Published online 2006 Feb 7. doi: 10.1073/pnas.0502890102

PMCID:: PMC1413681

Abstract Article PDF–551K

Select item 133438514.

TCDB: the Transporter Classification Database for membrane transport protein analyses and information

Milton H. Saier, Jr, Can V. Tran, Ravi D. Barabote

Nucleic Acids Res. 2006 Jan 1; 34(Database issue): D181–D186. Published online 2005 Dec 28. doi: 10.1093/nar/gkj001

PMCID:: PMC1334385

Abstract Article PDF–550K

Select item 132520015.

Escherichia coli K-12: a cooperatively developed annotation snapshot—2005

Monica Riley, Takashi Abe, Martha B. Arnaud, Mary K.B. Berlyn, Frederick R. Blattner, Roy R. Chaudhuri, Jeremy D. Glasner, Takashi Horiuchi, Ingrid M. Keseler, Takehide Kosuge, Hirotada Mori, Nicole T. Perna, Guy Plunkett, III, Kenneth E. Rudd, Margrethe H. Serres, Gavin H. Thomas, Nicholas R. Thomson, David Wishart, Barry L. Wanner

Nucleic Acids Res. 2006; 34(1): 1–9. Published online 2006 Jan 5. doi: 10.1093/nar/gkj405